FGFBP3 Protein

Fibroblast growth factor binding protein 3

FGFBP3 Products

FGFBP3 Protein, Recombinant

Molecule	Species	Description //For Detailed Info. and Price------CLICK!	Cat No
FGFBP3	Human	FGFBP3 Protein, Recombinant	10986-H08B

FGFBP3 cDNA Clone

Molecule	Species	Description //For Detailed Info. and Price------CLICK!	Cat No
FGFBP3	Human	Human FGFBP3 Gene cDNA Clone / ORF Clone	HG10986-M

FGFBP3 Related Areas

Cancer>>Growth Factor & Receptor>>FGFBP3

FGFBP3 Alternative Names

PSEC0101, C10orf13, FGF-BP3, MGC39320, FGF-binding protein 3, FGFBP-3, fibroblast growth factor-binding protein 3 [Homo sapiens]

2610306H15Rik, Fgf-bp3, FGF-binding protein 3, FGFBP-3, fibroblast growth factor-binding protein 3 [Mus musculus]

FGFBP3 Background

FGFBP3 is a member of the fibroblast growth factor-binding protein family. Members of this family binds and activates FGF-1 and FGF-2, thereby contributing to tumor angiogenesis. Fibroblast growth factors (FGFs) are important regulators of cell migration, proliferation and differentiation, e.g., during embryogenesis and wound healing, and under several pathological conditions including tumor growth and tumor angiogenesis. Expression of FGF-BP increases after injury to murine and human skin, in particular in keratinocytes. This upregulation is most likely achieved by major keratinocyte mitogens present at the wound site. FGFBP3 is a positive regulator of fibroblast growth factor receptor signaling pathway and vascular permeability. It interacts with 2,3,7,8-tetrachlorodibenzodioxine, benzopyrene and valproic acid. FGFBP3 also exhibits fibroblast growth factor binding (orthology) and heparin binding (orthology).

FGFBP3 Related Studies

1. Abuharbeid S, et al. (2006) The fibroblast growth factor-binding protein FGF-BP. Int J Biochem Cell Biol. 38(9):1463-8.
2. Lange LG, et al. (1976) Human liver alcohol dehydrogenase: purification, composition, and catalytic features. Biochemistry. 15(21):4687-93.
3. Czubayko F, et al. (1997) A secreted FGF-binding protein can serve as the angiogenic switch in human cancer. Nat Med. 3(10):1137-40.