Ephrin B3 / EFNB3 Protein

Protein Ephrin B3

Ephrin B3 / EFNB3 Products

Ephrin B3 / EFNB3 Protein, Recombinant

Molecule	Species	Description //For Detailed Info. and Price------CLICK!	Cat No
Ephrin B3 / EFNB3	Rat	EFNB3 / Ephrin B3 Protein, Recombinant	80112-R02H
Ephrin B3 / EFNB3	Rat	EFNB3 /Ephrin B3 Protein, Recombinant	80112-R08H

Ephrin B3 / EFNB3 Related Areas

Neuroscience>>Axon Guidance>>Ephrin & Eph Receptor>>Ephrin B3 / EFNB3

Cancer>>Growth Factor & Receptor>>Ephrin & Eph Receptor>>Ephrin B3 / EFNB3

Ephrin B3 / EFNB3 Alternative Names

EFL6, EPLG8, LERK8, EPH-related receptor transmembrane ligand ELK-L3,Ephrin B3 / EFNB3, eph-related receptor tyrosine kinase ligand 8 [Homo sapiens]

RP23-56I20.5, EFL-6, ELF-3, Elk-L3, Epl8, LERK-8, NLERK-2, ephrin-B3 [Mus musculus]

Ephrin B3 / EFNB3 Background

Ephrin B3 belongs to the ephrin family. Ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. Ephrin B3 is important in brain development as well as in its maintenance. It is especially important for forebrain function since its expression levels were particularly high in several forebrain subregions compared to other brain subregions. Ephrin B3 binds to, and induce the collapse of, commissural axons/growth cones in vitro. It may play a role in constraining the orientation of longitudinally projecting axons.

Ephrin B3 / EFNB3 Related Studies

1. Takemoto M, et al. (2002) Ephrin-B3-EphA4 interactions regulate the growth of specific thalamocortical axon populations in vitro. Eur J Neurosci. 16(6):1168-72.
2. Brückner K, et al. (1999) EphrinB ligands recruit GRIP family PDZ adaptor proteins into raft membrane microdomains. Neuron. 22(3):511-24.
3. Bergemann A, et al. (1998) Ephrin-B3, a ligand for the receptor EphB3, expressed at the midline of the developing neural tube. Oncogene. 16(4):471-80.