All Fractalkine reagents are produced in house and quality controlled, including 7 Fractalkine Antibody, 2 Fractalkine ELISA, 52 Fractalkine Gene, 6 Fractalkine Lysate, 8 Fractalkine Protein, 3 Fractalkine qPCR. All Fractalkine reagents are ready to use.
Recombinant Fractalkine proteins are expressed by Yeast, HEK293 Cells with fusion tags as C-His, C-human IgG1-Fc, C-cleavage.
Fractalkineantibodies are validated with different applications, which are FCM, ELISA(Det), ELISA, ELISA(Cap), IHC-P.
FractalkinecDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each Fractalkine of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.
FractalkineELISA Kit are quality controlled by 8 internation QC standard which guarantee every ELISA Kit with high quality.
Fractalkine or Chemokine (C-X3-C motif) ligand 1 (CX3CL1) is a member of the CX3C chemokine family. Fractalkine / CX3CL1 is a unique chemokine that functions not only as a chemoattractant but also as an adhesion molecule and is expressed on endothelial cells activated by proinflammatory cytokines, such as interferon-gamma and tumor necrosis factor-alpha. Fractalkine/CX3CL1 is expressed in a membrane-bound form on activated endothelial cells and mediates attachment and firm adhesion of T cells, monocytes and NK cells. Fractalkine / CX3CL1 is associated with dendritic cells (DC) in epidermis and lymphoid organs. The fractalkine receptor, CX3CR1, is expressed on cytotoxic effector lymphocytes, including natural killer (NK) cells and cytotoxic T lymphocytes, which contain high levels of intracellular perforin and granzyme B, and on macrophages. Soluble fractalkine causes migration of NK cells, cytotoxic T lymphocytes, and macrophages, whereas the membrane-bound form captures and enhances the subsequent migration of these cells in response to secondary stimulation with other chemokines.