Anti-GGT1 Antibody

Cat: 80364-RP01
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Anti-GGT1 Antibody (Rabbit Polyclonal antibody) General Information
Product name
Anti-GGT1 Antibody
Validated applications
ELISA
Species reactivity
Reacts with: Rat
Specificity
Rat GGT1
Immunogen
Recombinant Rat GGT1 protein (Catalog#80364-R07H)
Preparation
Produced in rabbits immunized with purified, recombinant Rat GGT1 (rR GGT1; Catalog#80364-R07H; P07314; Pro27-Tyr568). Total IgG was purified by Protein A affinity chromatography.
Source
Polyclonal Rabbit IgG
Purification
Protein A
Formulation
0.2 μm filtered solution in PBS with 5% trehalose
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-GGT1 Antibody (Rabbit Polyclonal antibody) Validated Applications
Application Dilution Notes
ELISA 1:1000-1:2000  

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

GGT1 Background Information

GGT1 belongs to the gamma-glutamyltransferase protein family. Many members of this family have not yet been fully characterized and some of which may represent pseudogenes. GGT1 is composed of a heavy chain and a light chain. It catalyzes the transfer of the glutamyl moiety of glutathione to a variety of amino acids and dipeptide acceptors. GGT1 also initiates extracellular glutathione (GSH) breakdown, provides cells with a local cysteine supply and contributes to maintain intracelular GSH level. As part of the cell antioxidant defense mechanism, GGT1 can be detected in fetal and adult kidney and liver, adult pancreas, stomach, intestine, placenta and lung. Defects in GGT1 can cause glutathionuria which is known as an autosomal recessive disease.

Full Name
gamma-glutamyltransferase 1
References
  • Bulle F, et al. (1987) Assignment of the human gamma-glutamyl transferase gene to the long arm of chromosome 22. Hum Genet. 76(3):283-6.
  • Tate SS, et al. (1988) Renal gamma-glutamyl transpeptidases: structural and immunological studies. Arch Biochem Biophys. 262(2):397-408.
  • Tate SS, et al. (1988) In vitro translation and processing of human hepatoma cell (Hep G2) gamma-glutamyl transpeptidase. Biochem Biophys Res Commun. 154(3):1167-73.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-GGT1 Antibody Rabbit Polyclonal ELISA,IHC-P 80364-T24
    Anti-GGT1 Antibody Rabbit Polyclonal IHC-P 101924-T08
    Anti-GGT1 Antibody Rabbit Polyclonal WB 100416-T32
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