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> Flow Cytometry (FACS) Antibody to CD4 Flow Cytometry (FACS) Antibody to CD4
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Flow Cytometry (FACS) Antibody to CD4 Products
All CD4 Products list
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Flow Cytometry (FACS) Antibody to CD4
Flow Cytometry (FACS) Antibody to CD4 ( FITC ) 10400-R005-F
Browse Flow Cytometry (FACS) Antibody to CD4 Products by Following Categories
CD4 Protein , Antibody, ELISA Kit, cDNA Clone
Flow Cytometry (FACS) Antibody to CD4
– Flow Cytometry (FACS) Antibody to Human CD4
– Flow Cytometry (FACS) Antibody to Mouse CD4
– Flow Cytometry (FACS) Antibody to Rat CD4
– Flow Cytometry (FACS) Antibody to Rhesus CD4
– Flow Cytometry (FACS) Antibody to Cynomolgus CD4
– Flow Cytometry (FACS) Antibody to Canine (Dog) CD4
– Flow Cytometry (FACS) Antibody to Ferret CD4
– Flow Cytometry (FACS) Antibody to Bovine CD4
Antibody to CD4
Flow Cytometry (FACS) Antibody to CD4 Related Products
ELISA Antibody to CD4
– ELISA Antibody to Human CD4
– ELISA Antibody to Mouse CD4
– ELISA Antibody to Rat CD4
– ELISA Antibody to Rhesus CD4
– ELISA Antibody to Cynomolgus CD4
– ELISA Antibody to Canine (Dog) CD4
– ELISA Antibody to Ferret CD4
– ELISA Antibody to Bovine CD4
Western Blot Antibody to CD4
– Western Blot Antibody to Human CD4
– Western Blot Antibody to Mouse CD4
– Western Blot Antibody to Rat CD4
– Western Blot Antibody to Rhesus CD4
– Western Blot Antibody to Cynomolgus CD4
– Western Blot Antibody to Canine (Dog) CD4
– Western Blot Antibody to Ferret CD4
– Western Blot Antibody to Bovine CD4
Immunohistochemistry (IHC) Antibody to CD4
– Immunohistochemistry (IHC) Antibody to Human CD4
– Immunohistochemistry (IHC) Antibody to Mouse CD4
– Immunohistochemistry (IHC) Antibody to Rat CD4
– Immunohistochemistry (IHC) Antibody to Rhesus CD4
– Immunohistochemistry (IHC) Antibody to Cynomolgus CD4
– Immunohistochemistry (IHC) Antibody to Canine (Dog) CD4
– Immunohistochemistry (IHC) Antibody to Ferret CD4
– Immunohistochemistry (IHC) Antibody to Bovine CD4
Browse CD4 Antibody by Following Categories
CD4 Antibody
– Human CD4 Antibody
– Mouse CD4 Antibody
– Rat CD4 Antibody
– Rhesus CD4 Antibody
– Cynomolgus CD4 Antibody
– Canine (Dog) CD4 Antibody
– Ferret CD4 Antibody
– Bovine CD4 Antibody
Additional CD4 Products
Summary for CD4
T-cell surface glycoprotein CD4, is a single-pass type I membrane protein. CD4 contains three Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. CD4 is a glycoprotein expressed on the surface of T helper cells, regulatory T cells, monocytes, macrophages, and dendritic cells. The CD4 surface determinant, previously associated as a phenotypic marker for helper/inducer subsets of T lymphocytes, has now been critically identified as the binding/entry protein for human immunodeficiency viruses (HIV). The human CD4 molecule is readily detectable on monocytes, T lymphocytes, and brain tissues. All human tissue sources of CD4 bind radiolabeled gp120 to the same relative degree; however, the murine homologous protein, L3T4, does not bind the HIV envelope protein. CD4 is a co-receptor that assists the T cell receptor (TCR) to activate its T cell following an interaction with an antigen presenting cell. Using its portion that resides inside the T cell, CD4 amplifies the signal generated by the TCR. CD4 interacts directly with MHC class II molecules on the surface of the antigen presenting cell via its extracellular domain. The CD4 molecule is currently the object of intense interest and investigation both because of its role in normal T-cell function, and because of its role in HIV infection. CD4 is a primary receptor used by HIV-1 to gain entry into host T cells. HIV infection leads to a progressive reduction of the number of T cells possessing CD4 receptors.
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