Anti-G-CSF Antibody

Cat: 10007-R104
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All G-CSF Reagents
Anti-G-CSF Antibody (Rabbit Monoclonal antibody) General Information
Product name
Anti-G-CSF Antibody
Validated applications
Species reactivity
Reacts with: Human
Human G-CSF
Recombinant Human G-CSF Protein (Catalog#10007-HNCE)
This antibody was obtained from a rabbit immunized with purified, recombinant Human G-CSF (rh G-CSF; Catalog#10007-HNCE; Ala 30-Pro 204; NP_757373.1) .
Monoclonal Rabbit IgG Clone #104
Protein A
0.2 μm filtered solution in PBS
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-G-CSF Antibody (Rabbit Monoclonal antibody) Validated Applications
Application Dilution Notes
ELISA 1:5000-1:10000  

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-G-CSF Antibody Alternative Names
Anti-C17orf33 Antibody;Anti-C17orf33OS Antibody;Anti-CSF3OS Antibody;Anti-G-CSF Antibody;Anti-GCSF Antibody
G-CSF Background Information

Granulocyte-colony stimulating factor (G-CSF) is a growth factor and an essential cytokine belonging to the CSF family of hormone-like glycoproteins. It is produced by numerous cell types including immune and endothelial cells. G-CSF binding to its receptor G-CSF-R which belongs to the cytokine receptor type I family depends on the interaction of alpha-helical motifs of the former and two fibronectin type III as well as an immunoglobulin-like domain of the latter. Recent animal studies have also revealed that G-CSF activates multiple signaling pathways, such as Akt and also the Janus family kinase-2 and signal transducer and activation of transcription-3 (Jak2-STAT3) pathway, thereby promoting survival, proliferation, differentiation and mobilisation of haematopoietic stem and progenitor cells. G-CSF is a cytokine that have been demonstrated to improve cardiac function and perfusion in myocardial infarction. And it was initially evaluated as a stem cell mobilizer and erythropoietin as a cytoprotective agent. G-CSF prevents left ventricular remodeling after myocardial infarction by decreasing cardiomyocyte death and by increasing the number of blood vessels, suggesting the importance of direct actions of G-CSF on the myocardium rather than through mobilization and differentiation of stem cells. Accordingly, recombinant human (rh)G-CSF has been extensively used in clinical haematology and oncology to enable bone marrow transplantation or to treat chemotherapy-associated neutropenia. In preclinical study, G-CSF improved cardiac function and perfusion by angiomyogenesis and protection of cardiomyocytes in myocardial infarction.

Immune Checkpoint   Immunotherapy   Cancer Immunotherapy   Targeted Therapy

Full Name
colony stimulating factor 3 (granulocyte)
  • Takano H, et al. (2007) G-CSF therapy for acute myocardial infarction. Trends Pharmacol Sci. 28(10): 512-7.
  • Klocke R, et al. (2008) Granulocyte colony-stimulating factor (G-CSF) for cardio- and cerebrovascular regenerative applications. Curr Med Chem. 15(10): 968-77.
  • Kang HJ, et al. (2008) G-CSF- and erythropoietin-based cell therapy: a promising strategy for angiomyogenesis in myocardial infarction. Expert Rev Cardiovasc Ther. 6(5): 703-13.
  • Beekman R, et al. (2010) G-CSF and its receptor in myeloid malignancy. Blood. 115(25): 5131-6.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-G-CSF Antibody Rabbit Polyclonal ELISA 10007-T16
    Anti-G-CSF Antibody Rabbit Polyclonal ELISA 10007-RP01
    Anti-G-CSF Antibody Rabbit Polyclonal ELISA 10007-RP02
    Anti-G-CSF Antibody Rabbit Monoclonal ELISA,ELISA(Det) 10007-R243
    Anti-G-CSF Antibody Mouse Monoclonal ELISA 10007-MM07
    Anti-G-CSF Antibody Mouse Monoclonal ELISA 10007-MM32
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