All FGF10 reagents are produced in house and quality controlled, including 7 FGF10 Antibody, 1 FGF10 ELISA, 47 FGF10 Gene, 1 FGF10 IPKit, 1 FGF10 Protein, 2 FGF10 qPCR. All FGF10 reagents are ready to use.
Recombinant FGF10 proteins are expressed by E. coli with fusion tags as Native.
FGF10antibodies are validated with different applications, which are ELISA(Cap), WB, IHC-P, IP, ELISA.
FGF10cDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each FGF10 of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.
FGF10ELISA Kit are quality controlled by 8 internation QC standard which guarantee every ELISA Kit with high quality.
Fibroblast growth factor 10 (FGF10) is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF10 exhibits mitogenic activity for keratinizing epidermal cells, but essentially no activity for fibroblasts, which is similar to the biological activity of FGF7. FGF10 plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation. FGF10 is required for normal branching morphogenesis. It may play a role in wound healing. Defects in FGF10 are the cause of autosomal dominant aplasia of lacrimal and salivary glands (ALSG). ALSG has variable expressivity, and affected individuals may have aplasia or hypoplasia of the lacrimal, parotid, submandibular and sublingual glands and absence of the lacrimal puncta. The disorder is characterized by irritable eyes, recurrent eye infections, epiphora (constant tearing) and xerostomia (dryness of the mouth), which increases the risk of dental erosion, dental caries, periodontal disease and oral infections.