Gene Summary: The intracellular fatty acid-binding proteins (FABPs) belongs to a multigene family. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Fatty acid-binding protein 3 gene contains four exons and its function is to arrest growth of mammary epithelial cells. This FABP3 gene is a candidate tumor suppressor gene for human breast cancer. [provided by RefSeq, Jul 2008]General information above from NCBI
Domain: Forms a beta-barrel structure that accommodates the hydrophobic ligand in its interior.
Subcellular location: Cytoplasm.
Sequence similarity: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.C