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GOLM1 / GP73 Antibody, Mouse MAb

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Human GOLM1/GP73 Antibody Product Information
Immunogen:Recombinant Human GOLM1 / GP73 protein (Catalog#13066-H08H)
Clone ID:9C2D3
Ig Type:Mouse IgG1
Concentration:
Endotoxin:
Formulation:0.2 μm filtered solution in PBS with 5% trehalose
Preparation:This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human GOLM1 / GP73 (rh GOLM1 / GP73; Catalog#13066-H08H; Q8NBJ4-1; Val 40-Leu 401). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
Human GOLM1/GP73 Antibody IHC Application Image
GOLM1 / GP73 Antibody, Mouse MAb, Immunohistochemistry
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Caption:
Immunochemical staining of human GOLM1 in human endometrium with mouse monoclonal antibody (15 µg/mL, formalin-fixed paraffin embedded sections). Positive staining was localized to cytoplasm of uterine gland.
GOLM1 / GP73 Antibody, Mouse MAb, Immunohistochemistry
[Click to enlarge image]
Caption:
Immunochemical staining of human GOLM1 in human liver with mouse monoclonal antibody (15 µg/mL, formalin-fixed paraffin embedded sections). Positive staining was localized to cytoplasm of hepatocyte and interlobular bile duct.
Other GOLM1/GP73 Antibody Products
GOLM1/GP73 Background

Golgi membrane protein 1, also known as Golgi membrane protein GP73, Golgi phosphoprotein 2 and GOLM1, is a protein which belongs to the GOLM1 / CASC4 family. GOLM1 is widely expressed. It is highly expressed in colon, prostate, trachea and stomach. It is expressed at lower level in testis, muscle, lymphoid tissues, white blood cells and spleen. It is predominantly expressed by cells of the epithelial lineage. GOLM1 is expressed at low level in normal liver. Expression significantly increases in virus (HBV, HCV) infected liver. Expression of GOLM1 does not increase in liver disease due to non-viral causes (alcohol-induced liver disease, autoimmune hepatitis). Increased expression in hepatocytes appears to be a general feature of advanced liver disease. In liver tissue from patients with adult giant-cell hepatitis (GCH), GOLM1 is strongly expressed in hepatocyte-derived syncitial giant cells. GOLM1 is constitutively expressed by biliary epithelial cells but not by hepatocytes.

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