- EGFR Signaling Pathway
- TGF-beta Signaling
- Canonical Wnt Signaling
- non-Canonical Wnt Signaling
- Notch Signaling
- p53 Pathway
- NF-kB Pathway
- Cytokine Signaling
|Catalog||Size (Price)||Quantity||In Stock||Operation|
Glia maturation factor, beta Protein Datasheet
GMFB Protein Price Inquiry ( Available Sizes )
GMFB Protein Product Information
A DNA sequence encoding the human GMFB (Met1-His142) was expressed.
GMFB Protein QC Testing
|Purity:||> 95 % as determined by SDS-PAGE||SDS-PAGE:
|Endotoxin:||Please contact us for more information.|
|Stability:||Samples are stable for up to twelve months from date of receipt at -70℃|
|Predicted N terminal:||Met|
The recombinant human GMFB consists of 142 amino acids and predicts a molecular mass of 16.7 KDa. It migrates as an approximately 17 KDa band in SDS-PAGE under reducing conditions.
|Formulation:||Lyophilized from sterile PBS, PH 7.4.
GMFB Protein Usage Guide
|Storage:||Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.|
|Reconstitution:||A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.|
GMFB Protein Related Products & Topics
GMFB Protein Description
GMFB is a member of the actin-binding proteins ADF family, GMF subfamily. It is a nerve growth factor and contains 1 ADF-H domain. GMFB causes differentiation of brain cells, stimulation of neural regeneration, and inhibition of proliferation of tumor cells. It is phosphorylated after phorbol ester stimulation, and is crucial for the nervous system. GMFB overexpression in astrocytes results in the increase of BDNF production. GMFB expression is increased by exercise, thus BDNF is important for exercise-induction of BDNF.
- Kim W. et al., 2011, Mol Cell. 44 (2): 325-40.
- Zaheer S. et al., 2011, Neuroscience. 194: 227-33.
- Danielsen JM. et al., 2011, Mol Cell Proteomics. 10 (3): M110.003590.