Ephrin-B1 / EFNB1 Protein & Antibody

Ephrin-B1 / EFNB1 Products

Ephrin-B1 / EFNB1 Protein, Recombinant

Molecule	Species	Description //For Detailed Info. and Price------CLICK!	Cat. No
Ephrin-B1/EFNB1	Human	Ephrin-B1/EFNB1 Protein, Recombinant	10894-H03H
Ephrin-B1/EFNB1	Human	Ephrin-B1/EFNB1 Protein, Recombinant	10894-H08H
Ephrin-B1/EFNB1	Mouse	Ephrin-B1/EFNB1/Fc Protein, Recombinant	50580-M02H
Ephrin-B1/EFNB1	Mouse	Ephrin-B1/EFNB1 Protein, Recombinant	50580-M08H
Ephrin-B1/EFNB1	Rat	EFNB1 / Ephrin-B1 Protein, Recombinant	80106-R02H
Ephrin-B1/EFNB1	Rat	Rat EFNB1 / Ephrin-B1 Protein, Recombinant	80106-R08H

  10894-H03H: Immobilized mouse EphB3 at 2 µg/ml (100 µl/well) can bind human EFNB1 Fc chimera with a linear ranger of 1.56-25 ng/ml. Measured by its binding ability in a functional ELISA.

  50580-M02H: Immobilized mouse EphB3 at 2 µg/ml (100 µl/well) can bind mouse EFNB1 with a linear range of 0.1-12.5 ng/ml. Measured by its binding ability in a functional ELISA.

  50580-M08H:  Measured by its ability to compete with mouse EphrinB1/Fc for binding to immobilized mouse EphB3 in a functional ELISA assay.

Ephrin-B1 / EFNB1 Antibody

Molecule	Application	Description //For Detailed Info. and Price------CLICK!	Cat. No
Human Ephrin-B1/EFNB1	WB, ELISA	Ephrin-B1/EFNB1 Antibody, Rabbit PAb	10894-RP01
Human Ephrin-B1/EFNB1	WB, ELISA	Ephrin-B1/EFNB1 Antibody, Rabbit PAb (Antigen Affinity Purified)	10894-RP02
Mouse Ephrin-B1/EFNB1	WB, ELISA	Ephrin-B1 / EFNB1 Antibody (Antigen Affinity Purified)	50580-RP02

Ephrin-B1 / EFNB1 cDNA Clone

Molecule	Species	Description //For Detailed Info. and Price------CLICK!	Cat. No
Ephrin-B1/EFNB1	Human	Homo sapiens Ephrin-B1/EFNB1 cDNA Clone(NM_004429.4)	HG10894-M
Ephrin-B1/EFNB1	Mouse	Mus musculus Ephrin-B1/EFNB1 cDNA Clone	MG50580-M
Ephrin-B1/EFNB1	Rat	EFNB1 cDNA Clone / ORF Clone	RG80106-G

Ephrin-B1 / EFNB1 Alternative Names

Ephrin-B1, EFNB1, EFL3, EPLG2, Elk-L, LERK2, RP3-496G1.1, CFND, CFNS, MGC8782 [Homo sapiens]

Ephrin B1, Efnb1, EFL-3, Eplg2, Elk-L, LERK-2, Lerk2, RP23-110A15.1, Cek5-L, Epl2, Stra1 [Mus musculus]

Ephrin-B1 / EFNB1 Related Areas

Neuroscience>>Axon Guidance>>Ephrin & Eph Receptor>>Ephrin-B1/EFNB1

Cancer>>Growth Factor & Receptor>>Ephrin & Eph Receptor>>Ephrin-B1/EFNB1

Ephrin-B1 / EFNB1 Related Products

Protein Products

Molecule	Species	Description
EphA4	Human	EphA4 Protein, Recombinant
EphA4	Mouse	EphA4/Fc Protein, Recombinant
EphA4	Mouse	EphA4 Protein, Recombinant
EphA6/EHK-2	Mouse	EphA6 /EHK2 Protein, Recombinant
EphA6/EHK-2	Mouse	EphA6 /EHK2 Protein, Recombinant
EphA7	Human	EphA7 Protein, Recombinant
EphA7	Mouse	EphA7 Protein, Recombinant
EphB2	Human	EphB2/Fc Protein, Recombinant
EphB2	Human	EphB2 Protein, Recombinant
EphB4	Human	EphB4/Fc Protein, Recombinant
EphB4	Human	EphB4 Protein, Recombinant
EphB4	Human	EphB4 Protein, Recombinant
EphB4	Mouse	EphB4/Fc Protein, Recombinant
EphB4	Mouse	EphB4 Protein, Recombinant
EphB6	Human	EphB6/Fc Protein, Recombinant
EphB6	Human	EphB6 Protein, Recombinant
EphB6	Human	EphB6 Protein, Recombinant
Ephrin-A1/EFNA1	Human	Ephrin-A1/EFNA1/Fc Protein, Recombinant
Ephrin-A1/EFNA1	Human	Ephrin-A1/EFNA1 Protein, Recombinant
Ephrin-A1/EFNA1	Mouse	Ephrin-A1/EFNA1/Fc Protein, Recombinant
Ephrin-A1/EFNA1	Mouse	Ephrin-A1/EFNA1 Protein, Recombinant
Ephrin-A3/EFNA3	Human	Ephrin-A3/EFNA3/Fc Protein, Recombinant
Ephrin-A3/EFNA3	Human	Ephrin-A3/EFNA3/Fc Protein, Recombinant
Ephrin-A3/EFNA3	Human	Ephrin-A3/EFNA3 Protein, Recombinant
Ephrin-A3/EFNA3	Human	Ephrin-A3/EFNA3 Protein, Recombinant
Ephrin-A3/EFNA3	Mouse	Ephrin-A3/EFNA3 Protein, Recombinant
Ephrin-A5/EFNA5	Human	Ephrin-A5/EFNA5/Fc Protein, Recombinant
Ephrin-A5/EFNA5	Human	Ephrin-A5/EFNA5 Protein, Recombinant
Ephrin-A5/EFNA5	Mouse	Ephrin-A5/EFNA5/Fc Protein, Recombinant
Ephrin-A5/EFNA5	Mouse	Ephrin-A5/EFNA5 Protein, Recombinant
Ephrin-B2/EFNB2	Human	EphrinB2/EFNB2 Protein, Recombinant
Ephrin-B2/EFNB2	Human	EphrinB2/EFNB2 Protein, Recombinant
Ephrin-B2/EFNB2	Mouse	EphrinB2/EFNB2/Fc Protein, Recombinant
Ephrin-B2/EFNB2	Mouse	EphrinB2/EFNB2 Protein, Recombinant

Antibody Products

Molecule	Application	Description
Human EphB2	WB, ELISA	Rabbit Polyclonal Antibody (Antigen Affinity Purified)
Human EphB4	WB	Mouse Monoclonal Antibody
Human EphB4	ELISA	Mouse Monoclonal Antibody
Human EphB4	WB, ELISA	Rabbit Monoclonal Antibody
Human EphB4	ELISA	Rabbit Polyclonal Antibody
Human EphB4	WB, ELISA	Rabbit Polyclonal Antibody (Antigen Affinity Purified)
Human Ephrin-A1/EFNA1	WB, ELISA	Mouse Monoclonal Antibody
Human Ephrin-A1/EFNA1	WB, ELISA	Rabbit Polyclonal Antibody
Human Ephrin-A1/EFNA1	WB, ELISA	Rabbit Polyclonal Antibody (Antigen Affinity Purified)
Human Ephrin-A5/EFNA5	WB, ELISA	Rabbit Polyclonal Antibody
Human Ephrin-A5/EFNA5	WB, ELISA	Rabbit Polyclonal Antibody (Antigen Affinity Purified)

cDNA Clone Products

Molecule	Species	Description
EphA3	Human	Homo sapiens EphA3 cDNA Clone
EphA4	Human	Homo sapiens EphA4 cDNA Clone
EphA4	Mouse	Mus musculus EphA4 cDNA Clone
EphA6/EHK-2	Mouse	Mus musculus EphA6/EHK2 cDNA Clone
EphA7	Human	Homo sapiens EphA7 cDNA Clone
EphA7	Mouse	Mus musculus EphA7 cDNA Clone
EphB2	Human	Homo sapiens EphB2 cDNA Clone
EphB4	Human	Homo sapiens EphB4 cDNA Clone(NM_004444.4)
EphB4	Mouse	Mus musculus EphB4 cDNA Clone
EphB6	Human	Homo sapiens EphB6 cDNA Clone(NM_004445.2)
Ephrin-A1/EFNA1	Human	Homo sapiens Ephrin-A1/EFNA1 cDNA Clone(NM_004-428.2)
Ephrin-A3/EFNA3	Human	Homo sapiens Ephrin-A3/EFNA3 cDNA Clone(NM_004952.4)
Ephrin-A4/EFNA4	Human	Homo sapiens Ephrin-A4/EFNA4 cDNA Clone
Ephrin-A5/EFNA5	Human	Homo sapiens Ephrin-A5/EFNA5 cDNA Clone(NM_001962.1)
Ephrin-A5/EFNA5	Mouse	Mus musculus Ephrin-A5/EFNA5 cDNA Clone
Ephrin-B2/EFNB2	Human	Homo sapiens Ephrin-B2/EFNB2 cDNA Clone(NM_004093.2)
Ephrin-B2/EFNB2	Mouse	Mus musculus EphrinB2/EFNB2 cDNA Clone

Ephrin-B1 / EFNB1 Background

Ephrin-B1 also known as EFNB1, is a member of the ephrin family. The transmembrane- associated ephrin ligands and their Eph family of receptor tyrosine kinases are expressed by cells of the SVZ. Eph/ephrin interactions are implicated in axon guidance, neural crest cell migration, establishment of segmental boundaries, and formation of angiogenic capillary plexi. Eph receptors and ephrins are divided into two subclasses, A and B, based on binding specificities. Ephrin subclasses are further distinguished by their mode of attachment to the plasma membrane: ephrin-A ligands bind EphA receptors and are anchored to the plasma membrane via a glycosylphosphatidylinositol (GPI) linkage, whereas ephrin-B ligands bind EphB receptors and are anchored via a transmembrane domain. An exception is the EphA4 receptor, which binds both subclasses of ephrins. EphrinB1 and B class Eph receptors provide positional cues required for the normal morphogenesis of skeletal elements. Another malformation, preaxial polydactyly, was exclusively seen in heterozygous females in which expression of the X-linked ephrinB1 gene was mosaic, so that ectopic EphB-ephrinB1 interactions led to restricted cell movements and the bifurcation of digital rays.

Ephrin-B1 / EFNB1 Related Studies

1. Davy A, et al. (2004) Ephrin-B1 forward and reverse signaling are required during mouse development. Genes Dev. 18(5): 572-83.
2. Compagni A, et al. (2003) Control of skeletal patterning by ephrinB1-EphB interactions. Dev Cell. 5(2): 217-30.
3. Wieland I, et al. (2004) Mutations of the ephrin-B1 gene cause craniofrontonasal syndrome. Am J Hum Genet. 74(6): 1209-15.