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HAGH / GLO2 / Glyoxalase II Antibody Datasheet
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|Detection limit is 0.039 ng/well in ELISA|
HAGH / GLO2 / Glyoxalase II Antibody Product Information
Recombinant Human HAGH / GLO2 / Glyoxalase II protein (Catalog#12146-H08E)
|Antibody Type :||Rabbit Polyclonal Antibody ( Antibody Purification Platform )|
|Ig Type :||
|Formulation :||0.2 μm filtered solution in PBS with 5% trehalose|
Produced in rabbits immunized with purified, recombinant Human HAGH / GLO2 / Glyoxalase II (rh HAGH / GLO2 / Glyoxalase II; Catalog#12146-H08E; Q16775-2; Met 1-Asp 260). Total IgG was purified by Protein A affinity chromatography.
HAGH / GLO2 / Glyoxalase II Antibody Usage Guide
Human HAGH / GLO2 / Glyoxalase II
|Western blot :||This antibody can be used at 1-2 μg/mL with the appropriate secondary reagents to detect Human HAGH in WB.|
|Direct ELISA :||This antibody can be used at 0.5-1 μg/mL with the appropriate secondary reagents to detect Human HAGH. The detection limit for Human HAGH is approximately 0.039 ng/well.|
|Storage :||This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
HAGH / GLO2 / Glyoxalase II Antibody Related Products & Topics
|Molecule||Species||Description //For Detailed Info. and Price------CLICK!||Cat. No|
|HAGH/GLO2||Human||HAGH/GLO2/Glyoxalase II Protein, Recombinant||12146-H08E|
|Molecule||Application||Description //For Detailed Info. and Price------CLICK!||Cat. No|
|Human HAGH/GLO2||WB, ELISA||HAGH / GLO2 / Glyoxalase II Antibody||12146-RP01|
|Human HAGH/GLO2||ELISA, IHC-P||HAGH / GLO2 / Glyoxalase II Antibody (Antigen Affinity Purified)||12146-RP02|
HAGH / GLO2 / Glyoxalase II Antibody Background
Hydroxyacylglutathione hydrolase, also known as Glyoxalase II, HAGH and GLO2, is a mitochondrion matrix and cytoplasm protein which belongs to themetallo-beta-lactamase superfamily and Glyoxalase II family. Glyoxalase II (HAGH / GLO2) is a thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid. The glyoxalase II (HAGH / GLO2) activity in normal human muscle was very low, and the activity was unaltered in muscle of patients with Duchenne and other major forms of muscular dystrophies and spinal muscular atrophy. The selective decrease of glyoxalase I activity in recessively inherited muscular dystrophies may have some relevance to some phases of these disease processes.
- Daniels R.J., et al., 2001, Hum. Mol. Genet. 10: 339-352.
- Ota T., et al.,2004, Nat. Genet. 36: 40-45.
- Cordell P.A., et al., 2004, J. Biol. Chem. 279: 28653-28661.