GFAP cDNA ORF Clone in Cloning Vector, Human

Cat: HG12167-G
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GFAP cDNA ORF Clone in Cloning Vector, Human General Information
Gene
Species
Human
NCBI Ref Seq
RefSeq ORF Size
1299 bp
Sequence Description
Identical with the Gene Bank Ref. ID sequence.
Description
Full length Clone DNA of Human glial fibrillary acidic protein.
Plasmid
Vector
pGEM-T Vector
Sequencing Primers
SP6 and T7 or M13-47 and RV-M
Quality Control
The plasmid is confirmed by full-length sequencing.
Screening
Antibiotic in E.coli
Ampicillin
Storage & Shipping
Shipping
Each tube contains lyophilized plasmid.
Storage
The lyophilized plasmid can be stored at ambient temperature for three months.
GFAP cDNA ORF Neucleotide Sequence and Amino Acid Sequence Information

**Sino Biological guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories.**

GFAP cDNA ORF Clone in Cloning Vector, Human Alternative Names
ALXDRD cDNA ORF Clone, Human
GFAP Background Information

GFAP is a cell-specific marker which belongs to the intermediate filament family. It can distinguish astrocytes from other glial cells during development. GFAP is expressed in cells lacking fibronectin. It is a type III intermediate filaments protein which contains three domains: the head, rod and tail domains. GFAP functions in many important entral nervous system (CNS) processes, including cell communication and the functioning of the blood brain barrier. Improper GFAP regulation can cause multiple disorders. Defects in GFAP is related to Alexander disease which is a rare disorder of the central nervous system. It is a progressive leukoencephalopathy whose hallmark is the widespread accumulation of Rosenthal fibers which are cytoplasmic inclusions in astrocytes.

Full Name
glial fibrillary acidic protein
References
  • Buniatian G, et al., 1998, Biology of the cell. 90(1): 53-61.
  • Chen YS, et al., 2011, Experimental Cell Research. 317(16): 2252-66.
  • Isaacs A, et al., 1998, Genomics. 51(1): 152-4.
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    GFAP cDNA ORF Clone, Human, Related Products

    Product Name Catalog#(PDF)
    GFAP cDNA ORF Clone, Human, untagged HG12167-UT
    GFAP cDNA ORF Clone, Human, C-GFPSpark® tag HG12167-ACG
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    GFAP cDNA ORF Clone, Human, N-GFPSpark® tag HG12167-ANG
    GFAP cDNA ORF Clone, Human, C-OFPSpark® tag HG12167-ACR
    GFAP cDNA ORF Clone, Human, N-OFPSpark® tag HG12167-ANR
    GFAP cDNA ORF Clone, Human, C-DDK (Flag®) tag HG12167-CF
    GFAP cDNA ORF Clone, Human, N-DDK (Flag®) tag HG12167-NF
    GFAP cDNA ORF Clone, Human, C-His tag HG12167-CH
    GFAP cDNA ORF Clone, Human, N-His tag HG12167-NH
    GFAP cDNA ORF Clone, Human, C-HA tag HG12167-CY
    GFAP cDNA ORF Clone, Human, N-HA tag HG12167-NY
    GFAP cDNA ORF Clone, Human, C-Myc tag HG12167-CM
    GFAP cDNA ORF Clone, Human, N-Myc tag HG12167-NM
    GFAP qPCR Primer Pairs, Human HP101799
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