All GGT1 reagents are produced in house and quality controlled, including 4 GGT1 Antibody, 24 GGT1 Gene, 1 GGT1 Lysate, 1 GGT1 Protein, 2 GGT1 qPCR. All GGT1 reagents are ready to use.
Recombinant GGT1 proteins are expressed by HEK293 Cells with fusion tags as N-His.
GGT1antibodies are validated with different applications, which are WB, ELISA, IHC-P.
GGT1cDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each GGT1 of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.
GGT1 belongs to the gamma-glutamyltransferase protein family. Many members of this family have not yet been fully characterized and some of which may represent pseudogenes. GGT1 is composed of a heavy chain and a light chain. It catalyzes the transfer of the glutamyl moiety of glutathione to a variety of amino acids and dipeptide acceptors. GGT1 also initiates extracellular glutathione (GSH) breakdown, provides cells with a local cysteine supply and contributes to maintain intracelular GSH level. As part of the cell antioxidant defense mechanism, GGT1 can be detected in fetal and adult kidney and liver, adult pancreas, stomach, intestine, placenta and lung. Defects in GGT1 can cause glutathionuria which is known as an autosomal recessive disease.