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FABP4 / ALBP / A-FABP Antibody, Rabbit PAb, Antigen Affinity Purified

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Mouse FABP4 Antibody Product Information
Immunogen:Recombinant Mouse FABP4 protein (Catalog#50652-M08H)
Clone ID:
Ig Type:Rabbit IgG
Concentration:
Formulation:0.2 μm filtered solution in PBS with 5% trehalose
Preparation:Produced in rabbits immunized with purified, recombinant Mouse FABP4 (rM FABP4; Catalog#50652-M08H; NP_077717.1; Met 1-Ala 132). FABP4 specific IgG was purified by mouse FABP4 affinity chromatography .
Mouse FABP4 Antibody Usage Guide
Specificity:Mouse FABP4 / ALBP
Application:ELISA

ELISA: 0.1-0.2 μg/mL

This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Mouse FABP4. The detection limit for Mouse FABP4 is approximately 0.0195 ng/well.

Storage:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Other FABP4 Antibody Products
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    12109-R009-50
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      12109-RP01-400
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      12109-RP02-200
      12109-RP02-50
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      Application: IHC-P  
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      12109-R001-100
      12109-R001-50
      100 µg 
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      Reactivity: Mouse  
      Application: ELISA  
        50652-RP01-100
        50652-RP01-200
        50652-RP01-400
        100 µg 
        200 µg 
         
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        FABP4 /A-FABP Background

        Mouse fatty acid-binding protein, adipocyte, also known as Adipocyte-type fatty acid-binding protein, Fatty acid-binding protein 4, Adipocyte lipid-binding protein, and FABP4, is a cytoplasm protein which belongs to the calycin superfamily and Fatty-acid binding protein (FABP) family. In familial combined hyperlipidemia (FCHL), FABP4 correlated to body mass index (BMI), waist circumference and homeostasis model assessment (HOMA) index.FABP4 levels were associated with triglyceride-rich lipoproteins. In humans serum FABP4 levels correlate significantly with features of PCOS. It appears to be a determinant of atherogenic dyslipidemia. FABP4 pathway mediates the sebaceous gland hyperplasia in keratinocyte-specific Pten-null mice. FABP4 concentration significantly increased with an increasing of MS features and was strongly correlated with body-mass index, triglycerides, HDL-cholesterol concentrations and blood pressure. Patients in the highest quartile of FABP4 presented a six-fold increased odds ratio for MS and a three-fold increased odds for LD, adjusted by age, sex, body-mass index and the antiretroviral therapy. FABP4 is a strong plasma marker of metabolic disturbances in HIV-infected patients, and therefore, could serve to guide therapeutic intervention in this group of patients.

        Mouse FABP4 /A-FABP References
      • van Dongen,M.J. et al., 2002, J Am Chem Soc. 124 (40): 11874-80.
      • Coll, B. et al., 2008, Atherosclerosis  199 (1):147-53.
      • Hoashi,S. et al., 2008, BMC Genet. 9 :84.
      • Cai,H. et al., 2010, Bioorg Med Chem Lett  20 (12):3675-9.
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        Size / Price
        Catalog: 50652-RP02-50
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        All information of our products is subject to change without notice. Please refer to COA enclosed in shipped package for the newest information.
        Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"