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GITR/TNFRSF18/CD357

GITR/TNFRSF18/CD357 Protein & Antibody

TNFRSF18 Related Information

Entrez Gene Summary for GITR/TNFRSF18/CD357


This gene encodes a member of the TNF-receptor superfamily. GITR has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this GITR gene encoding distinct isoforms have been reported. [provided by RefSeq, Feb 2011]

OMIM-Description for GITR/TNFRSF18/CD357


Members of the tumor necrosis factor (TNF; 191160) and TNF receptor (TNFR) superfamilies, such as GITR, regulate diverse biologic functions, including cell proliferation, differentiation, and survival. For further background information on the TNF and TNFR superfamilies, see TNFRSF1A (191190).

.zh=GITR/TNFRSF18/CD357


Tumor necrosis factor receptor superfamily member 18 (TNFRSF18) also known as activation-inducible TNFR family receptor (AITR) or glucocorticoid-induced TNFR-related protein (GITR) is a protein that in humans is encoded by the TNFRSF18 gene.

GITR/TNFRSF18/CD357 Alternative Names

activation-inducible TNFR family receptor,AITR,CD357,GITR,GITR-D,glucocorticoid-induced TNFR-related protein,RP5-902P8.2,TNF receptor superfamily activation-inducible protein,tumor necrosis factor receptor superfamily member 18, [human]
AITR,Gitr,glucocorticoid-induced TNFR-related protein,RP23-118E21.6,tumor necrosis factor receptor superfamily member 18, [mouse]

GITR/TNFRSF18/CD357 Related Products

GITR/TNFRSF18/CD357 Proteins

Product nameProduct name
Human GITR / TNFRSF18 Protein (His Tag, ECD)Rat GITR / TNFRSF18 Protein (Fc Tag)Human GITR / TNFRSF18 Protein (Fc Tag)

GITR/TNFRSF18/CD357 Antibodies

Product nameProduct name
GITR / TNFRSF18 Antibody, Rabbit PAb, Antigen Affinity PurifiedGITR/TNFRSF18/CD357 Antibody, Mouse MAb

GITR/TNFRSF18/CD357 cDNA Clones

Product nameProduct name
Human GITR/TNFRSF18/CD357 Gene ORF cDNA clone expression plasmid, N-Myc tagRat GITR/TNFRSF18/CD357 Gene ORF cDNA clone expression plasmid, C-HA tagRat GITR/TNFRSF18/CD357 Gene ORF cDNA clone expression plasmidRat GITR/TNFRSF18/CD357 Gene ORF cDNA clone expression plasmid, C-His tagHuman GITR/TNFRSF18/CD357 Gene ORF cDNA clone expression plasmid, C-GFPSpark tagHuman GITR/TNFRSF18/CD357 Gene ORF cDNA clone expression plasmid, N-His tagRat GITR/TNFRSF18/CD357 Gene ORF cDNA clone expression plasmid, N-Flag tagCynomolgus GITR/TNFRSF18/CD357 Gene ORF cDNA clone in cloning vectorHuman GITR/TNFRSF18/CD357 Gene ORF cDNA clone expression plasmid, C-Myc tagRat GITR/TNFRSF18/CD357 Gene ORF cDNA clone expression plasmid, C-Myc tagRat GITR/TNFRSF18/CD357 Gene ORF cDNA clone expression plasmid, C-GFPSpark tagRat GITR/TNFRSF18/CD357 Gene ORF cDNA clone expression plasmid, C-Flag tagRat GITR/TNFRSF18/CD357 Gene ORF cDNA clone expression plasmid, C-OFPSpark tagHuman GITR/TNFRSF18/CD357 Gene ORF cDNA clone expression plasmid, C-HA tagHuman GITR/TNFRSF18/CD357 Gene ORF cDNA clone expression plasmid, N-HA tagHuman GITR/TNFRSF18/CD357 Gene ORF cDNA clone expression plasmid, C-His tagHuman GITR/TNFRSF18/CD357 Gene ORF cDNA clone expression plasmid, N-Flag tagRat GITR/TNFRSF18/CD357 Gene ORF cDNA clone in cloning vectorHuman GITR/TNFRSF18/CD357 Gene ORF cDNA clone expression plasmid, C-Flag tagHuman GITR/TNFRSF18/CD357 Gene ORF cDNA clone expression plasmidHuman GITR/TNFRSF18/CD357 Gene ORF cDNA clone in cloning vectorRat GITR/TNFRSF18/CD357 Gene ORF cDNA clone expression plasmid, N-Myc tagRat GITR/TNFRSF18/CD357 Gene ORF cDNA clone expression plasmid, N-His tagMouse GITR/TNFRSF18/CD357 transcript variant 1 Gene ORF cDNA clone in cloning vectorRat GITR/TNFRSF18/CD357 Gene ORF cDNA clone expression plasmid, N-HA tagHuman GITR/TNFRSF18/CD357 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag

GITR/TNFRSF18/CD357 ELISA

Product nameProduct name
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"