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> FSTL1 Protein & Antibody FSTL1 Protein & Antibody
Follistatin Like 1
FSTL1 Products
FSTL1 Protein, Recombinant
| Molecule | Species | Description //For Detailed Info. and Price------CLICK! | Cat. No |
| FSTL1/Follistatin Like 1 | Human | FSTL1 Protein, Recombinant | 10924-H08H |
FSTL1 Antibody
| Molecule | Application | Description //For Detailed Info. and Price------CLICK! | Cat. No |
| Human FSTL1/Follistatin Like 1 |
WB, ELISA | Rabbit Polyclonal Antibody | 10924-RP01 |
| Human FSTL1/Follistatin Like 1 |
WB, ELISA | Rabbit Polyclonal Antibody (Antigen Affinity Purified) | 10924-RP02 |
FSTL1 cDNA Clone
| Molecule | Species | Description //For Detailed Info. and Price------CLICK! | Cat. No |
| FSTL1/Follistatin Like 1 | Human | Homo sapiens FSTL1 cDNA Clone(NM_007085.4) | HG10924-M |
FSTL1 Alternative Names
FSTL1, FSL1, FLJ50214, FLJ52277, FRP [Homo sapiens]
Fstl1, Fstl, AI316791, AW107808, TSC-36 [Mus musculus]
FSTL1 Related Areas
Cancer>>Growth Factor & Receptor>>TGF-beta Superfamily>>Activin/Inhibitin>>FSTL1/Follistatin Like 1
Immunology>>Cytokine & Receptor>>TGF-beta Superfamily>> TGF-beta Superfamily Modulators>>FSTL1/Follistatin Like 1
FSTL1 Related Products
| Molecule | Species | Description //For Detailed Info. and Price------CLICK! |
| Inhibin beta A/INHBA | Human | Inhibin beta A/INHBA Protein, Recombinant |
| Inhibin beta B/INHBB | Human | Inhibin beta B/INHBB Protein, Recombinant |
| ALK-2/ACVR1 | Human | ALK-2/ACVR1/Fc Protein, Recombinant |
| ALK-2/ACVR1 | Mouse | ALK-2/ACVR1/Fc Protein, Recombinant |
| ACVR2A | Human | ACVR2A/Fc Protein, Recombinant |
| ACVR2B | Human | ACVR2B/Fc Protein, Recombinant |
| ACVR2B | Human | ACVR2B Protein, Recombinant |
| ACVR2B | Human | ACVR2B/Fc Protein, Recombinant |
| ACVR2B | Mouse | ACVR2B Protein, Recombinant |
| FLRG/FSTL3 | Mouse | FLRG/FSTL3 Protein, Recombinant |
| Molecule | Species | Description //For Detailed Info. and Price------CLICK! |
| Inhibin alpha/INHA | Human | Homo sapiens Inhibin alpha/INHA cDNA Clone(NM_002191.2) |
| Inhibin beta A/INHBA | Human | Homo sapiens Inhibin beta A/INHBA cDNA Clone(NM_002192.2) |
| Inhibin beta B/INHBB | Human | Homo sapiens Inhibin beta B/INHBB cDNA Clone(NM_002193.2) |
| Inhibin beta C/INHBC | Human | Homo sapiens Inhibin beta C/INHBC cDNA Clone(NM_005538.2) |
| Inhibin beta E/INHBE | Human | Homo sapiens Inhibin beta E/INHBE cDNA Clone(NM_031479.3) |
| ALK-2/ACVR1 | Human | Homo sapiens ALK-2/ACVR1 transcript variant 2 cDNA Clone(NM_001111067.2) |
| ALK-4/ACVR1B | Human | Homo sapiens ALK-4/ACVR1B cDNA Clone(NM_004302.3) |
| ACVR2A | Human | Homo sapiens ACVR2A cDNA Clone(NM_001616.3) |
| ACVR2B | Human | Homo sapiens ACVR2B cDNA Clone(NM_001106.3) |
| Follistatin | Human | Homo sapiens Follistatin cDNA Clone(NM_013409.1) |
FSTL1 Background
Follistatin-related protein 1 (FSTL1) is an extracellular glycoprotein whose functional significance in physiological and pathological processes is incompletely understood. Recently, we have shown that FSTL1 acts as a muscle-derived secreted factor that is up-regulated by Akt activation and ischemic stress and that FSTL1 exerts favorable actions on the heart and vasculature. Here, we sought to identify the receptor that mediates the cellular actions of FSTL1. It contains an FS module, a follistatin-like sequence containing 10 conserved cysteine residues. FSTL1 is thought to be an autoantigen associated with rheumatoid arthritis. DIP2A functions as a novel receptor that mediates the cardiovascular protective effects of FSTL1. Experiment results have provided in vivo and in vitro evidence to demonstrate that Fstl1 modulates lung development and alveolar maturation, in part, through BMP4 signaling.
FSTL1 Related Studies
- Rosenberg MI, et al. (2006) MyoD inhibits Fstl1 and Utrn expression by inducing transcription of miR-206. J Cell Biol. 175(1): 77-85.
- Ouchi N, et al. (2010) DIP2A functions as a FSTL1 receptor. J Biol Chem. 285(10): 7127-34.
- Geng Y, et al. (2011) Follistatin-like 1 (Fstl1) is a bone morphogenetic protein (BMP) 4 signaling antagonist in controlling mouse lung development. Proc Natl Acad Sci U S A. 108(17): 7058-63.
