Fibroblast Growth Factor & Receptor

Fibroblast Growth Factor & Receptor Products

Sino biological offers a comprehensive set of tools for research on fibroblast growth factor family and their receptors.

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FGF Ligands

aFGF / FGF1	FGF9	FGF14^*
bFGF / FGF2	FGF10	FGF16^*
FGF5^*	FGF11^*	FGF18
FGF6	FGF12^*	FGF19
FGF7 / KGF^*	FGF13^*	FGF21

FGF Receptors

FGFR1 / CD331	FGFR3 / CD333	FGFRL1 / FGFR5
FGFR2 / CD332	FGFR4 / CD334

Fibroblast Growth Factor & Receptor Background

Fibroblast growth factors are a family of proteins involved in angiogenesis, cell growth, wound healing, embryonic development and many other aspects of development. Fibroblast growth factors play key roles in the processes of proliferation and differentiation of wide variety of cells and tissues. In humans, 22 members of the FGF family have been identified, all of which are structurally related signaling molecules. The activity of FGF family ligands is mediated by the FGF receptor tyrosine kinases, including FGFR1, FGFR2, FGFR3 and FGFR4.

FGF receptor binding

Fibroblast Growth Factor & Receptor Related Studies

Blaber, M, et al. (1996) X-ray crystal structure of human acidic fibroblast growth factor. Biochemistry 35: 2086-94.
Ornitz, DM, et al. (2001) Fibroblast growth factors. Genome Biol 2: 1-12.
Kamo K, et al. (2009) Effects of single and cyclical local injections of basic fibroblast growth factor on cancellous bone defects in rabbits. J Orthop Sci. 14(6):811-9.
Kliewer SA, et al. (2010) Fibroblast growth factor 21: from pharmacology to physiology. Am J Clin Nutr. 91(1):254S-257S.