FIGF Protein & Antibody (VEGF-D, VEGFD)

C-fos Induced Growth Factor (Vascular Endothelial Growth Factor D)

FIGF Products

FIGF Protein, Recombinant

Molecule	Species	Description	Cat. No
FIGF/VEGF-D	Human	FIGF/VEGF-D Protein, Recombinant	10557-H08H
FIGF/VEGF-D	Mouse	VEGF-D / VEGFD / FIGF Protein, Recombinant	50157-M01H

FIGF Antibody

Molecule	Application	Description	Cat. No
Human FIGF/VEGF-D	ELISA	Rabbit Monoclonal Antibody	10557-R106
Human FIGF/VEGF-D	WB, ELISA	FIGF/VEGF-D Antibody, Rabbit MAb	10557-R201
Human FIGF/VEGF-D	WB, ELISA	Rabbit Polyclonal Antibody (Antigen Affinity Purified)	10557-RP01
Human FIGF/VEGF-D	WB, ELISA	Rabbit Polyclonal Antibody	10557-RP02

FIGF cDNA Clone

Molecule	Species	Description	Cat. No
FIGF/VEGF-D	Human	Homo sapiens FIGF/VEGF-D cDNA Clone	HG10557-M
FIGF/VEGF-D	Mosue	Mus musculus FIGF/VEGF-D cDNA Clone	MG50157-M
FIGF/VEGF-D	Rat	FIGF cDNA Clone / ORF Clone	RG80104-G

FIGF Alternative Names

VEGF-D, VEGFD [Homo sapiens]

RP23-202H24.2, AI325264, VEGF-D, Vegfd [Mus musculus]

Vegf-d [Rattus norvegicus]

FIGF Related Areas

Cancer>>Growth factor & Receptor>>VEGF & Receptor>>FIGF/VEGF-D

FIGF Protein Related Products

Protein Products

Molecule	Species	Description
Neuropilin-1	Human	Neuropilin-1/NRP1/Fc Protein, Recombinant
PDGF-C	Human	PDGF-C/Fc Protein, Recombinant
PDGF-D	Human	PDGF-D/Fc Protein, Recombinant
PDGFRA/CD140a	Human	PDGFRA/CD140a/Fc Protein, Recombinant
PDGFRA/CD140a	Human	PDGFRA/CD140a Protein, Recombinant
PDGFRA/CD140a	Human	PDGFRA/CD140a Protein, Recombinant
VEGF/VEGF-A	Human	VEGF 121 Protein, Recombinant
VEGF/VEGF-A	Human	VEGF 165 Protein, Recombinant
VEGF/VEGF-A	Human	VEGF 183 Protein, Recombinant
VEGF-C	Human	VEGF-C Protein, Recombinant
VEGFR1/FLT-1	Human	VEGFR1/FLT-1 Protein, Recombinant
VEGFR3/FLT-4	Human	VEGFR3/FLT-4/Fc Protein, Recombinant
VEGFR3/FLT-4	Human	VEGFR3/FLT-4 Protein, Recombinant
VEGFR3/FLT-4	Mouse	VEGFR3/FLT-4/Fc Protein, Recombinant
VEGFR3/FLT-4	Mouse	VEGFR3/FLT-4 Protein, Recombinant

Antibody Products

Molecule	Application	Description
Human PDGFRA/CD140a	ELISA	Mouse Monoclonal Antibody
Human PDGFRA/CD140a	WB, ELISA	Rabbit Monoclonal Antibody
Human PDGFRA/CD140a	WB, ELISA	Rabbit Polyclonal Antibody
Human PDGFRA/CD140a	WB, ELISA	Rabbit Polyclonal Antibody (Antigen Affinity Purified)
Human VEGF/VEGF-A	WB, ELISA	VEGF/VEGF-A Antibody, Rabbit PAb
Human VEGF/VEGF-A	WB, ELISA	VEGF/VEGF-A Antibody, Rabbit PAb (Antigen Affinity Purified)
Human VEGF-C/VEGFC	WB, ELISA	Rabbit Polyclonal Antibody
Human VEGF-C/VEGFC	WB, ELISA	Rabbit Polyclonal Antibody (Antigen Affinity Purified)
Human VEGFR3/FLT-4	WB	Mouse Monoclonal Antibody
Human VEGFR3/FLT-4	ELISA	Mouse Monoclonal Antibody
Human VEGFR3/FLT-4	ELISA	Rabbit Polyclonal Antibody
Human VEGFR3/FLT-4	WB, ELISA	Rabbit Polyclonal Antibody (Antigen Affinity Purified)

cDNA Clone Products

Molecule	Species	Description
Neuropilin-1	Human	Homo sapiens Neuropilin-1 transcript variant 2 cDNA Clone(NM_001024628.2)
PDGF-B	Human	Homo sapiens PDGF-B cDNA Clone(NM_002608.2)
PDGF-C	Human	Homo sapiens PDGF-C cDNA Clone(NM_016205.1)
PDGF-D	Human	Homo sapiens PDGF-D transcript variant 1 cDNA Clone(NM_025208.4)
PDGFRA/CD140a	Human	Homo sapiens PDGFRA/CD140a cDNA Clone(NM_006206.4)
PGF/PLGF	Human	Homo sapiens PGF/PLGF cDNA Clone(NM_002632.4)
VEGF/VEGF-A	Human	Homo sapiens VEGF/VEGF-A transcript variant 6 cDNA Clone(NM_001025370.1)
VEGF/VEGF-A	Human	Homo sapiens VEGF/VEGF-A transcript variant 3 cDNA Clone(NM_001025367.1)
VEGF/VEGF-A	Human	Homo sapiens VEGF/VEGF-A transcript variant 2 cDNA Clone(NM_003376.4)
VEGF/VEGF-A	Mouse	Mus musculus VEGF/VEGF-A cDNA Clone
VEGF/VEGF-A	Canine	Canis lupus familiars VEGF/VEGF-A cDNA Clone
VEGF-B	Human	Homo sapiens VEGF-B cDNA Clone(NM_003377.3)
VEGF-B	Mouse	Mus musculus VEGF-B cDNA Clone
VEGF-C	Human	Homo sapiens VEGF-C cDNA Clone(NM_005429.2)
VEGF-C	Mouse	Mus musculus VEGF-C cDNA Clone
VEGFR1/FLT-1	Human	Human VEGFR1/FLT-1 cDNA Clone / ORF Clone
VEGFR3/FLT-4	Human	Homo sapiens VEGFR3/FLT-4 cDNA Clone

FIGF Background

Vascular endothelial growth factor D (VEGF-D), also known as C-fos induced growth factor (FIGF), belongs to the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family. FIGF protein is active in angiogenesis, lymphangiogenesis, and endothelial cell growth. FIGF protein is secreted as a non-covelent homodimer in an antiparallel fashion. Human FIGF protein is expressed in adult lung, heart, muscle, and small intestine, and is most abundantly expressed in fetal lungs and skin. FIGF protein is structurally and functionally similar to VEGF-C. Therefore, FIGF protein binds and activates VEGFR-2 (Flk1) and VEGFR-3 (Flt4) receptors, and may particularly be involved in cancers, such as breast cancer, epithelial ovarian carcinoma and so on.

FIGF Related Studies

1. Avantaggiato V, et al. (1998) Embryonic expression pattern of the murine figf gene, a growth factor belonging to platelet-derived growth factor/vascular endothelial growth factor family. Mech Dev. 73(2):221-4.
2. Rocchigiani M, et al. (1998) Human FIGF: cloning, gene structure, and mapping to chromosome Xp22.1 between the PIGA and the GRPR genes. Genomics 47(2):207-16.
3. Karpanen T, et al. (2008) VEGF-D: a modifier of embryonic lymphangiogenesis. Blood. 112(5): 1547-8.