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ErbB2 / HER2 Protein & Antibody

Human Epidermal Growth Factor Receptor 2

ErbB2 / HER2 Alternative Names

HER2, HER-2, ERBB2, CD340, NEU, NGL, TKR1, c-erbB-2, HER-2/neu [Homo sapiens]

HER2, HER-2, Erbb2, Erbb-2, RP23-355L10.8, Neu, c-erbB2, c-neu, mKIAA3023 [Mus musculus]

ErbB2 / HER2 Protein & Antibody

Sino Biological offers a comprehensive set of research tools (proteins, antibodies) for EGF related research. All of our antibodies were generated with recombinant full length protein as immunogen, which ensures better binding affinity and specificity to the native protein.

ErbB2 / HER2 Protein, Recombinant

Molecule Species Description //For Detailed Info. and Price------CLICK! Cat. No
ErbB2/HER2 Human ErbB2/HER2/Fc Protein, Recombinant 10004-H02H
ErbB2/HER2 Human ErbB2/HER2 Protein, Recombinant 10004-H08H
ErbB2/HER2 Human ErbB2 / HER2 / CD340 (676-1255) Protein, Recombinant, with GST Tag 10004-H20B1
ErbB2/HER2 Mouse ErbB2/HER2 Protein, Recombinant 50714-M08H
ErbB2/HER2 Mouse ErbB2/HER2 Protein, Recombinant 50714-M02H
ErbB2/HER2 Rat ErbB2/HER2/Fc Protein, Recombinant 80079-R02H
ErbB2/HER2 Rat ErbB2/HER2 Protein, Recombinant 80079-R08H
ErbB2/HER2 Rat ErbB2/HER2 Protein, Recombinant 80079-RCCH
ErbB2/HER2 Rhesus ErbB2/HER2/Fc Protein, Recombinant 90020-C02H
ErbB2/HER2 Rhesus ErbB2/HER2 Protein, Recombinant 90020-C08H

ErbB2 / HER2 Antibody

Molecule Application Description //For Detailed Info. and Price------CLICK! Cat. No
Human
ErbB2/HER2
ELISA Mouse Monoclonal Antibody 10004-MM01
Human
ErbB2/HER2
ELISA Mouse Monoclonal Antibody (Biotin conjugated) 10004-MM01B
Human
ErbB2/HER2
WB Mouse Monoclonal Antibody (Biotin conjugated) 10004-MM02B
Human
ErbB2/HER2
WB, ELISA, Flow Cytometry ErbB2/HER2 Antibody, Rabbit MAb 10004-R002
Human
ErbB2/HER2
WB, ELISA, IHC, Flow Cytometry ErbB2/HER2 Antibody, Rabbit MAb 10004-R511
Human
ErbB2/HER2
Flow Cytometry ErbB2/HER2 Antibody, Rabbit MAb 10004-R511F
Human
ErbB2/HER2
WB, ELISA Rabbit Polyclonal Antibody 10004-RP03
Human
ErbB2/HER2
WB, ELISA Rabbit Polyclonal Antibody (Antigen Affinity Purified) 10004-RP04
Human
ErbB2/HER2
FCM ErbB2 / HER2 / CD340 Antibody ( FITC ) 10004-MM03-F
Rhesus
ErbB2/HER2
WB, ELISA HER2 / ErbB2 Antibody (Antigen Affinity Purified) 90020-RP02
Rhesus
ErbB2/HER2
WB, ELISA HER2 / ErbB2 Antibody 90020-MM01

ErbB2 / HER2 ELISA Kit

Molecule Application Description //For Detailed Info. and Price------CLICK! Cat. No
Human ErbB2/HER2 ELISA ErbB2/HER2 ELISA Kit SEK10004

ErbB2 / HER2 cDNA Clone

Molecule Species Description //For Detailed Info. and Price------CLICK! Cat. No
ErbB2/HER2 Human Homo sapiens ErbB2/HER2 transcript variant 1 cDNA Clone(NM_004448.2) HG10004-M
ErbB2/HER2 Mouse Mouse ErbB2/HER2 cDNA Clone / ORF Clone MG50714-G
HER2/ErbB2 Canine Canine ERBB2 Gene cDNA Clone / ORF Clone DG70024-G
ErbB2/HER2 Rat Rat HER2/ErbB2 cDNA Clone / ORF Clone RG80079-M
ErbB2/HER2 Rhesus Rhesus monkey HER2/ErbB2 cDNA Clone / ORF Clone CG90020-M

ErbB2 / HER2 Related Areas

Enzyme>>Protein Kinase>>Receptor Tyrosine Kinase>>ErbB2/HER2

Signal Transduction>>Protein Kinase>>Receptor Tyrosine Kinase>>ErbB2/HER2

Cancer>>Cancer Biomarkers>>ErbB2/HER2

Cancer>>Growth Factor & Receptor>>EGF Family & Receptor>>ErbB2/HER2

Cancer>>Growth Factor & Receptor>>Receptor Tyrosine Kinase>>ErbB2/HER2

Immunology>>Cluster of Differentiation>>Other>>ErbB2/HER2/CD340

ErbB2 / HER2 Related Products

EGF Receptor Family Protein
Molecule Species Protein
HER1 Human HER1 Protein, Recombinant (Met 1 - Ser 645)
HER1 Human HER1/Fc Protein, Recombinant (Met 1 - Ser 645)
HER1 Human HER1 Protein, Recombinant (Met 1 - Lys 642)
HER3 Human HER3/Fc Protein, Recombinant
HER3 Human HER3 Protein, Recombinant
HER4 Human DAN/NBL1/Fc Protein, Recombinant
EGF Ligands Protein
Molecule Species Protein

EGF

Human EGF/Fc Protein, Recombinant
EGF Human EGF Protein, Recombinant
EGF Receptor Family Antibody
Molecule Species Antibody
Human
HER3/ErbB3
WB, ELISA HER3/ErbB3 Antibody, Rabbit PAb
Human
HER3/ErbB3
WB, ELISA HER3/ErbB3 Antibody, Rabbit PAb (Antigen Affinity Purified)
EGF Receptor Family cDNA Clone
Molecule Species cDNA Clone
HER2 Human Homo sapiens HER2 transcript variant 1 cDNA Clone(NM_004448.2)
HER3 Human Homo sapiens HER3 transcript variant 1 cDNA Clone(NM_001982.2)
HER4 Human Homo sapiens HER4 transcript variant JM-a/CVT-2 cDNA Clone(NM_001042599.1)
EGF Ligands cDNA Clone
Molecule Species cDNA Clone

EGF-L6

Hunan Homo sapiens EGF-L6 cDNA Clone(NM_015507.2)
EGFR/ErbB/HER1 Human Homo sapiens EGFR cDNA Clone

Neurexophilin-1

Human Homo sapiens Neurexophilin-1 cDNA Clone(NM_152745.2)

 

ErbB2 / HER2 Background

Human epidermal growth factor receptor 2 (HER2), also known as ErbB2, NEU, and CD340, is a type I membrane glycoprotein, and belongs to the epidermal growth factor (EGF) receptor family. HER2 protein cannot bind growth factors due to the lacking of ligand binding domain of its own and autoinhibited constitutively. However, HER2 forms a heterodimer with other ligand-bound EGF receptor family members, therefore stabilizes ligand binding and enhances kinase-mediated activation of downstream molecules. HER2 plays a key role in development, cell proliferation and differentiation. HER2 gene has been reported to associate with malignancy and a poor prognosis in numerous carcinomas, including breast, prostate, ovarian, lung cancers and so on.

ErbB2 / HER2 Related Studies

  1. Hayes DF, et al. (2007) HER2 and response to paclitaxel in node-positive breast cancer. N Engl J Med. 357(15): 1496-506.
  2. Krawczyk N, et al. (2009) HER2 status on persistent disseminated tumor cells after adjuvant therapy may differ from initial HER2 status on primary tumor. Anticancer Res. 29(10): 4019-24.

 

ErbB2 related areas, pathways, and other information