Anti-GGCT Antibody (Rabbit Polyclonal antibody) General Information
Reacts with: Human
Recombinant Human GGCT protein (Catalog#14366-H07E)
Produced in rabbits immunized with purified, recombinant Human GGCT (rh GGCT; Catalog#14366-H07E; O75223-1; Met1-Leu188). Total IgG was purified by Protein A affinity chromatography.
Polyclonal Rabbit IgG
0.2 μm filtered solution in PBS with 5% trehalose
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-GGCT Antibody (Rabbit Polyclonal antibody) Validated Applications
**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********
Anti-GGCT Antibody Alternative Names
Anti-C7orf24 Antibody;Anti-CRF21 Antibody;Anti-GCTG Antibody;Anti-GGC Antibody
GGCT Background Information
GGCT belongs to the gamma-glutamylcyclotransferase family. It catalyzes the formation of 5-oxoproline from gamma-glutamyl dipeptides, the penultimate step in glutathione catabolism. GGCT may play a significant role in glutathione homeostasis. GGCT also induces release of cytochrome c from mitochondria with resultant induction of apoptosis. Pseudogenes of GGCT gene are located on the long arm of chromosome 5 and the short arm of chromosomes 2 and 20. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Wagner SA. et al., 2011, Mol Cell Proteomics. 10 (10): M111.013284. Kim W. et al., 2011, Mol Cell. 44 (2): 325-40. Amano T. et al., 2012, J Histochem Cytochem. 60 (1): 76-86.