FDPS cDNA ORF Clone in Cloning Vector, Rat

Cat: RG80771-U
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FDPS cDNA ORF Clone in Cloning Vector, Rat General Information
Gene
Species
Rat
NCBI Ref Seq
RefSeq ORF Size
1062 bp
Sequence Description
Identical with the Gene Bank Ref. ID sequence.
Description
Full length Clone DNA of Rat farnesyl diphosphate synthase.
Plasmid
Vector
pUC19 Vector
Sequencing Primers
M13-47 and RV-M
Quality Control
The plasmid is confirmed by full-length sequencing.
Screening
Antibiotic in E.coli
Ampicillin
Storage & Shipping
Shipping
Each tube contains lyophilized plasmid.
Storage
The lyophilized plasmid can be stored at ambient temperature for three months.
FDPS cDNA ORF Neucleotide Sequence and Amino Acid Sequence Information

**Sino Biological guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories.**

FDPS cDNA ORF Clone in Cloning Vector, Rat Validated Images
Cynomolgus GEMIN8 Gene Plasmid Map 7146
FDPS Background Information

Z-farnesyl diphosphate synthase (FDPS) is an enzyme belonging to the family of transferases, specifically those transferring aryl or alkyl groups other than methyl groups. Z-farnesyl diphosphate synthase (FDPS) functions as key enzyme in isoprenoid biosynthesis which catalyzes the formation of farnesyl diphosphate, a precurcor for several classes of essential metabolites. FDPS catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein farnesylation and geranylgeranylation, and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption. Functions of FDPS may be inactivated by interferon-induced RSAD2. This inactivation may result of disruption of lipid rafts at the plasma membrane, and thus have an antiviral effect since many enveloped viruses need lipid rafts to bud efficiently out of the cell.

Full Name
farnesyl diphosphate synthase
References
  • Pjetursson BE, et al. (2007) Comparison of survival and complication rates of tooth-supported fixed dental prostheses (FDPs) and implant-supported FDPs and single crowns (SCs). Clin Oral Implants Res. 3:97-113.
  • Eschbach S, et al. (2009) Clinical evaluation of all-ceramic posterior three-unit FDPs made of In-Ceram Zirconia. Int J Prosthodont. 22(5):490-2.
  • Moshage HJ, et al. (1990) Differential effects of endotoxin and fibrinogen degradation products (FDPS) on liver synthesis of fibrinogen and albumin: evidence for the involvement of a novel monokine in the stimulation of fibrinogen synthesis induced by FDPS. Int J Biochem. 22(12): 1393-400.
  • FDPS cDNA ORF Clone, Rat, Related Products

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    FDPS cDNA ORF Clone, Rat, untagged RG80771-UT
    FDPS Lentiviral cDNA ORF Clone, Rat, C-GFPSpark® tag RG80771-ACGLN
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    FDPS cDNA ORF Clone, Rat, N-GFPSpark® tag RG80771-ANG
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    FDPS cDNA ORF Clone, Rat, C-His tag RG80771-CH
    FDPS cDNA ORF Clone, Rat, N-His tag RG80771-NH
    FDPS cDNA ORF Clone, Rat, C-HA tag RG80771-CY
    FDPS cDNA ORF Clone, Rat, N-HA tag RG80771-NY
    FDPS cDNA ORF Clone, Rat, C-Myc tag RG80771-CM
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    FDPS cDNA ORF Clone, Mouse, Related Products

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    FDPS cDNA ORF Clone in Cloning Vector, Mouse MG51224-U
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    FDPS cDNA ORF Clone, Mouse, C-DDK (Flag®) tag MG51224-CF
    FDPS cDNA ORF Clone, Mouse, N-DDK (Flag®) tag MG51224-NF
    FDPS cDNA ORF Clone, Mouse, C-His tag MG51224-CH
    FDPS cDNA ORF Clone, Mouse, N-His tag MG51224-NH
    FDPS cDNA ORF Clone, Mouse, C-HA tag MG51224-CY
    FDPS cDNA ORF Clone, Mouse, N-HA tag MG51224-NY
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    FDPS cDNA ORF Clone, Human, Related Products

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    FDPS cDNA ORF Clone in Cloning Vector, Human HG13229-G
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    FDPS cDNA ORF Clone, Human, N-GFPSpark® tag HG13229-ANG
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    FDPS cDNA ORF Clone, Human, N-OFPSpark® tag HG13229-ANR
    FDPS cDNA ORF Clone, Human, C-DDK (Flag®) tag HG13229-CF
    FDPS cDNA ORF Clone, Human, N-DDK (Flag®) tag HG13229-NF
    FDPS cDNA ORF Clone, Human, C-His tag HG13229-CH
    FDPS cDNA ORF Clone, Human, N-His tag HG13229-NH
    FDPS cDNA ORF Clone, Human, C-HA tag HG13229-CY
    FDPS cDNA ORF Clone, Human, N-HA tag HG13229-NY
    FDPS cDNA ORF Clone, Human, C-Myc tag HG13229-CM
    FDPS cDNA ORF Clone, Human, N-Myc tag HG13229-NM
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