Anti-Galectin-1 Antibody

Cat: 10290-RP02
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All Galectin-1 Reagents
Anti-Galectin-1 Antibody (Rabbit Polyclonal antibody) General Information
Product name
Anti-Galectin-1 Antibody
Validated applications
Species reactivity
Reacts with: Human
Human Galectin-1
Recombinant Human Galectin-1 protein (Catalog#10290-HNAE)
Produced in rabbits immunized with purified, recombinant Human Galectin-1 (rh Galectin-1 ; Catalog#10290-HNAE; NP_002296.1; Met 1-Asp 135). Galectin-1 specific IgG was purified by Human Galectin-1 affinity chromatography.
Polyclonal Rabbit IgG
Protein A & Antigen Affinity
0.2 μm filtered solution in PBS with 5% trehalose
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-Galectin-1 Antibody (Rabbit Polyclonal antibody) Validated Applications
Application Dilution Notes
WB 1:500-1:2000  
ELISA 1:5000-1:10000  

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-Galectin-1 Antibody (Rabbit Polyclonal antibody) Images
Human Galectin-1/LGALS1 Western blot (WB) 13168

Anti-Galectin 1 rabbit polyclonal antibody at 1:500 dilution

Lane A: Hela Whole Cell Lysate

Lane B: A431 Whole Cell Lysate

Lane C: HL60 Whole Cell Lysate

Lane D: K562 Whole Cell Lysate

Lysates/proteins at 30 μg per lane.


Goat Anti-Rabbit IgG H&L (Dylight800) at 1/10000 dilution.

Developed using the Odyssey technique.

Performed under reducing conditions.

Predicted band size:15 kDa

Observed band size:26 kDa

Anti-Galectin-1 Antibody Alternative Names
Anti-GAL1 Antibody;Anti-Galectin-1 Antibody;Anti-GBP Antibody
Galectin-1 Background Information

Galectin-1 (Gal-1, GAL1), is a member of the galectins, a family of animal lectins ranging from Caenorhabditis elegans to humans, which is defined by their affinity for beta-galactosides and by significant sequence similarity in the carbohydrate-binding site. It is a homodimer with a subunit molecular mass of 14.5 kDa, which contains six cysteine residues per subunit. The cysteine residues should be in a free state in order to maintain a molecular structure that is capable of showing lectin activity. This endogenous lectin widely expressed at sites of inflammation and tumour growth, has been postulated as an attractive immunosuppressive agent to restore immune cell tolerance and homeostasis in autoimmune and inflammatory settings. On the other hand, galectin-1 contributes to different steps of tumour progression including cell adhesion, migration and tumour-immune escape, suggesting that blockade of galectin-1 might result in therapeutic benefits in cancer. Several potential glycoprotein ligands for galectin-1 have been identified, including lysosome-associated membrane glycoproteins and fibronectin, laminin, as well as T-cell glycoproteins CD43 and CD45. Evidence points to Gal-1 and its ligands as one of the master regulators of such immune responses as T-cell homeostasis and survival, T-cell immune disorders, inflammation and allergies as well as host-pathogen interactions.

Full Name
lectin, galactoside-binding, soluble, 1
  • Gaudet AD, et al. (2005) Expression and functions of galectin-1 in sensory and motoneurons. Curr Drug Targets. 6(4): 419-25.
  • Kadoya T, et al. (2006) Structural and functional studies of galectin-1: a novel axonal regeneration-promoting activity for oxidized galectin-1. Curr Drug Targets. 6(4): 375-83.
  • Camby I, et al. (2006) Galectin-1: a small protein with major functions. Glycobiology. 16(11): 137R-157R.
  • Salatino M, et al. (2008) Galectin-1 as a potential therapeutic target in autoimmune disorders and cancer. Expert Opin Biol Ther. 8(1): 45-57.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-Galectin-1 Antibody Mouse Monoclonal ELISA 80248-MM06
    Anti-Galectin-1 Antibody Rabbit Monoclonal ELISA 80248-R018
    Anti-Galectin-1 Antibody Rabbit Polyclonal ELISA 80248-RP01
    Anti-Galectin-1 Antibody Rabbit Polyclonal WB,ELISA,IP 80248-T52
    Anti-Galectin-1 Antibody Rabbit Polyclonal ELISA 50100-RP01
    Anti-Galectin-1 Antibody Rabbit Monoclonal WB,IP 10290-R001
    Anti-Galectin-1 Antibody Rabbit Monoclonal ELISA,ELISA(Det) 10290-R008
    Anti-Galectin-1 Antibody Rabbit Monoclonal ELISA(Cap) 10290-R015
    Anti-Galectin-1 Antibody Mouse Monoclonal IHC-P 10290-MM01
    Anti-Galectin-1 Antibody Rabbit Polyclonal ELISA 10290-T16
    Anti-Galectin-1 Antibody Mouse Monoclonal ELISA 10290-MM04
    Anti-Galectin-1 Antibody Mouse Monoclonal WB,IP 10290-MM02
    Anti-Galectin-1 Antibody Rabbit Polyclonal ELISA 10290-RP01
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