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Fc Receptor / Fc Receptors

Fc Receptor Products (Recombinant Proteins & Antibodies & Genes & ELISA Kits)

  • Fc Receptor Product list :

Fc Receptor Proteins back to product list

Product Name Species Tag Cat &
Human FCAR / CD89 Protein Human His 10414-H08H
Rat FCAR / CD89 Protein Rat His 80014-R08H
Human CD64 / FCGR1A Protein Human His 10256-H08H
Human CD64 / FCGR1A Protein Human AVI 10256-H27H
Human CD64 / FCGR1A Protein  Human AVI 10256-H27H-B
Mouse CD64 / FCGR1 Protein Mouse His 50086-M08H
Mouse CD64 / FCGR1 Protein Mouse AVI 50086-M27H
Mouse FCGR1 / CD64 Protein Mouse AVI 50086-M27H-B
Rat CD64 / FCGR1A Protein Rat His 80016-R08H
Human CD32a / FCGR2A Protein (167 Arg) Human His 10374-H08H
Human CD32a / FCGR2A Protein (166 Arg) Human His 10374-H08B
Human CD32a / FCGR2A Protein (167 Arg) Human human IgG1-Fc 10374-H02H
Human CD32a / FCGR2A Protein (167 His) Human His 10374-H08H1
Human CD32a / FCGR2A Protein (167 His) Human AVI 10374-H27H1
Human CD32a / FCGR2A Protein (167 Arg) Human AVI 10374-H27H
Human CD32a / FCGR2A Protein (167 His) Human AVI 10374-H27H1-B
Human CD32a / FCGR2A Protein (167 Arg) Human AVI 10374-H27H-B
Human CD32a / FCGR2A Protein (167 Arg) Human His 10374-H08C
Human CD32a / FCGR2A  Protein(167 His) Human His 10374-H08C1
Cynomolgus CD32a / FCGR2A Protein Cynomolgus His 90015-C08H
Cynomolgus CD32a / FCGR2A Protein Cynomolgus AVI 90015-C27H
Cynomolgus CD32a / FCGR2A Protein Cynomolgus AVI 90015-C27H-B
Cynomolgus CD32a / FCGR2A Protein Cynomolgus His 90016-C08H
Human CD32b / FCGR2B Protein Human His 10259-H08H
Human CD32b / FCGR2B Protein Human AVI 10259-H27H
Human CD32b / FCGR2B Protein Human AVI 10259-H27H-B
Human CD32b / FCGR2B Protein  Human His 10259-H08C
Mouse CD32 / FCGR2B Protein Mouse His 50030-M08H
Mouse CD32 / FCGR2B Protein Mouse AVI 50030-M27H
Mouse CD32 / FCGR2B Protein Mouse AVI 50030-M27H-B
Rat CD32b / FCGR2B Protein Rat His 80018-R08H
Cynomolgus CD32b / FCGR2B Protein Cynomolgus His 90014-C08H
Cynomolgus CD32b / FCGR2B Protein Cynomolgus AVI 90014-C27H
Cynomolgus CD32b / FCGR2B Protein Cynomolgus AVI 90014-C27H-B
Human CD16a / FCGR3A Protein (176 Phe) Human His 10389-H08H
Human CD16a / FCGR3A Protein (176 Val) Human His 10389-H08H1
Human CD16a / FCGR3A Protein (176 Phe) Human AVI 10389-H27H
Human CD16a / FCGR3A Protein (176 Val) Human AVI 10389-H27H1
Human CD16a / FCGR3A Protein (176 Val) Human AVI 10389-H27H1-B
Human CD16a / FCGR3A Protein (176 Phe) Human AVI 10389-H27H-B
Human CD16a / FCGR3A Protein (176 Val) Human His 10389-H08C1
Human CD16a / FCGR3A Protein  Human His 10389-H08C
Rat CD16a / FCGR3A Protein Rat His 80017-R08H
Human CD16b / FCGR3B Protein Human His 11046-H08H
Human CD16b / FCGR3B Protein  Human Native 11046-HNAE
Human CD16b / FCGR3B Protein  Human His 11046-H08C
Mouse CD16-2 / FCGR4 Protein Mouse AVI 50036-M08H
Mouse CD16-2 / FCGR4 Protein Mouse AVI 50036-M27H
Mouse FCGR4 / CD16-2 Protein Mouse AVI 50036-M27H-B
Mouse FCGR3 / CD16 Protein Mouse His 50326-M08H
Cynomolgus CD16 / FCGR3 Protein Cynomolgus AVI 90013-C27H
Cynomolgus CD16 / FCGR3 Protein Cynomolgus His 90013-C08H
Cynomolgus CD16 / FCGR3 Protein Cynomolgus AVI 90013-C27H-B
Human CD23 / FCER2 Protein Human His 10261-H07H
Mouse FCER2A / CD23 Protein Mouse His 50695-M07H
Rat CD23 / FCER2 / FCER2A Protein Rat human IgG1-Fc 80208-R01H
Human FCER1A / FcERI Protein Human His 13193-H08H
Mouse FCERI / FCER1A Protein Mouse human IgG1-Fc 50935-M02H
Human FCRL1 / IFGP1 Protein  Human His 11536-H08H
Mouse FCRL1 / IFGP1 Protein Mouse His 50947-M08H
Human FCGRT/B2M Heterodimer Protein Human His CT009-H08H

 

Fc Receptor Antibodies back to product list

Product Name React Application Cat &
CD89 / FACR Antibody,Rabbit Pab Human WB, ELISA 10414-RP01
CD89 / FACR Antibody,Rabbit Pab (Antigen Affinity Purified) Human WB, ELISA 10414-RP02
CD89 / FACR Antibody,Rabbit Mab Human WB, ELISA 10414-R006
CD89 / FACR Antibody,Mouse Pab Human ELISA 10414-MM02
CD89 / FACR Antibody (FITC),Mouse Mab Human FCM 10414-MM02-F
CD89 / FCAR Antibody, Rabbit Pab Rat WB, ELISA 80014-RP01
CD89 / FCAR Antibody, Rabbit Pab (Antigen Affinity Purified) Rat WB, ELISA 80014-RP02
CD64 / FCGR1A Antibody, Mouse Mab Human ELISA 10256-MM06
CD64 / FCGR1A Antibody, Mouse Mab Human WB 10256-MM07
CD64 / FCGR1A Antibody, Rabbit Pab Human WB, ELISA 10256-RP01
CD64 / FCGR1A Antibody, Rabbit Pab Human WB, ELISA 10256-RP02
FCGR1 / CD64 antibody, Rabbit Pab Mouse WB, ELISA 50086-RP01
FCGR1 / CD64 antibody, Rabbit Pab(Antigen Affinity Purified) Mouse WB, ELISA 50086-RP02
FCGR1 / CD64 antibody, Rabbit Mab Mouse WB, ELISA, IHC-P 50086-R001
FCGR1 / CD64 antibody, Rabbit Mab Mouse ELISA, IHC-P 50086-R008
FCGR1 / CD64 antibody (FITC), Rabbit Mab Mouse FCM 50086-R027-F
CD64 / FCGR1A Antibody, Rabbit Pab Rat WB, ELISA 80016-RP02
CD64 / FCGR1A Antibody, Mouse Mab Rat WB, ELISA 80016-MM01
CD64 / FCGR1A Antibody, Rabbit Mab Rat ELISA 80016-R015
CD32a / FCGRA / Fc gamma RIIA Antibody, Mouse Mab Human ELISA 10374-MM01
CD32a / FCGRA / Fc gamma RIIA Antibody, Mouse Mab Human ELISA 10374-MM02
CD32a / FCGRA / Fc gamma RIIA Antibody, Mouse Mab Human WB, ELISA 10374-MM03
CD32a / FCGRA / Fc gamma RIIA Antibody, Mouse Mab Human ELISA, IHC-P 10374-MM05
CD32a / FCGRA / Fc gamma RIIA Antibody, Rabbit Pab Human WB, ELISA 10374-RP01
CD32a / FCGRA / Fc gamma RIIA Antibody, Rabbit Pab
(Antigen Affinity Purified)
Human WB, ELISA 10374-RP02
CD32a / Fc gamma RIIA Antibody, Rabbit Pab
(Antigen Affinity Purified)
Cynomolgus WB, ELISA 90015-RP02
CD32a / Fc gamma RIIA / FCGR2A Antibody,Rabbit Pab
(Antigen Affinity Purified)
Cynomolgus WB, ELISA 90016-RP02
CD32a / Fc gamma RIIA Antibody, Mouse Mab Cynomolgus WB, ELISA 90015-MM06
CD32a / Fc gamma RIIA / FCGR2A Antibody, Mouse Mab Cynomolgus WB, ELISA 90016-MM01
CD32a / Fc gamma RIIA / FCGR2A Antibody, Rabbit Mab Cynomolgus ELISA 90016-R148
CD32a / Fc gamma RIIA / FCGR2A Antibody, Rabbit Mab Cynomolgus ELISA 90016-R085
CD32b / FCGRB / Fc gamma RIIB Antibody, Rabbit Pab Human WB, ELISA 10259-RP01
CD32b / FCGRB / Fc gamma RIIB Antibody, Rabbit Pab
(Antigen Affinity Purified)
Human WB, ELISA 10259-RP03
CD32b / FCGRB / Fc gamma RIIB Antibody, Rabbit Mab Human WB, ELISA,
IHC-P, FCM
10259-R110
CD32b / FCGRB / Fc gamma RIIB Antibody, Rabbit Mab Human ELISA 10259-R112
CD32b / FCGRB / Fc gamma RIIB Antibody (FITC),
Rabbit Mab
Human FCM 10259-R112-F
CD32b / FCGRB / Fc gamma RIIB Antibody, Mouse Mab Human WB, ELISA 10259-MM02
CD32 / FCGR2B Antibody,Rabbit Pab(Antigen Affinity
Purified)
Mouse ELISA 50030-RP02
FCGR2B / CD32 Antibody, Rabbit Mab Mouse WB, ELISA 50030-R005
CD32 / FCGR2B Antibody, Rabbit Pab Mouse WB, ELISA 50030-RP01
CD32b / FCGRB/ Fc gamma RIIB Antibody, Rabbit Pab Rat WB, ELISA 80018-RP01
CD32b / FCGRB/ Fc gamma RIIB Antibody, Rabbit Pab
(Antigen Affinity Purified)
Rat ELISA, IHC-P 80018-RP02
CD32b / Fc gamma RIIB Antibody, Rabbit Pab Cynomolgus WB, ELISA 90014-RP02
CD32b / Fc gamma RIIB Antibody, Mouse Mab Cynomolgus WB, ELISA 90014-MM03
CD32b / Fc gamma RIIB Antibody, Rabbit Mab Cynomolgus ELISA 90014-R046
CD16a / FCGR3A / FcRIIIa Antibody, Mouse Mab Human WB 10389-MM01
CD16a / FCGR3A / FcRIIIa Antibody, Mouse Mab Human ELISA 10389-MM02
CD16a / FCGR3A / FcRIIIa Antibody, Mouse Mab Human ELISA 10389-MM03
CD16a / FCGR3A Antibody, Rabbit Pab Human WB, ELISA 10389-RP01
CD16a / FCGR3A Antibody, Rabbit Pab (Antigen
Affinity Purified)
Human WB, ELISA 10389-RP02
CD16a / FCGR3A Antibody, Rabbit Pab (Antigen
Affinity Purified)
Rat WB, ELISA 80017-RP02
CD16a / FCGR3A Antibody, Mouse Mab Rat WB, ELISA 80017-MM06
CD16b / FCGR3B / FcRIIIb Antibody, Rabbit Pab Human WB, ELISA 11046-RP01
CD16b / FCGR3B / FcRIIIb Antibody, Rabbit Pab (Antigen
Affinity Purified)
Human WB, ELISA 11046-RP02
CD16b / FCGR3B Antibody, Mouse Mab Human ELISA 11046-MM01
CD16b / FCGR3B Antibody, Mouse Mab Human WB 11046-MM04
CD16b / FCGR3B Antibody, Mouse Mab Human WB 11046-MM09
CD16 / FCGR3 Antibody, Rabbit Pab Mouse WB, ELISA 50326-RP01
CD16 / FCGR3 Antibody, Rabbit Pab (Antigen Affinity Purified) Mouse WB, ELISA 50326-RP02
CD16 / FCGR3 Antibody, Rabbit Pab Mouse WB, ELISA 50326-R015
CD16-2 / FCGR4 Antibody, Rabbit Pab Mouse WB, ELISA 50036-RP01
CD16-2 / FCGR4 Antibody, Rabbit Pab (Antigen
Affinity Purified)
Mouse WB, ELISA 50036-RP02
CD16-2 / FCGR4 Antibody, Rabbit Pab Mouse ELISA, ICC / IF,
FCM, IF
50036-R012
CD16-2 / FCGR4 Antibody (FITC), Rabbit Mab Mouse FCM 50036-R012-F
CD16-2 / FCGR4 Antibody, Rabbit Mab Mouse ELISA, IHC-P 50036-R011
CD16 / FCGR3 Antibody, Rabbit Pab (Antigen Affinity Purified) Cynomolgus WB, ELISA 90013-RP02
CD16 / FCGR3 Antibody, Mouse Mab Cynomolgus ELISA 90013-MM01
CD23 / FCER2 Antibody, Mouse Mab Human ELISA, IHC-P 10261-MM05
CD23 / FCER2 Antibody, Rabbit Mab Human ELISA 10261-R176
CD23 / FCER2 Antibody, Rabbit Pab Mouse WB, ELISA 50695-RP01
CD23 / FCER2 Antibody, Rabbit Pab Mouse WB, ELISA 50695-RP02
FCRL1 / FCRH1 Antibody, Rabbit Pab (Antigen
Affinity Purified)
Human WB, ELISA 11536-H08H
FCGRT/B2M Heterodimer Antibody, Mouse Mab Human ELISA CT009-MM04
FCGRT & B2M Heterodimer (FcRn)
Antibody , Rabbit Pab (Antigen Affinity Purified)
Human IHC-P CT009-RP02

Fc Receptor gene cDNA Clones back to product list

Product Name Species Cat &
Human CD89/FCAR transcript variant 1 Gene cDNA Clone / ORF Clone Human HG10414-M
Rat CD89/FCAR Gene cDNA Clone / ORF Clone Rat RG80014-M
Human CD64 Gene cDNA Clone / ORF Clone Human HG10256-M
Mouse CD64/FCGR1 Gene cDNA Clone / ORF Clone
Mouse MG50086-M
Mouse CD64 / FCGR1 ORF Expression Clone, His-tagged Mouse MG50086-M-H
Rat CD64/FCGR1 Gene cDNA Clone / ORF Clone Rat RG80016-M
Cynomolgus monkey CD64/FCGR1 Gene cDNA Clone / ORF Clone Cynomolgus CG90017-M
Human CD32a transcript variant 1 Gene cDNA Clone / ORF Clone Human HG10374-G
Mouse CD32 Gene cDNA Clone / ORF Clone
Mouse MG50030-M
Rat CD32a Gene cDNA Clone / ORF Clone Rat RG80015-M
Rat CD32a ORF Expression Clone, His-tagged Rat RG80015-M-H
Human CD32b transcript variant 3 Gene cDNA Clone / ORF Clone Human HG10259-M
Human CD32b transcript variant 2 Gene cDNA Clone / ORF Clone Human HG10260-M
Rat CD32b Gene cDNA Clone / ORF Clone Rat RG80018-M
Cynomolgus monkey CD32B Gene cDNA Clone / ORF Clone Cynomolgus CG90014-M
Cynomolgus monkey FCGR2A Gene cDNA Clone / ORF Clone Cynomolgus CG90016-M
Cynomolgus monkey FCGR3 Gene cDNA Clone / ORF Clone Cynomolgus CG90013-M
Human CD16a transcript variant 1 partial Gene cDNA Clone / ORF Clone Human HG10389-M
Mouse CD16-2 / FCGFR4 Gene cDNA Clone / ORF Clone Mouse MG50036-M
Rat CD16a Gene cDNA Clone / ORF Clone Rat RG80017-M
Rat FCER1G Gene cDNA Clone / ORF Clone Rat RG80092-G
Human FCER1A Gene cDNA Clone / ORF Clone Human HG13193-G
Mouse FCER2A Gene cDNA Clone / ORF Clone Mouse MG50695-G
Mouse FCER1A Gene cDNA Clone / ORF Clone Mouse MG50935-G
Mouse FCER1G Gene cDNA Clone / ORF Clone Mouse MG50925-G
Rat FCER1G Gene cDNA Clone / ORF Clone Rat RG80092-G
Rat FCER2 Gene cDNA Clone / ORF Clone Rat RG80208-G
Cynomolgus monkey FCER2 partial Gene cDNA Clone / ORF Clone Cynomolgus CG90150-G
Human FCRL1 Gene cDNA Clone / ORF Clone Human HG11536-M
Mouse FCRL1 Gene cDNA Clone / ORF Clone Mouse MG50947-G
Mouse FCGRT Gene cDNA Clone / ORF Clone Mouse MG50924-G
Rat FCGRT Gene cDNA Clone / ORF Clone Rat RG80094-G
Mouse FCAMR Gene cDNA Clone / ORF Clone Mouse MG51089-G
Rat FCAMR Gene cDNA Clone / ORF Clone Rat RG80095-G

 

Fc Receptor ELISA Kits back to product list

Product Name React Conjugation Cat &
CD89 / FCAR ELISA Pair Set Human HRP SEK10414
CD32b / FCGR2B ELISA Pair Set Human Biotin SEK10259
CD32b / FCGR2B ELISA Pair Set Human HRP SEKA10259
CD32a / Fc gamma RIIA / FCGR2A ELISA Pair Set Cynomolgus HRP SEK90016
CD16 / FCGR3 ELISA Pair Set Cynomolgus HRP SEK90013

 

Fc receptor Background

Fc receptor is a protein belonging to immunoglobulin superfamily that contributes to the protective functions of the immune system. Fc receptor is found on the surface of certain cells - including B lymphocytes, natural killer cells, macrophages, neutrophils and mast cells. Its name is derived from its binding specificity for a part of an antibody known as the Fc portion. Fc receptors bind to antibodies that are attached to infected cells or invading pathogens. There are many kinds of Fc receptor based on the type of antibody that they recognize. Their activity stimulates phagocytic or cytotoxic cells to destroy microbes or infected cells by antibody-mediated phagocytosis or antibody-dependent cell-mediated cytotoxicity.

Fc Receptors

What is Fc receptor

Fc receptor is a protein belonging to immunoglobulin superfamily that contributes to the protective functions of the immune system. Fc receptor can bind to fc portion of antibody. There are many kinds of Fc receptor based on the type of antibody that they recognize. More…

Fc receptor function

Fc receptors are found on a number of cells in the immune system including phagocytes like macrophages and monocytes, granulocytes like neutrophils and eosinophils and lymphocytes of the innate immune system (natural killer cells) or adaptive immune system (e.g., B cells). They allow these cells to bind antibodies that are attached to the surface of microbes or microbe infected cells, helping these cells to identify and eliminate microbial pathogens. Activation of phagocytes is the most common function attributed to Fc receptors. More…

Classes of Fc receptor

Fc receptor have been isolated and they are classified into different types based on the type of antibody that they recognize. More…

Fc alpha receptor (FCAR / FcαR)

Fc alpha receptor (FcαR) is the receptor specific for IgA which binds IgA with low affinity. There is only one type belonging to the Fc alpha receptor subgroup, which is called FcαRI (CD89/FCAR/FcαR). Fc alpha receptor I is expressed on neutrophils, eosinophils, monocytes/macrophages, dendritic cells and Kupffer cells. More…

Fc gamma receptor (FCGR / FcγR)

Fc gamma receptor (FcγR) is a receptor for the Fc portion of IgG. There are three major classes of Fc gamma receptor receptors. For example, CD64 (FCGRI / FcγRI), CD32 (FCGRII / FcγRII), CD16 (FCGRIII / FcγRIII). All of the Fc gamma receptors (FcγR) belong to the immunoglobulin superfamily. Fc gamma receptor is essential participant in many immune system effector functions, such as phagocytosis of opsonized, release of inflammatory mediators and antibody-dependent cellular cytotoxicity. More…

Fc epsilon receptor (FCER / FcεR)

Fc epsilon receptor (FcεR) is a Fc receptor that binding IgE. There are two classes of FcεRs on cells of the immune system. The high-affinity receptor, Fc epsilon receptor I (FcεRI / FCERI), which is capable of binding monomeric IgE. The low-affinity receptor, Fc epsilon receptor II (FcεRII / CD23 / FCERII) which interacts preferentially with complex IgE. More…

Neonatal Fc receptor (FCGRT)

Neonatal Fc receptor is kind of MHC class-I receptor. The neonatal Fc receptor (FCGRT) was first discovered in rodents. Further studies revealed a similar receptor in humans. In rodents, neonatal Fc receptor in the neonatal gut epithelium and fetal yolk sac transports maternal IgG to the neonate and in humans neonatal Fc receptor mediates maternal-fetal IgG transport across the placenta. More…

Fc Receptor-Like protein (FCRL / FCRH)

FCRL is a Fc Receptor-Like protein and is a subfamily of the five Ig superfamily members. FCRL is also called Fc Receptor Homolog (FCRH). The genes of FCRLs locate on human chromosome 1 and mouse chromosome 3. The genes of FCRLs have also been identified as immunoglobulin superfamily receptor translocation associated (IRTA) genes, SH-2 domain-containing phosphatase anchor proteins (SPAP) genes. FCRLs have sequence homology with the classical Fc receptor for IgG, FCGRI, FCGRII and FCGRIII. Members of FcRH1-5 subfamily belong to the network of receptors that possess immunoreceptor tyrosinebased activating motifs (ITAM), inhibition motifs (ITIM) or both. Their functions are as an activating coreceptor in B-cells and promoting B-cells activation and differentiation. More…

Fcα/μR (FCAMR)

Fcα/μ receptor (Fcα/μR) is a novel Fc receptor for IgM and IgA (FCAMR), designated, which might be involved in IgM-mediated immune defenses against infection. Fcα/μR is a new member of Fc receptors, whose gene is closely located at the polymeric immunoglobulin receptor (poly-IgR) in the Fc receptor gene cluster on the chromosome 1. The Fcα/μR is constitutively expressed on the majority of B-lymphocytes and macrophages in the spleen and at the center of the secondary lymphoid follicles. The Fcα/μR mediates endocytosis immune complexes of Staphylococcus aureus/anti-S. aureus IgM antibody by B-lymphocytes. These results reveal a new mechanism in the primary stage of immune defense against microbes. More…

 

Fc receptor Related Studies

    1. Marc Da eron, et al. (1997) Annu. Rev. Immunol. 15:203-34.
    2. R. Jefferis, et al. (2002) Immunology Letters.82:57-65.
    3. Robert L. Shields, et al. (2001) The Journal Of Biological Chemistry. 276(9):6591-6604.
    4. Yi Ding, et al. (2003) The Journal Of Biological Chemistry.278(30):27966-27970
    5. D. von Bubnoff, et al. (2003) Clinical and Experimental Dermatology28:184-187.
    6. E.J.Tsrael, et al. (1997) Immunology92:69-74.
    7. H.Craig Morton, et al. (2001) Archivum Immunologiae et Therapiae Experimentalis49:217-229.
    8. J.E.Gessner, et al. (1998) Ann Hematol 76:231-248.
    9. Peter Sondermann, et al. (1999) The EMBO Journal18(5):1095-1103.
    10. Ofer Mandelboim, et al. (1999) Immunology96:5640-5644.
    11. Richard G, et al. (2005) Clinical and Experimental Dermatology28:184-187.
    12. Andrew G, et al. (2006) International Immunology18(9):1363-1373.
    13. S. Honda, et al. (2005) International Congress Series1285:78-83.

     

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