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FABP4 /A-FABP Rabbit PAb

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    Mouse FABP4 Antibody Product Information
    Immunogen:Recombinant Mouse FABP4 protein (Catalog#50652-M08H)
    Clone ID:
    Ig Type:Rabbit IgG
    Concentration:
    Formulation:0.2 μm filtered solution in PBS with 5% trehalose
    Preparation:Produced in rabbits immunized with purified, recombinant Mouse FABP4 (rM FABP4; Catalog#50652-M08H; NP_077717.1; Met 1-Ala 132). Total IgG was purified by Protein A affinity chromatography .
    Other FABP4 Antibody Products
    Reactivity: Human  
    Application: ELISA  
      12109-R009-50
      12109-R009-100
      50 µg 
      100 µg 
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      Reactivity: Human  
      Application: ELISA  
        12109-RP01-400
        12109-RP01-100
        12109-RP01-200
         
        100 µg 
        200 µg 
        Add to Cart
        Reactivity: Human  
        Application: ELISA  WB  IP  
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        12109-RP02-200
        12109-RP02-50
        12109-RP02-100
        200 µg 
        50 µg 
        100 µg 
        Add to Cart
        Reactivity: Human  
        Application: IHC-P  
        • Slide 1
        • Slide 1
        12109-R001-100
        12109-R001-50
        100 µg 
        50 µg 
        Add to Cart
        Reactivity: Mouse  
        Application: ELISA  
          50652-RP02-50
          50652-RP02-100
          50652-RP02-200
          50 µg 
          100 µg 
          200 µg 
          Add to Cart
          FABP4 /A-FABP Background

          Fatty acid-binding protein, adipocyte, also known as Adipocyte-type fatty acid-binding protein, Fatty acid-binding protein 4, Adipocyte lipid-binding protein, and FABP4, is a cytoplasm protein which belongs to the calycin superfamily and Fatty-acid binding protein (FABP) family. In familial combined hyperlipidemia (FCHL), FABP4 correlated to body mass index (BMI), waist circumference and homeostasis model assessment (HOMA) index.FABP4 levels were associated with triglyceride-rich lipoproteins. In humans serum FABP4 levels correlate significantly with features of PCOS. It appears to be a determinant of atherogenic dyslipidemia. FABP4 pathway mediates the sebaceous gland hyperplasia in keratinocyte-specific Pten-null mice. FABP4 concentration significantly increased with an increasing of MS features and was strongly correlated with body-mass index, triglycerides, HDL-cholesterol concentrations and blood pressure. Patients in the highest quartile of FABP4 presented a six-fold increased odds ratio for MS and a three-fold increased odds for LD, adjusted by age, sex, body-mass index and the antiretroviral therapy. FABP4 is a strong plasma marker of metabolic disturbances in HIV-infected patients, and therefore, could serve to guide therapeutic intervention in this group of patients.

          Mouse FABP4 /A-FABP References
        • van Dongen,M.J. et al., 2002, J Am Chem Soc. 124 (40): 11874-80.
        • Coll, B. et al., 2008, Atherosclerosis  199 (1):147-53.
        • Hoashi,S. et al., 2008, BMC Genet. 9 :84.
        • Cai,H. et al., 2010, Bioorg Med Chem Lett  20 (12):3675-9.
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          All information of our products is subject to change without notice. Please refer to COA enclosed in shipped package for the newest information.
          Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"