Anti-GSTM2 Antibody

Cat: 12042-RP02
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Anti-GSTM2 Antibody (Rabbit Polyclonal antibody) General Information
Product name
Anti-GSTM2 Antibody
Validated applications
WB,ELISA
Species reactivity
Reacts with: Human
Specificity
Human GSTM2
Immunogen
Recombinant Human GSTM2 protein (Catalog#12042-H07E)
Preparation
Produced in rabbits immunized with purified, recombinant Human GSTM2 (rh GSTM2; Catalog#12042-H07E; P28161; Met 1-Lys 218). GSTM2 specific IgG was purified by Human GSTM2 affinity chromatography.
Source
Polyclonal Rabbit IgG
Purification
Protein A & Antigen Affinity
Formulation
0.2 μm filtered solution in PBS with 5% trehalose
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-GSTM2 Antibody (Rabbit Polyclonal antibody) Validated Applications
Application Dilution Notes
WB 1:500-1:1000  
ELISA 1:25000-1:50000  

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-GSTM2 Antibody (Rabbit Polyclonal antibody) Images
Human GSTM2 Western blot (WB) 13459

Anti-GSTM2 rabbit polyclonal antibody at 1:500 dilution

Lane A: 293T Whole Cell Lysate

Lysates/proteins at 30 μg per lane.

Secondary

Goat Anti-Rabbit IgG H&L (Dylight800) at 1/10000 dilution.

Developed using the Odyssey technique.

Performed under reducing conditions.

Predicted band size:26 kDa

Observed band size:26 kDa

Anti-GSTM2 Antibody Alternative Names
Anti-GST4 Antibody;Anti-GSTM Antibody;Anti-GSTM2-2 Antibody;Anti-GTHMUS Antibody
GSTM2 Background Information

Glutathione S-transferase Mu 2, also known as GST class-mu 2, GSTM2-2 and GSTM2, is a cytoplasm protein which belongs to the GST superfamily and Mu family. GSTM2 / GST4 contains one GST C-terminal domain and one GST N-terminal domain. The glutathione S-transferases (GSTs) are a multigene family of enzymes largely involved in the detoxification of chemicals. Eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. Butyrate, an important luminal component produced from fermentation of dietary fibers, is an efficient inducer of GSTs and especially of GSTM2. Butyrate may act chemoprotectively by increasing detoxification capabilities in the colon mucosa.

Full Name
glutathione S-transferase mu 2 (muscle)
References
  • Campbell E, et al.,1990, J Biol Chem 265 (16): 9188-93. 
  • Vorachek WR, et al.,1991, Proc Natl Acad Sci USA. 88 (10): 4443-7.
  • Ebert,M.N. et al., 2003, Carcinogenesis. 24 (10):1637-44.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-GSTM2 Antibody Rabbit Polyclonal ELISA 12042-RP01
    Anti-GSTM2 Antibody Rabbit Monoclonal WB,IP 12042-R006
    Anti-GSTM2 Antibody Rabbit Monoclonal ELISA,IP 12042-R011
    Anti-GSTM2 Antibody Rabbit Monoclonal IHC-P 12042-R005
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