Glial Cell Markers

Protein Name	Alternative Names	BioChemical Class / Role	Products (Cat NO)
			Protein	Antibody	Gene cDNA clones
Carbonic Anhydrase II	CA II	Belonging to the family of enzymes that catalyze the rapid conversion of carbonic acid to bicarbonate and protons, a reaction that occurs rather slowly in the absence of a catalyst. Carbonic anhydrase inhibitors have been used in clinical to control diseases, such as gastric and duodenal ulcers, osteoporosis, neurological disorders, or mountain sickness.			HG10478-M
FGFR1	CD331	A receptor tyrosine kinase whose ligands are specific members of the fibroblast growth factor family. Mutations in FGFR1 gene have been associated with Pfeiffer syndrome, Jackson-Weiss syndrome, Antley-Bixler syndrome, osteoglophonic dysplasia, and autosomal dominant Kallmann syndrome 2.	10616-H03H, 10616-H08H		HG10616-M, MG50186-M
FGFR2	CD332	A member of the FGFR family. Mutations are associated with several medical conditions: Apert syndrome, Antley-Bixler syndrome, Pfeiffer syndrome, breast cancer and Crouzon syndrome.	10824-H03H, 10824-H08H		HG10824-M
FGFR3	CD333	A member of the fibroblast growth factor receptor family, of which amino acid sequence is highly conserved between members and throughout evolution. Defects in the FGFR3 gene has been associated with several conditions: achondroplasia, bladder cancer, thanatophoric dwarfism and   seborrheic keratosis.	50071-M03H, 50071-M08H		MG50071-M
FGFR4	CD334	A member of FGFR family, and preferentially binds aFGF/FGF1. FGFR4 is overexpressed in gynecological tumor samples, suggesting a role in breast and ovarian tumorigenesis.	10538-H02H, 10538-H03H, 50194-M03H, 50194-M08H	50194-RP01, 50194-RP02	HG10538-M, MG50194-M
MBP		Myelin basic protein (MBP) is thought to play an important role in the process of myelination of nerves in the central nervous system (CNS).			HG11167-M
MOG		A glycoprotein important in the process of myelinization of nerves in the central nervous system (CNS). It is speculated to serve as a necessary “adhesion molecule” to provide structural integrity to the myelin sheath and is known to develop late on the oligodendrocyte. MOG has a role in demyelinating diseases, such as adrenoleukodystrophy, vanishing white matter disease, and multiple sclerosis (MS).	10364-H08E		HG10364-M
Nogo Receptor	RTN4R, NgR	The receptor for reticulon 4, oligodendrocytemyelin glycoprotein and myelin-associated glycoprotein; mediates axonal growth inhibition and may play a role in regulating axonal regeneration and plasticity in the adult central nervous system.	10466-H03H, 50106-M03H, 50106-M08H		HG10466-M, MG50106-M
OMG	OMGP	Oligodendrocyte-myelin glycoprotein
PDGFRA	CD140a	A tyrosine kinase receptor for members of the platelet-derived growth factor family, probably involved in kidney development.	10556-H02H, 10556-H08H, 10556-HCCH		HG10556-M
S100B	S100 beta	A member of the S-100 protein family, glial-specific and expressed primarily by astrocytes. S100B has been implicated to be involved in several neurological, neoplastic diseases.	10181-H01H		HG10181-M
TNFRSF19	TROY	A member of the TNF-receptor superfamily, highly expressed during embryonic development. It is capable of inducing apoptosis by a caspase-independent mechanism, and plays an essential role in embryonic development.	50148-M03H		MG50148-M