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FKBP3  Protein, Antibody, ELISA Kit, cDNA Clone

Expression host: E. coli  
12582-H09E-20
12582-H09E-100
20 µg 
100 µg 
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  • Slide 1

FKBP3 Related Area

FKBP3 Related Pathways

    FKBP3 Summary & Protein Information

    FKBP3 Background

    Gene Summary: The protein encoded by this FKBP3 gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. FKBP3 is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. FKBP3 has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin. [provided by RefSeq, Sep 2008]
    General information above from NCBI
    Catalytic activity: Peptidylproline (omega=180) = peptidylproline (omega=0).
    Cofactor: 0
    Enzyme regulation: Inhibited preferentially by rapamycin over FK506.
    Subunit structure: Nucleus.
    Domain: 0
    Subcellular location: Nucleus.
    Tissue specificity: 0
    Developmental stage: 0
    Induction: 0
    Post-translational: 0
    Involvement in disease: 0
    Sequence similarity: Belongs to the FKBP-type PPIase family. {ECO:0000305}.; Contains 1 PPIase FKBP-type domain. {ECO:0000255|PROSITE-ProRule:PRU00277}.
    General information above from UniProt

    FKBP3 Alternative Name

    PPIASE,FKBP-3,FKBP25,FKBP-25, [homo-sapiens]
    FKBP25,PPIase,FKBP-25,FKBP3, [human]
    25kDa,FKBP25,FKBP-3,Fkbp3, [mouse]
    25kDa,FKBP-3,FKBP25, [mus-musculus]

    FKBP3 Related Studies

  • Wiederrecht G., et al., 1992, Biochem. Biophys. Res. Commun. 185: 298 - 303.
  • Dephoure N., et al.,2008, Proc. Natl. Acad. Sci. USA.105:10762-7.
  • Gauci S., et al., 2009, Anal. Chem. 81:4493-4501.
  • Choudhary C., et al., 2009, Science. 325:834-840.
  • Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"