Text Size:AAA

GITR / TNFRSF18

GITR / TNFRSF18 Protein & Antibody

TNFRSF18 Related Information

GITR / TNFRSF18N


This gene encodes a member of the TNF-receptor superfamily. GITR has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this GITR gene encoding distinct isoforms have been reported. [provided by RefSeq, Feb 2011]

OMIM-Description for GITR / TNFRSF18N


Members of the tumor necrosis factor (TNF; 191160) and TNF receptor (TNFR) superfamilies, such as GITR, regulate diverse biologic functions, including cell proliferation, differentiation, and survival. For further background information on the TNF and TNFR superfamilies, see TNFRSF1A (191190).

GITR / TNFRSF18


Tumor necrosis factor receptor superfamily member 18 (TNFRSF18) also known as activation-inducible TNFR family receptor (AITR) or glucocorticoid-induced TNFR-related protein (GITR) is a protein that in humans is encoded by the TNFRSF18 gene.

GITR / TNFRSF18 Alternative Names

activation-inducible TNFR family receptor,AITR,CD357,GITR,GITR-D,glucocorticoid-induced TNFR-related protein,RP5-902P8.2,TNF receptor superfamily activation-inducible protein,tumor necrosis factor receptor superfamily member 18, [human]
AITR,Gitr,glucocorticoid-induced TNFR-related protein,RP23-118E21.6,tumor necrosis factor receptor superfamily member 18, [mouse]

GITR / TNFRSF18 Related Products

GITR / TNFRSF18 Proteins

Product nameProduct name
Rat GITR / TNFRSF18 Protein (Fc Tag)Human GITR / TNFRSF18 Protein (Fc Tag)

GITR / TNFRSF18 Antibodies

Product nameProduct name

GITR / TNFRSF18 cDNA Clones

Product nameProduct name
Human TNFRSF18 Gene cDNA Clone (full-length ORF Clone), expression ready, N-Myc-taggedRat TNFRSF18 Gene cDNA Clone (full-length ORF Clone), expression ready, C-HA-taggedRat TNFRSF18 Gene cDNA Clone (full-length ORF Clone), expression ready, untaggedRat TNFRSF18 Gene cDNA Clone (full-length ORF Clone), expression ready, C-His-taggedHuman TNFRSF18 Gene cDNA Clone (full-length ORF Clone), expression ready, N-His-taggedRat TNFRSF18 Gene cDNA Clone (full-length ORF Clone), expression ready, N-FLAG-taggedHuman TNFRSF18 Gene cDNA Clone (full-length ORF Clone), expression ready, untaggedHuman TNFRSF18 Gene cDNA Clone (full-length ORF Clone), expression ready, C-Myc-taggedRat TNFRSF18 Gene cDNA Clone (full-length ORF Clone), expression ready, C-Myc-taggedRat TNFRSF18 Gene cDNA Clone (full-length ORF Clone), expression ready, C-FLAG-taggedHuman TNFRSF18 Gene cDNA Clone (full-length ORF Clone), expression ready, C-HA-taggedHuman TNFRSF18 Gene cDNA Clone (full-length ORF Clone), expression ready, N-HA-taggedHuman TNFRSF18 Gene cDNA Clone (full-length ORF Clone), expression ready, C-His-taggedHuman TNFRSF18 Gene cDNA Clone (full-length ORF Clone), expression ready, N-FLAG-taggedRat TNFRSF18 Gene cDNA Clone (full-length ORF Clone)Human TNFRSF18 Gene cDNA Clone (full-length ORF Clone), expression ready, C-FLAG-taggedHuman TNFRSF18 Gene cDNA Clone (full-length ORF Clone), expression ready, untaggedHuman TNFRSF18 Gene cDNA Clone (full-length ORF Clone)Rat TNFRSF18 Gene cDNA Clone (full-length ORF Clone), expression ready, N-Myc-taggedRat TNFRSF18 Gene cDNA Clone (full-length ORF Clone), expression ready, N-His-taggedRat TNFRSF18 Gene cDNA Clone (full-length ORF Clone), expression ready, N-HA-tagged

GITR / TNFRSF18 ELISA

Product nameProduct name
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"