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> Influenza A H5N2 Hemagglutinin & Antibody (H5N2 HA) Influenza A H5N2 Hemagglutinin & Antibody (H5N2 HA)
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H5N2 Hemagglutinin & Antibody Products
Influenza Antibody - raised against influenza A H5N2 viruses. View antibody cross-reacting, click!
| Product (CLICK for detailed Info. and price) |
Species | Antibody Type |
Application | Cat No |
| Influenza A H5N2 Hemagglutinin (HA) Antibody | Influenza A H5N2 Virus | Rabbit PAb | WB, ELISA | 11699-RP01 |
| Influenza A H5N2 Hemagglutinin (HA) Antibody (Antigen Affinity Purified) | Influenza A H5N2 Virus | Rabbit PAb | WB, ELISA | 11699-RP02 |
Influenza Hemagglutinin (HA) Protein: H5N2, A/American green-winged teal/California/HKWF609/07
| Product (CLICK for detailed Info. and price) | Species | Molecule | Description | Cat No |
| Influenza Hemagglutinin (HA) Protein H5N2, A/American green-winged teal/California/HKWF609/07 |
Influenza A H5N2 Virus | HA | His Tag | 11699-V08H |
| Influenza Hemagglutinin (HA) Protein H5N2, A/American green-winged teal/California/HKWF609/07 |
Influenza A H5N2 Virus | HA1 | His Tag | 11699-V08H1 |
Influenza Hemagglutinin (HA) Protein: H5N2, A/ostrich/South Africa/AI1091/2006
| Product (CLICK for detailed Info. and price) | Species | Molecule | Description | Cat No |
| Influenza Hemagglutinin (HA) Protein H5N2, A/ostrich/South Africa/AI1091/2006 |
Influenza A H5N2 Virus | HA1 | His Tag | 40014-V08H1 |
Influenza A H5N2 Hemagglutinin (HA) cDNA clone
| Product (CLICK for detailed Info. and price) | Species | Molecule | Description | Cat No |
| Influenza Hemagglutinin (HA) cDNA clone H5N2, A/American green-winged teal/California/HKWF609/07 |
Influenza A H5N2 Virus | HA | Codon Optimized | VG11699-C |
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H5N2 Hemagglutinin Background
Influenza (flu) is a respiratory infection in mammals and birds. It is caused by an RNA virus in the family Orthomyxoviridae. The virus is divided into three main types (Influenza A, Influenza B, and Influenza C), which are distinguished by differences in two major internal proteins (hemagglutinin (HA) and neuraminidase (NA)). Influenza virus type A is found in a wide variety of bird and mammal species and can undergo major shifts in immunological properties. Influenza B is largely confined to humans and is an important cause of morbidity. Little is known about Influenza C, which is not an important source of morbidity.
Influenza A is further divided into subtypes based on differences in the membrane proteins hemagglutinin (HA) and neuraminidase (NA), which are the most important targets for the immune system. The notation HhNn is used to refer to the subtype comprising the hth discovered Hemagglutinin (HA) protein and the nth discovered neuraminidase (NA) protein. The influenza viral hemagglutinin (HA) is a single-pass type I integral membrane glycoprotein. It is a homo trimer containing a central α helix coil and three spherical heads with the sialic acid binding sites. The influenza virus neuraminidase (NA) protein is a second major surface antigen of the virion. Neuraminidase cleaves terminal sialic acid from glycoproteins or glycolipids, and promotes influenza virus release from infected cells and facilitates virus spread within the respiratory tract.
H5N2 is a subtype of the species Influenza A virus. Low pathogenic avian influenza H5N2 virus in poultry later gained accentuated virulence in the United States and Mexico. A highly pathogenic strain of H5N2 caused flu outbreaks with significant spread to numerous farms, resulting in great economic losses in 1983 in Pennsylvania, USA in chickens and turkeys, in 1994 in Mexico in chickens and a minor outbreak in 1997 in Italy in chickens. In China, inactivated H5N2 has been used as a vaccine for H5N1. Between 2006 and 2008, outbreaks of H5N2 in poultry took place in South Africa, the Dominican Republic, and Taiwan.
The work of Ogata T and colleagues may suggest the first avian influenza H5N2 infection of poultry to affect humans. performed Wilcoxon matched-pairs signed-ranked test on data collected from 257 farmers at 35 chicken farms in Ibaraki Prefecture. it was determined that the H5N2 antibody titers of the second samples of paired sera were significantly higher than those of the first samples (p<0.001). The H5N2 antibody titers of paired sera of 13 subjects increased fourfold or more.
