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Rat GITR / TNFRSF18 Protein (Fc Tag)
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Rat GITR / TNFRSF18 Protein (Fc Tag) (Cytokine) PDF Download

Catalog   Size (Price) Quantity In Stock Operation
80192-R02H  
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Tumor necrosis factor receptor superfamily, member 18 Protein Datasheet

 

GITR / TNFRSF18 Protein Price Inquiry ( Available Sizes )

GITR / TNFRSF18 Protein Product Information

Synonym : TNFRSF18
Protein Construction:

A DNA sequence encoding the rat TNFRSF18 (Q5M835) (Met1-Lys121) was expressed, fused with the Fc region of human IgG1 at the C-terminus.

Source: Rat
Expression Host: Human Cells

GITR / TNFRSF18 Protein QC Testing

Purity: > 95% as determined by SDS-PAGE SDS-PAGE:
SDS-PAGE

GITR / TNFRSF18 protein

Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method
Stability: Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N terminal: Glu 25
Molecular Mass:

The recombinant rat TNFRSF18/Fc is a disulfide-linked homodimer. The reduced monomer comprises 338 amino acids and has a predicted molecular mass of 37.7 kDa. The apparent molecular mass of the protein is approximately 47 kDa in SDS-PAGE under reducing conditions.

Formulation: Lyophilized from sterile PBS, pH7.4.
  1. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
  2. Please contact us for any concerns or special requirements.

GITR / TNFRSF18 Protein Usage Guide

Storage: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

GITR / TNFRSF18 Protein Related Products & Topics

Related Areas:

Proteins:

Antibodies:

GITR / TNFRSF18 Protein Description

GITR, also known as TNFRSF18(CD357), belongs to the tumor necrosis factor receptor (TNF-R) superfamily. It is the receptor for TNFSF18. GITR and its ligand are important costimulatory molecules in the pathogenesis of autoimmune diseases. It also mediates NF-kappa-B activation via the TRAF2/NIK pathway. GITR plays a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. GITR may be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death.

References

  1. Won B. et al., 1999, J Biol Chem. 274 (10): 6056-61.
  2. Nocentini G. et al., 1997, Proc Natl Acad Sci. 94 (12): 6216-21.
  3. Kim YS. et al., 2007, Oncol Rep. 18 (5): 1189-94.
 

 

GITR (TNFRSF18) related areas, pathways, and other information

All TNF Proteins

Product nameProduct name
4-1BB / CD137 / TNFRSF9 ProteinNGFR/ P75 Protein (His Tag)
4-1BB / CD137 / TNFRSF9 Protein (His Tag)Mouse PGLYRP / TNFSF3L Protein (His Tag)
Mouse 4-1BB / TNFRSF9 / CD137 ProteinRELT / TNFRSF19L Protein
Canine 4-1BB / TNFRSF9 Protein (His Tag)RELT / TNFRSF19L Protein (His Tag)
Mouse 4-1BBL / TNFSF9 ProteinTNFa Protein (Native)
Rat TNFSF9 Protein Mouse TNFa Protein (Native)
Rat TNFSF9 Protein (His Tag)Canine TNFa / TNFSF1A Protein (Native)
BAFF / TNFSF13B ProteinCynomolgus TNFa / TNFSF1A Protein (Native)
BAFF / TNFSF13B ProteinRat TNFa / TNF-alpha Protein (Native)
BAFF / TNFSF13B Protein (Native)Ferret TNFa / TNF-alpha Protein (Native)
Cynomolgus BAFF / TNFSF13B ProteinTNFRSF1A / TNFRI / CD120a Protein
Mouse BAFFR / TNFRSF13C / CD268 ProteinTNFRSF1A / TNFRI / CD120a Protein (His Tag)
Rat BAFFR / TNFRSF13C Protein (His Tag)Mouse TNFRSF1A / TNFRI / CD120a Protein (His Tag)
Rat BAFFR / TNFRSF13C ProteinMouse TNFRI / TNFRSF1A / CD120a Protein
CD27 / TNFRSF7 ProteinRat TNFRSF1A / TNFR1 Protein
Mouse CD27 / TNFRSF7 ProteinRat TNFRSF1A / TNFR1 Protein (His Tag)
Mouse CD27 / TNFRSF7 Protein (His Tag)TNFRSF1B / TNFR2 / CD120b Protein
CD27 / TNFRSF7 ProteinTNFRSF1B / TNFR2 / CD120b Protein (His Tag)
Cynomolgus CD27 / TNFRSF7 ProteinMouse TNFRSF1B / TNFR2 / CD120b Protein
CD27 / TNFRSF7 Protein (His Tag)Mouse TNFRSF1B / TNFR2 / CD120b Protein (His Tag)
CD30 Ligand / TNFSF8 ProteinCynomolgus TNFRSF1B Protein (His Tag)
Rat CD30 Ligand / TNFSF8 ProteinCynomolgus TNFRSF1B Protein
Cynomolgus CD30 Ligand / TNFSF8 ProteinTNFRSF1B (aa 1-268, 196 Met / Arg) Protein (His Tag)
Cynomolgus CD30 Ligand / TNFSF8 Protein (His Tag)Rat TNFRSF11A Protein (His Tag)
Rat CD30 Ligand / TNFSF8 ProteinRat TNFRSF11A Protein
CD40 / TNFRSF5 ProteinTNFRSF11B / OCIF Protein (His Tag)
CD40 / TNFRSF5 Protein (His Tag)Cynomolgus TNFRSF11B Protein
Mouse CD40 / TNFRSF5 ProteinFn14 / TNFRSF12A Protein
Rat TNFRSF5 / CD40 ProteinTNFRSF13B / TACI / CD267 Protein (His Tag)
Rat TNFRSF5 / CD40 Protein (His Tag)TNFRSF14 / HVEA / HVEM Protein
Cynomolgus TNFRSF5 / CD40 ProteinMouse HVEM / TNFRSF14 Protein
Cynomolgus TNFRSF5 / CD40 Protein (His Tag)TNFRSF14 / HVEA / HVEM Protein (His Tag)
Canine TNFRSF5 / CD40 ProteinCynomolgus TNFRSF14 / HVEA / HVEM Protein
Canine TNFRSF5 / CD40 ProteinMouse TNFRSF14 / HVEA / HVEM Protein
Canine TNFRSF5 / CD40 Protein (His Tag)Mouse TNFRSF17 Protein
CD40L / CD154 / TNFSF5 Protein (His Tag)Mouse BCMA / TNFRSF17 Protein
CD40L / CD154 / TNFSF5 ProteinTNFRSF17 / BCMA / CD269 Protein
Mouse CD40L / CD154 / TNFSF5 ProteinRat TNFRSF17 Protein
Rat CD40LG / CD40L / TNFSF5 ProteinCynomolgus TNFRSF17 Protein
Cynomolgus CD40LG / CD40L / TNFSF5 Protein Rat GITR / TNFRSF18 Protein
Canine CD40LG / CD40L / TNFSF5 ProteinGITR / TNFRSF18 Protein
Canine CD40LG / CD40L / TNFSF5 ProteinMouse TNFRSF19 / TROY Protein
CD70 / CD27L / TNFSF7 ProteinMouse TNFRSF19 / TROY Protein (His Tag)
Rat CD70 ProteinTNFRSF19 / TROY Protein
Rat CD70 Protein (His Tag)TNFRSF19 / TROY Protein (His Tag)
FAS / TNFRSF6 / CD95 ProteinTNFRSF25 / DDR3 / APO3 Protein (Fc Tag)
Mouse FAS / TNFRSF6 / CD95 Protein (His Tag)TNFRSF4 / CD134 Protein
CD95 / Fas / TNFRSF6 Protein (His Tag)TNFRSF4 / CD134 Protein (His Tag)
Rat FAS / TNFRSF6 / CD95 Protein (His Tag)Mouse OX40 / CD134 / TNFRSF4 Protein
Rat FAS / TNFRSF6 / CD95 ProteinCD30 / TNFRSF8 Protein
Cynomolgus FAS / TNFRSF6 / CD95 ProteinTNFRSF8 / CD30 Protein (His Tag)
Cynomolgus FAS / TNFRSF6 / CD95 ProteinTNFSF10 / APO2L / TRAIL / CD253 Protein (His Tag)
Fas Ligand / FASLG / CD95L Protein (His Tag)TNFSF10 / APO2L / TRAIL / CD253 Protein (Native)
DcR3 / TNFRSF6B Protein (His Tag)Mouse TNFSF10 (aa 118-291) Protein (His Tag)
DCR3 / TNFRSF6B ProteinCynomolgus TNFSF10 Protein (Native)
DR6 / TNFRSF21 ProteinTNFSF11 / RANKL / CD254 Protein
DR6 / TNFRSF21 ProteinMouse TNFSF11 / OPGL / CD254 Protein
DR6 / TNFRSF21 Protein (His Tag)TNFSF11 / OPGL / CD254 Protein
Mouse DR6 / TNFRSF21 Protein (His Tag)TNFSF11 / OPGL / CD254 Protein
EDA2R / XEDAR / TNFRSF27 Protein (His Tag)RANKL / OPGL / TNFSF11 / CD254 Protein
Rat EDA2R / TNFRSF27 ProteinCynomolgus RANKL / OPGL / TNFSF11 Protein
Rat EDA2R / TNFRSF27 Protein (His Tag)Rat TNFSF12 Protein
Mouse EDA2R / TNFRSF27 ProteinCynomolgus / Human TNFSF12 Protein
Cynomolgus XEDAR / EDA2R / TNFRSF27 ProteinMouse TNFSF13 Protein
EDAR / DL ProteinRat TNFSF15 / TL1A Protein
EDAR / DL Protein (His Tag)Cynomolgus OX-40L / TNFSF4 Protein
Rat EDAR ProteinTNFRSF10A / CD261 / APO2 Protein
Cynomolgus EDAR ProteinTNFRSF10A / CD261 / APO2 Protein
Cynomolgus EDAR Protein (His Tag)TNFRSF10A / CD261 / APO2 Protein (His Tag)
TNFSF14 ProteinTNFRSF10B / TRAILR2 / CD262 Protein
LTA / TNFB / TNF-beta Protein (Native)TNFRSF10B / TRAILR2 / CD262 Protein (His Tag)
Rat LTBR Protein (His Tag)Mouse TRAILR2 / TNFRSF10B Protein (His Tag)
Cynomolgus LTBR ProteinMouse TRAILR2 / TNFRSF10B Protein
Rat LTBR ProteinTRAILR4 / TNFRSF10D / DCR2 / CD264 Protein
Mouse NGFR / P75 Protein (His Tag)TRAILR4 / TNFRSF10D / DCR2 Protein (His Tag)
Mouse NGFR / P75 ProteinCynomolgus TNFRSF10D Protein
NGFR / P75 ProteinCynomolgus TNFRSF10D Protein (His Tag)

All TNF Antibodies

Product nameProduct name
CD137 / 4-1BB Antibody *TNFa Antibody
4-1BBL / TNFSF9 AntibodyTNFa / TNFalpha / TNFSF2 Antibody
4-1BBL / TNFSF9 Antibody *TNFa / TNFalpha / TNFSF2 Antibody *
4-1BBL / TNFSF9 AntibodyTNF-alpha Antibody
4-1BBL / CD137L / TNFSF9 Antibody ( FITC )TNF-alpha Antibody
4-1BBL / CD137L / TNFSF9 Antibody ( PE )TNF-alpha Antibody *
BAFF / TNFSF13B AntibodyTNF-alpha Antibody
BAFF / TNFSF13B Antibody *TNF-alpha Antibody *
CD27 / TNFRSF7 AntibodyTNFA / TNF-alpha Antibody
CD27 / TNFRSF7 Antibody *TNFA / TNF-alpha Antibody
CD27 / TNFRSF7 Antibody ( FITC )TNF-alpha / TNFa Antibody
CD27 / TNFRSF7 Antibody ( FITC )TNF-alpha Antibody ( FITC )
CD27 AntibodyTNF-alpha Antibody ( FITC )
CD27 AntibodyTNF-alpha / TNFa / TNFSF2 Antibody *
CD27 / TNFRSF7 Antibody ( PE )TNFRI / TNFRSF1A / CD120a Antibody
CD27 / TNFRSF7 Antibody ( FITC )TNFR1 / CD120a / TNFRSF1A Antibody *
CD27 AntibodyTNFR1 / CD120a / TNFRSF1A Antibody
CD27 AntibodyTNFRSF1B / TNFR2 / CD120b Antibody
CD27 / TNFRSF7 Antibody ( FITC )TNFRSF1B / TNFR2 / CD120b Antibody *
CD27 / TNFRSF7 Antibody ( PE )TNFRSF1B / TNFR2 / CD120b Antibody
CD40 / TNFRSF5 / Bp50 AntibodyTNFRSF1B / TNFRII / TNFR2 Antibody
CD40 / TNFRSF5 / Bp50 Antibody *TNFR2 / CD120b / TNFRSF1B Antibody
CD40 / TNFRSF5 / Bp50 AntibodyTNFR2 / CD120b / TNFRSF1B Antibody *
CD40 / TNFRSF5 / Bp50 AntibodyTNFR2 / CD120b / TNFRSF1B Antibody
CD40 / TNFRSF5 Antibody ( FITC )Osteoprotegerin / TNFRSF11B Antibody
CD40L / CD154 / TNFSF5 AntibodyTNFRSF19 / TROY Antibody
CD40L / CD154 / TNFSF5 AntibodyTNFRSF19 / TROY Antibody *
FAS / CD95 AntibodyTNFRSF19 / TROY Antibody
FAS / CD95 Antibody * TNFRSF4 / CD134 Antibody
CD95 / Fas / TNFRSF6 AntibodyTNFRSF4 / CD134 Antibody *
CD95 / Fas / TNFRSF6 Antibody * TNFRSF4 / CD134 Antibody
CD95 / APO-1 / TNFRSF6 / FAS AntibodyTNFRSF4 / CD134 Antibody
CD95 / APO-1 / TNFRSF6 / FAS Antibody ( FITC )CD30 / TNFRSF8 Antibody
CD95 / APO-1 / TNFRSF6 / FAS AntibodyCD30 / TNFRSF8 Antibody *
CD95 / APO-1 / TNFRSF6 / FAS Antibody ( PE )CD30 / TNFRSF8 Antibody
CD95 / APO-1 / TNFRSF6 / FAS AntibodyCD30 / TNFRSF8 Antibody
FAS / TNFRSF6 / CD95 AntibodyCD30 / TNFRSF8 Antibody
FAS / TNFRSF6 / CD95 AntibodyCD30 / TNFRSF8 Antibody ( FITC )
CD95 / APO-1 / TNFRSF6 / FAS Antibody ( FITC )CD30 / TNFRSF8 Antibody ( PE )
CD95 / APO-1 / TNFRSF6 / FAS Antibody ( PE )TNFSF10 / TRAIL / APO-2L Antibody *
DR6 / TNFRSF21 AntibodyTRAIL R1 / CD261 / TNFRSF10A Antibody *
DR6 / TNFRSF21 Antibody * TRAIL R1 / CD261 / TNFRSF10A Antibody
DR6 / TNFRSF21 AntibodyTNFRSF10B / TRAILR2 / CD262 Antibody
XEDAR / EDA2R AntibodyTNFRSF10B / TRAILR2 / CD262 Antibody *
XEDAR / EDA2R Antibody *TNFRSF10B / TRAILR2 / CD262 Antibody
XEDAR / EDA2R AntibodyTRAILR2 / TNFRSF10B Antibody
TNF-beta / TNFSF1 alpha Antibody *TRAILR2 / TNFRSF10B Antibody *
TNF-beta / TNFSF1 alpha AntibodyTRAIL R2 / TNFRSF10B / CD262 Antibody
RELT / TNFRSF19L AntibodyTRAIL R2 / TNFRSF10B / CD262 Antibody ( PE )
RELT / TNFRSF19L Antibody *TRAIL R4 / CD264 / TNFRSF10D Antibody
RELT / TNFRSF19L AntibodyTRAIL R4 / CD264 / TNFRSF10D Antibody
TNFa AntibodyTRAIL R4 / CD264 / TNFRSF10D Antibody *
TNFa AntibodyTRAIL R4 / CD264 / TNFRSF10D Antibody
TNFa Antibody* Antigen Affinity Purified
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"