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LGALS8 Protein, Antibody, ELISA Kit, cDNA Clone

LGALS8 Related Areas

LGALS8 Related Pathways

LGALS8 Related Product

    LGALS8 Summary & Protein Information

    LGALS8 Background

    Gene Summary: Galectins, such as LGALS8, are beta-galactoside-binding animal lectins with conserved carbohydrate recognition domains (CRDs). Galectins are involved in various biologic processes, including cell signaling, proliferative control, cell adhesion, and cell migration
    General information above from NCBI
    Cofactor: Divalent metal ions (By similarity).
    Subunit structure: Homodimer.
    Domain: Contains two homologous but distinct carbohydrate-binding domains.
    Subcellular location: Cytoplasm (Probable).
    Tissue specificity: Ubiquitous. Selective expression by prostate carcinomas versus normal prostate and benign prostatic hypertrophy.
    Sequence similarity: Contains 2 galectin domains.
    General information above from UniProt

    LGALS8 Alternative Name

    LGALS8 Related Studies

  • Levy Y, et al. (2003) Sustained induction of ERK, protein kinase B, and p70 S6 kinase regulates cell spreading and formation of F-actin microspikes upon ligation of integrins by galectin-8, a mammalian lectin. J Biol Chem. 278(16):14533-42.
  • Nishi N, et al. (2003) Galectin-8 modulates neutrophil function via interaction with integrin alphaM. Glycobiology. 13(11):755-63.
  • Bidon-Wagner N, et al. (2004) Human galectin-8 isoforms and cancer. Glycoconj J. 19(7-9):557-63.
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