Anti-GOLPH2 Antibody

Cat: 13066-MM15
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Anti-GOLPH2 Antibody (Mouse Monoclonal antibody) General Information
Product name
Anti-GOLPH2 Antibody
Validated applications
ELISA
Species reactivity
Reacts with: Human
Specificity
Human GOLPH2
No cross-reactivity in ELISA with E.coli cell lysate in ELISA
Immunogen
Recombinant Human GOLM1 / GP73 protein (Catalog#13066-H07E)
Preparation
This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human GOLM1 / GP73 (rh GOLM1 / GP73; Catalog#13066-H07E; Q8NBJ4-1; Met 1-Leu 401). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
Source
Monoclonal Clone #11F1A7
Purification
Protein A
Formulation
0.2 μm filtered solution in PBS
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-GOLPH2 Antibody (Mouse Monoclonal antibody) Validated Applications
Application Dilution Notes
ELISA 1:1000-1:2000  

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-GOLPH2 Antibody Alternative Names
Anti-bA379P1.3 Antibody;Anti-C9orf155 Antibody;Anti-GOLPH2 Antibody;Anti-GP73 Antibody;Anti-HEL46 Antibody;Anti-PSEC0257 Antibody
GOLPH2 Background Information

Golgi membrane protein 1, also known as Golgi membrane protein GP73, Golgi phosphoprotein 2 and GOLM1, is a protein which belongs to the GOLM1 / CASC4 family. GOLM1 is widely expressed. It is highly expressed in colon, prostate, trachea and stomach. It is expressed at lower level in testis, muscle, lymphoid tissues, white blood cells and spleen. It is predominantly expressed by cells of the epithelial lineage. GOLM1 is expressed at low level in normal liver. Expression significantly increases in virus (HBV, HCV) infected liver. Expression of GOLM1 does not increase in liver disease due to non-viral causes (alcohol-induced liver disease, autoimmune hepatitis). Increased expression in hepatocytes appears to be a general feature of advanced liver disease. In liver tissue from patients with adult giant-cell hepatitis (GCH), GOLM1 is strongly expressed in hepatocyte-derived syncitial giant cells. GOLM1 is constitutively expressed by biliary epithelial cells but not by hepatocytes.

Full Name
golgi membrane protein 1
References
  • Kladney R.D., et al.,(2000), GP73, a novel Golgi-localized protein upregulated by viral infection. Gene 249:53-65.
  • Clark H.F., et al., (2003), The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.Genome Res. 13:2265-2270.
  • Puri S., et al.,(2002), Cycling of early Golgi proteins via the cell surface and endosomes upon lumenal pH disruption.Traffic 3:641-653.
  • Product Description Host Clonality Application Catalog# (PDF)
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    Anti-GOLPH2 Antibody Rabbit Polyclonal ELISA,IHC-P 13066-T24
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    Anti-GOLPH2 Antibody Rabbit Monoclonal ELISA,IHC-P 13066-R037
    Anti-GOLPH2 Antibody Mouse Monoclonal ELISA 13066-MM06
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