All Frizzled 2 reagents are produced in house and quality controlled, including 14 Frizzled 2 Gene, 1 Frizzled 2 Lysate, 1 Frizzled 2 Protein, 1 Frizzled 2 qPCR. All Frizzled 2 reagents are ready to use.
Recombinant Frizzled 2 proteins are expressed by HEK293 Cells with fusion tags as N-human IgG1-Fc.
Frizzled 2 cDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each Frizzled 2 of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.
FZD2 may be a tumor suppressor gene in salivary adenoid cystic carcinomas (SACCs) that inhibits cell growth and migration. OMOD2 is a rare skeletal dysplasia and characterized by facial dysmorphism and shortness of the upper extremities and first metacarpal bones, and heterozygous FZD2 mutations may be disease-causing for OMOD2. heterozygous de novo mutation (G434V) in the frizzled class receptor 2 (FZD2) gene in a patient with distinct facial features including hypertelorism, bilateral cleft lip/palate, short nose with a broad nasal bridge, microretrognathia, and bilateral shortness of the upper limbs,