FCRL1 Protein, Mouse, Recombinant (His Tag)

Cat: 50947-M08H
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FCRL1 Protein, Mouse, Recombinant (His Tag) Product Information
Purity
> 95 % as determined by SDS-PAGE
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method
Activity
Testing in progress
Protein Construction
A DNA sequence encoding the mouse FCRL1 (Q8R4Y0-2) (Met1-Thr204) was expressed with a C-terminal polyhistidine tag.
Reference#
Expressed Host
HEK293 Cells
Species
Mouse
Predicted N Terminal
Ala 17
Molecule Mass
The recombinant mouse FCRL1 comprises 199 amino acids and has a predicted molecular mass of 21.6 kDa. The apparent molecular mass of the protein is approximately 42-47 kDa in SDS-PAGE under reducing conditions due to glycosylation.
Formulation
Lyophilized from sterile PBS, pH 7.4
1. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
2. Please contact us for any concerns or special requirements.
Shipping
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Stability & Storage
Samples are stable for up to twelve months from date of receipt at -70℃
Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution
A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
FCRL1 Protein, Mouse, Recombinant (His Tag) in SDS-PAGE
Mouse FCRL1/FCRH1 Protein 11982
FCRL1 Protein, Mouse, Recombinant (His Tag) Alternative Names
A230020G22Rik Protein, Mouse;Bxmas1 Protein, Mouse;Bxmh1 Protein, Mouse;Bxmh1b Protein, Mouse;Fcrh1 Protein, Mouse;Fcrh1l Protein, Mouse;Fcrh1s Protein, Mouse;Ifgp1 Protein, Mouse
FCRL1 Background Information

Fc receptor-like protein 1, also known as FcR-like protein 1, Fc receptor homolog 1, IFGP family protein 1, Immune receptor translocation-associated protein 5 and FCRL1, is a single-pass type I  membrane protein which contains three Ig-like C2-type (immunoglobulin-like) domains. It is a cell-surface membrane protein belonging to FCRL family and is preferentially expressed on B cells. FCRL1 is primarily expressed in secondary lymphoid tissues by mature subsets of B cells. It is detected in spleen, lymph node, heart, skeletal muscle, kidney, liver and placenta. FCRL1 is specifically expressed by mature B lineage cells with higher expression in naive versus memory B cells (at protein level). Human Fc receptor-like molecules (FCRL1, FCRL2, FCRL3, FCRL4, FCRL5) have tyrosine-based immunoregulatory potential and are expressed by B-lineage subpopulations. FCRL1 may function as an activating coreceptor in B cells. It may also function in B cells activation and differentiation.

Full Name
Fc receptor-like 1
References
  • Du X. et al., 2008, Blood. 111 (1): 338-43.
  • Kazemi T. et al., 2008, Int J Cancer. 123 (9): 2113-9.
  • Baranov K. et al., 2008, J Immunol Methods. 332 (1-2): 73-81.
  • Other FCRL1 Proteins

    Human FCRL1 Proteins

    Product Name Cat.No.
    FCRL1 Protein, Human, Recombinant (His Tag) 11536-H08H
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