All GCSF Receptor reagents are produced in house and quality controlled, including 5 GCSF Receptor Antibody, 1 GCSF Receptor ELISA, 12 GCSF Receptor Gene, 3 GCSF Receptor Lysate, 3 GCSF Receptor Protein, 1 GCSF Receptor qPCR. All GCSF Receptor reagents are ready to use.
Recombinant GCSF Receptor proteins are expressed by HEK293 Cells with fusion tags as C-human IgG1-Fc, C-His, C-cleavage.
GCSF Receptorantibodies are validated with different applications, which are ELISA, ELISA(Det), ELISA(Cap), ICC/IF, IF, FCM.
GCSF ReceptorcDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each GCSF Receptor of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.
GCSF ReceptorELISA Kit are quality controlled by 8 internation QC standard which guarantee every ELISA Kit with high quality.
Granulocyte Colony Stimulating Factor Receptor (G-CSFR), also known as CD114, which belongs to the cytokine receptor superfamily, is a cell surface receptor for colony stimulating factor 3 (CSF3). It is a critical regulator of granulopoiesis. This type I membrane protein has a composite structure consisting of an immunoglobulin(Ig)-like domain, a cytokine receptor-homologous (CRH) domain and three fibronectin type III (FNIII) domains in the extracellular region. Mutations in the G-CSF receptor leading to carboxy-terminal truncation transduce hyperproliferative growth responses, and are implicated in the pathological progression of severe congenital neutropenia (SCN) to acute myelogenous leukemia (AML). Additionally, autocrine/paracrine stimulation of G-CSFR may be important in the biology of solid tumors, including metastasis.