|Catalog||Size (Price)||Quantity||In Stock||Operation||Other Information|
Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide Protein Datasheet
FCER1A / FcERI Protein Price Inquiry ( Available Sizes )
FCER1A / FcERI Protein Product Information
|Synonym :||FCER1A, FCE1A|
A DNA sequence encoding the human FCER1A (P12319) (Met1-Gln205) was expressed with a polyhistidine tag at the C-terminus.
|Expression Host:||Human Cells|
FCER1A / FcERI Protein QC Testing
|Purity:||> 95% as determined by SDS-PAGE||SDS-PAGE:
FCER1A / FcERI protein
|Endotoxin:||< 1.0 EU per μg of the protein as determined by the LAL method|
|Stability:||Samples are stable for up to twelve months from date of receipt at -70℃|
|Predicted N terminal:||Val 26|
The recombinant human FCER1A consists of 191 amino acids and predicts a molecular mass of 24.5 KDa. It migrates as an approximately 42-48 KDa band in SDS-PAGE under reducing conditions.
|Formulation:||Lyophilized from sterile PBS, pH 7.4.
FCER1A / FcERI Protein Usage Guide
|Storage:||Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.|
|Reconstitution:||A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.|
FCER1A / FcERI Protein Related Products & Topics
|Molecule||Species||Description //For Detailed Info. and Price------CLICK!||Cat No|
|FcERI / FCER1A||Human||FCER1A / FcERI Protein, Recombinant||13193-H08H|
|FcERI / FCER1A||Mouse||FcERI / FCER1A Protein, Recombinant||50935-M02H|
FCER1A / FcERI Protein Description
FcERI, also known as FCER1A, is the alpha subunit of the immunoglobulin epsilon receptor (IgE receptor). IgE receptor is comprised of an alpha subunit(FcERI), a beta subunit, and two gamma subunits. IgE receptor is the initiator of the allergic response. When two or more high-affinity IgE receptors are brought together by allergen-bound IgE molecules, mediators such as histamine that are responsible for allergy symptoms are released. FcERI is glycosylated. It contains 2 Ig-like (immunoglobulin-like) domains.
- Shikanai T. et al., 2002, J Appl Physiol. 93 (1): 37-41.
- Sada K. et al., 2002, Blood. 100 (6): 2138-44.
- Takahashi K. et al., 2003, Mol Immunol. 38 (16-18): 1193-9.