Fibronectin (Protein|Antibody|cDNA Clone|ELISA Kit)

All Fibronectin reagents are produced in house and quality controlled, including 6 Fibronectin Antibody, 2 Fibronectin IPKit, 1 Fibronectin Lysate, 1 Fibronectin Protein. All Fibronectin reagents are ready to use.

Recombinant Fibronectin proteins are expressed by HEK293 Cells with fusion tags as C-His.

Fibronectinantibodies are validated with different applications, which are WB, ELISA, IP, ICC/IF, IF.

Fibronectin Protein (1)

Species

Fibronectin Protein, Human, Recombinant (His Tag)

10314-H08H

Expression host: HEK293 Cells

Human Fibronectin Protein 8654
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Fibronectin Antibody (6)

Application Clonality
Host

Anti-Fibronectin Antibody

10314-R014

Application: WB,ELISA,IP

Clonality: MAb

Human Fibronectin Western blot (WB) 6946

Anti-Fibronectin Antibody

10314-T50

Application: WB,ELISA,ICC/IF,IF

Clonality: PAb

Anti-Fibronectin Antibody

10314-MM02

Application: ELISA

Clonality: MAb

Anti-Fibronectin Antibody

10314-RP01

Application: WB,ELISA

Clonality: PAb

Human Fibronectin Western blot (WB) 13180

Anti-Fibronectin Antibody

10314-T16

Application: ELISA

Clonality: PAb

Anti-Fibronectin Antibody

10314-RP03

Application: WB,ELISA,IP

Clonality: PAb

Human Fibronectin Immunoprecipitation(IP) 7972
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Fibronectin IP Kit (2)

Fibronectin Lysate (1)

Fibronectin (FN) is a glycoprotein component of the extracellular matrix of the extracellular matrix (ECM) with roles in embryogenesis, development, and wound healing. More recently, FN has emerged as player in platelet thrombus formation and diseases associated with thrombosis including vascular remodeling, atherosclerosis, and cardiac repair following a myocardial infarct. Each monomer of FN consists of three types of homologous repeating units, that is 12 type I repeats, two type II repeats and 15-17 type III repeats. The occurrence of multiple isoforms results from alternative mRNA splicing of the ED-A, ED-B and III-CS regions, and subsequent post-translational modification. As an ECM component and one of the primary cell adhesion molecules, Fibronectin can be a ligand for fibrin, heparin, chondroitin sulfate, collagen/gelatin, as well as many integrin receptors through which FN mediates the variety of cellular signaling pathways. The study of solid human tumors showed among the early signs of malignant transformation the fragmentation of pericellular FN, concommitent with the increase of its production by the peritumoral stroma. These results should encourage further investigations concerning the potential importance of Fn production and breakdown during cancer progression. FN1 expression has been described to increase significantly from the morula towards the early blastocyst stage, suggesting that FN1 may also be involved in early blastocyst formation. The fragment 2 of FN comprises the first 7 FN type III repeats and is suggested to be important for self association during fibril growth via the key module III2.

Protein
Antibody
IPKit
Lysate
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