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KIM-1 / TIM1 / HACVR1 Antibody, Rabbit PAb, Antigen Affinity Purified

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Human KIM1/TIM1 Antibody Product Information
Immunogen:Recombinant Human HAVCR1 protein (Catalog#11051-H07H)
Clone ID:
Ig Type:Rabbit IgG
Concentration:
Endotoxin:
Formulation:0.2 μm filtered solution in PBS with 5% trehalose
Preparation:Produced in rabbits immunized with purified, recombinant Human HAVCR1 / TIM1 / KIM1 (rh HAVCR1 / TIM1 / KIM1; Catalog#11051-H07H; AAC39862.1; Ser 21-Gly 290). HAVCR1 / TIM1 / KIM1 specific IgG was purified by Human HAVCR1 / TIM1 / KIM1 affinity chromatography.
Human KIM1/TIM1 Antibody Usage Guide
Specificity:Human HAVCR1 / TIM1 / KIM1
Application:WB, ELISA, IP

WB: 20-40 μg/mL

ELISA: 0.1-0.2 μg/mL

This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Human KIM1. The detection limit for Human KIM1 is approximately 0.00245 ng/well.

IP: 1-4 μg/mg of lysate

Storage:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Human KIM1/TIM1 Antibody WB Application Image
Human KIM1/TIM1 Antibody IP Application Image
Other KIM1/TIM1 Antibody Products
Reactivity: Human  
Application: ELISA  
    11051-Rn208-100
    11051-Rn208-50
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    Reactivity: Human  
    Application: ELISA  
      11051-RP01-100
      11051-RP01-200
      11051-RP01-400
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      Reactivity: Human  
      Application: ELISA  
        11051-RP02-50
        11051-RP02-100
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        Reactivity: Human  
        Application: ELISA  
          11051-RP03-100
          11051-RP03-200
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          Reactivity: Human  
          Application: ELISA  
            11051-MM04-50
            11051-MM04-100
            11051-MM04-200
            50 µg 
            100 µg 
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            Reactivity: Mouse  
            Application: ELISA  
              50321-R257-50
              50321-R257-100
              50 µg 
              100 µg 
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              Reactivity: Mouse  
              Application: ELISA  
                50321-RP01-400
                50321-RP01-100
                50321-RP01-200
                 
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                Reactivity: Mouse  
                Application: ELISA  
                  50321-RP02-200
                  50321-RP02-50
                  50321-RP02-100
                  200 µg 
                  50 µg 
                  100 µg 
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                  Reactivity: Rat  
                  Application: ELISA  
                    80003-R104-50
                    80003-R104-100
                    50 µg 
                    100 µg 
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                    Reactivity: Rat  
                    Application: ELISA  
                      80003-MM05-50
                      80003-MM05-100
                      50 µg 
                      100 µg 
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                      Reactivity: Rat  
                      Application: ELISA  
                        80003-RP01-100
                        80003-RP01-200
                        80003-RP01-400
                        100 µg 
                        200 µg 
                         
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                        Reactivity: Rat  
                        Application: ELISA  
                          80003-RP02-50
                          80003-RP02-100
                          50 µg 
                          100 µg 
                          Add to Cart
                          Reactivity: Rat  
                          Application: ELISA  
                            80003-R601-50
                            80003-R601-100
                            50 µg 
                            100 µg 
                            Add to Cart
                            Reactivity: Cynomolgus  
                            Application: ELISA  
                              90006-R002-50
                              90006-R002-100
                              50 µg 
                              100 µg 
                              Add to Cart
                              Reactivity: Cynomolgus  
                              Application: ELISA  
                                90006-RP01-100
                                90006-RP01-200
                                90006-RP01-400
                                100 µg 
                                200 µg 
                                 
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                                Reactivity: Cynomolgus  
                                Application: ELISA  
                                  90006-RP02-50
                                  90006-RP02-100
                                  90006-RP02-200
                                  50 µg 
                                  100 µg 
                                  200 µg 
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                                  Reactivity: Canine  
                                  Application: ELISA  
                                    70001-RP01-400
                                    70001-RP01-100
                                    70001-RP01-200
                                     
                                    100 µg 
                                    200 µg 
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                                    Reactivity: Canine  
                                    Application: ELISA  
                                      70001-RP02-200
                                      70001-RP02-50
                                      70001-RP02-100
                                      200 µg 
                                      50 µg 
                                      100 µg 
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                                      Reactivity: Canine  
                                      Application: ELISA  IHC-P  
                                      • Slide 1
                                      70001-R202-50
                                      70001-R202-100
                                      50 µg 
                                      100 µg 
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                                      Reactivity: Rhesus  
                                      Application: ELISA  
                                        90006-MM01-50
                                        90006-MM01-100
                                        90006-MM01-200
                                        50 µg 
                                        100 µg 
                                        200 µg 
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                                        Reactivity: Rhesus  
                                        Application: ELISA  
                                          90006-R242-50
                                          90006-R242-100
                                          50 µg 
                                          100 µg 
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                                          TIM-1/KIM-1/HACVR Background

                                          Human HAV cellular receptor 1 (HAVCR1), also known as Kidney injury molecule 1 (KIM-1) and T cell immunoglobulinmucin 1 (TIM-1), is a type â…  integral membrane glycoprotein. KIM-1 protein is widely expressed with highest levels in kidney and testis. It has been shown to play a major role as a human susceptibility gene for asthma, allergy and autoimmunity. IgA1lambda is a specific ligand of KIM-1 protein and that their association has a synergistic effect in virus-receptor interactions. KIM-1 involves in the pathogenesis of acute kidney injury. It had been confirmed that KIM-1 is a human urinary renal dysfunction biomarker. Moreover, KIM-1 protein is a novel regulatory molecule of flow-induced calcium signaling.

                                          Human TIM-1/KIM-1/HACVR References
                                        • Tami C, et al. (2007) Immunoglobulin A (IgA) is a natural ligand of hepatitis A virus cellular receptor 1 (HAVCR1), and the association of IgA with HAVCR1 enhances virus-receptor interactions. J Virol. 81(7): 3437-46.
                                        • Rees AJ, et al. (2008) Kim-1/Tim-1: from biomarker to therapeutic target? Nephrol Dial Transplant. 23(11): 3394-6.
                                        • Chaturvedi S, et al. (2009) Assay validation for KIM-1: human urinary renal dysfunction biomarker. Int J Biol Sci. 5(2): 128-34.
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                                          Catalog: 11051-RP04-50
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                                          All information of our products is subject to change without notice. Please refer to COA enclosed in shipped package for the newest information.
                                          Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"