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Mouse FCRL1 / FCRH1 Protein (His Tag)

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FCRL1Protein Product Information
Synonym:FCRL1, Fcrh1, Ifgp1
Protein Construction:A DNA sequence encoding the mouse FCRL1 (Q8R4Y0-2) (Met1-Thr204) was expressed with a C-terminal polyhistidine tag.
Species:Mouse
Expressed Host:Human Cells
Form & Shipping:In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
FCRL1Protein QC Testing
Purity:> 95 % as determined by SDS-PAGE
Endotoxin:< 1.0 EU per μg of the protein as determined by the LAL method
Stability:Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N Terminal:Ala 17
Formulation:Lyophilized from sterile PBS, pH 7.4
1. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
2. Please contact us for any concerns or special requirements.
Molecule Mass:The recombinant mouse FCRL1 comprises 199 amino acids and has a predicted molecular mass of 21.6 kDa. The apparent molecular mass of the protein is approximately 42-47 kDa in SDS-PAGE under reducing conditions due to glycosylation.
FCRL1Protein Usage Guide
Storage:Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution:A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
Image
Mouse FCRL1 / FCRH1 Protein (His Tag) SDS-PAGE

50947-M08H
Background

Fc receptor-like protein 1, also known as FcR-like protein 1, Fc receptor homolog 1, IFGP family protein 1, Immune receptor translocation-associated protein 5 and FCRL1, is a single-pass type I  membrane protein which contains three Ig-like C2-type (immunoglobulin-like) domains. It is a cell-surface membrane protein belonging to FCRL family and is preferentially expressed on B cells. FCRL1 is primarily expressed in secondary lymphoid tissues by mature subsets of B cells. It is detected in spleen, lymph node, heart, skeletal muscle, kidney, liver and placenta. FCRL1 is specifically expressed by mature B lineage cells with higher expression in naive versus memory B cells (at protein level). Human Fc receptor-like molecules (FCRL1, FCRL2, FCRL3, FCRL4, FCRL5) have tyrosine-based immunoregulatory potential and are expressed by B-lineage subpopulations. FCRL1 may function as an activating coreceptor in B cells. It may also function in B cells activation and differentiation.

References
  • Du X. et al., 2008, Blood. 111 (1): 338-43.
  • Kazemi T. et al., 2008, Int J Cancer. 123 (9): 2113-9.
  • Baranov K. et al., 2008, J Immunol Methods. 332 (1-2): 73-81.
  • Mouse FCRL1 / FCRH1 Protein (His Tag) on other vectors Mouse FCRL1 / FCRH1 Protein (His Tag) on other vectors
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    Catalog:50947-M08H-50
    List Price: $170.00  (Save $0.00)
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    • Mouse FCRL1 / FCRH1 Protein (His Tag) SDS-PAGE
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