Anti-VEGFD Antibody

Cat: 10557-RP02
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Anti-VEGFD Antibody (Rabbit Polyclonal antibody) General Information
Product name
Anti-VEGFD Antibody
Validated applications
ELISA
Species reactivity
Reacts with: Human
Specificity
Human VEGFD
Immunogen
Recombinant Human VEGF-D protein (Catalog#10557-H08H)
Preparation
Produced in rabbits immunized with purified, recombinant Human VEGF-D (rh VEGF-D; Catalog#10557-H08H; NP_004460.1; Phe 93-Ser 201). Total IgG was purified by Protein A affinity chromatography .
Source
Polyclonal Rabbit IgG
Purification
Protein A
Formulation
0.2 μm filtered solution in PBS with 5% trehalose
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-VEGFD Antibody (Rabbit Polyclonal antibody) Validated Applications
Application Dilution Notes
ELISA 1:1000-1:2000  

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-VEGFD Antibody Alternative Names
Anti-VEGF-D Antibody;Anti-VEGFD Antibody
VEGFD Background Information

Vascular endothelial growth factor D (VEGF-D), also known as C-fos induced growth factor (FIGF), belongs to the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family. FIGF protein is active in angiogenesis, lymphangiogenesis, and endothelial cell growth. FIGF protein is secreted as a non-covelent homodimer in an antiparallel fashion. Human FIGF protein is expressed in adult lung, heart, muscle, and small intestine, and is most abundantly expressed in fetal lungs and skin. FIGF protein is structurally and functionally similar to VEGF-C. Therefore, FIGF protein binds and activates VEGFR-2 (Flk1) and VEGFR-3 (Flt4) receptors, and may particularly be involved in cancers, such as breast cancer, epithelial ovarian carcinoma and so on.

Full Name
c-fos induced growth factor (vascular endothelial growth factor D)
References
  • Avantaggiato V, et al. (1998) Embryonic expression pattern of the murine figf gene, a growth factor belonging to platelet-derived growth factor/vascular endothelial growth factor family. Mech Dev. 73(2):221-4.
  • Rocchigiani M, et al. (1998) Human FIGF: cloning, gene structure, and mapping to chromosome Xp22.1 between the PIGA and the GRPR genes. Genomics 47(2):207-16.
  • Karpanen T, et al. (2008) VEGF-D: a modifier of embryonic lymphangiogenesis. Blood. 112(5): 1547-8.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-VEGFD Antibody Rabbit Polyclonal ELISA 10557-T16
    Anti-VEGFD Antibody Rabbit Monoclonal ELISA 10557-R106
    Anti-VEGFD Antibody Rabbit Monoclonal ELISA 10557-R201
    Anti-VEGFD Antibody Mouse Monoclonal ELISA 10557-MM15
    Anti-VEGFD Antibody Rabbit Polyclonal ELISA 10557-RP01
    info info
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