FGFBP3 Protein Price Inquiry ( Available Sizes )
FGFBP3 Protein Product Information
||A DNA sequence encoding the human FGFBP3 ( Met 1- Gly 258) (Q8TAT2) was expressed, with a C-terminal polyhistidine tag.
FGFBP3 Protein QC Testing
||> 87 % as determined by SDS-PAGE
||< 1.0 EU per μg of the protein as determined by the LAL method
||Samples are stable for up to twelve months from date of receipt at -70℃
|Predicted N terminal:
||The secreted recombinant human FGFBP3 consists of 243 amino acids and predicts a molecular mass of 26.4 KDa. The apparent molecular mass of the protein is approximately 33 Kda in SDS-PAGE under reducing conditions due to glycosylation.
||Lyophilized from sterile 20mM Tris, 500mM NaCl, 10% gly, pH7.4.
- Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
- Please contact us for any concerns or special requirements.
FGFBP3 Protein Usage Guide
||Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
||A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
FGFBP3 Protein Related Products & Topics
FGFBP3 Protein Description
FGFBP3 is a member of the fibroblast growth factor-binding protein family. Fibroblast growth factors (FGFs) play an important role in the regulation of cell migration, proliferation and differentiation. The fibroblast growth factor-binding protein (FGF-BP) binds and activates FGF-1 and FGF-2, thereby contributing to tumor angiogenesis. After injury to murine and human skin, the expression of FGF-BP is increased, especially in keratinocytes. It is generally thought that this upregulation is achieved by major keratinocyte mitogens present at the wound site. FGFBP3 is a protein that exhibits fibroblast growth factor binding (orthology) and heparin binding (orthology). It is found that FGFBP3 is a positive regulator of fibroblast growth factor receptor signaling pathway and vascular permeability. It interacts with 2,3,7,8-tetrachlorodibenzodioxine, benzopyrene and valproic acid.
- Abuharbeid S. et al., 2006, Int J Biochem Cell Biol. 38 (9): 1463-8.
- Lange LG. et al., 1976, Biochemistry. 15 (21): 4687-93.
- Czubayko F. et al., 1997, Nat Med. 3 (10): 1137-40.