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Human GBP-2 / GBP2 Protein (His Tag)
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Human GBP-2 / GBP2 Protein (His Tag) PDF Download

Catalog   Size (Price) Quantity In Stock Operation
13930-H08H  
YES   
 

Protein Production & Purification Service | Recombinant Cytokines & Growth Factors

Guanylate binding protein 2, interferon-inducible Protein Datasheet

 

GBP-2 / GBP2 Protein Price Inquiry ( Available Sizes )

GBP-2 / GBP2 Protein Product Information

Synonym : GBP2
Protein Construction:

A DNA sequence encoding the human GBP2 (AAH73163.1) (Met1-Cys588) was expressed with a polyhistidine tag at the C-terminus.

Source: Human
Expression Host: Human Cells

GBP-2 / GBP2 Protein QC Testing

Purity: > 90% as determined by SDS-PAGE SDS-PAGE:
SDS-PAGE

GBP-2 / GBP2 protein

Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method
Stability: Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N terminal: Met
Molecular Mass:

The recombinant human GBP2 consists of  599 amino acids and predicts a molecular mass of 68.3 KDa. It migrates as an approximately 62 KDa band in SDS-PAGE under reducing conditions.

Formulation: Lyophilized from sterile PBS, pH 7.4.
  1. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
  2. Please contact us for any concerns or special requirements.

GBP-2 / GBP2 Protein Usage Guide

Storage: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

GBP-2 / GBP2 Protein Related Products & Topics

Related Areas:

Proteins:

Antibodies:

GBP-2 / GBP2 Protein Description

GBP-2 is a member of the guanylate-binding protein (GBP) family. As GTPases induced by IFN-gamma (Interferon-inducible GTPase), GBPS are key to the protective immunity against microbial and viral pathogens. GBPS are characterized by their ability to specifically bind guanine nucleotides (GMP, GDP, and GTP). GBP-2 is a GTPase that converts GTP to GDP and GMP. It binds GTP, GDP and GMP. GBP-2 hydrolyzes GTP very efficiently. GDP rather than GMP is the major reaction product. GBP-2 is induced by interferons that have antiviral effects and inhibit tumor cell proliferation.

References

  1. Strausberg RL. et al., 2003, Proc Natl Acad Sci. 99 (26): 16899-903.
  2. Wistow G. et al., 2002, Mol Vis. 8: 205-20.
  3. Neun R et al., 1996, FEBS Lett. 390 (1): 69-72.
 

 

GBP-2 related areas, pathways, and other information

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"