Anti-Ephrin-B1 Antibody

Cat: 10894-RP01
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Anti-Ephrin-B1 Antibody (Rabbit Polyclonal antibody) General Information
Product name
Anti-Ephrin-B1 Antibody
Validated applications
Species reactivity
Reacts with: Human
Human Ephrin-B1
Recombinant Human EFNB1 protein (Catalog#10894-H08H)
Produced in rabbits immunized with purified, recombinant Human EFNB1 (rh EFNB1; Catalog#10894-H08H; NP_004420.1; Met 1-Gly 232). Total IgG was purified by Protein A affinity chromatography .
Polyclonal Rabbit IgG
Protein A
0.2 μm filtered solution in PBS with 5% trehalose
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-Ephrin-B1 Antibody (Rabbit Polyclonal antibody) Validated Applications
Application Dilution Notes
ELISA 1:1000-1:2000  

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-Ephrin-B1 Antibody Alternative Names
Anti-CFND Antibody;Anti-CFNS Antibody;Anti-EFB1 Antibody;Anti-EFL3 Antibody;Anti-Elk-L Antibody;Anti-EPLG2 Antibody;Anti-LERK2 Antibody
Ephrin-B1 Background Information

Ephrin-B1 also known as EFNB1, is a member of the ephrin family. The transmembrane- associated ephrin ligands and their Eph family of receptor tyrosine kinases are expressed by cells of the SVZ. Eph/ephrin interactions are implicated in axon guidance, neural crest cell migration, establishment of segmental boundaries, and formation of angiogenic capillary plexi. Eph receptors and ephrins are divided into two subclasses, A and B, based on binding specificities. Ephrin subclasses are further distinguished by their mode of attachment to the plasma membrane: ephrin-A ligands bind EphA receptors and are anchored to the plasma membrane via a glycosylphosphatidylinositol (GPI) linkage, whereas ephrin-B ligands bind EphB receptors and are anchored via a transmembrane domain. An exception is the EphA4 receptor, which binds both subclasses of ephrins. EphrinB1 and B class Eph receptors provide positional cues required for the normal morphogenesis of skeletal elements. Another malformation, preaxial polydactyly, was exclusively seen in heterozygous females in which expression of the X-linked ephrinB1 gene was mosaic, so that ectopic EphB-ephrinB1 interactions led to restricted cell movements and the bifurcation of digital rays.

Full Name
  • Davy A, et al. (2004) Ephrin-B1 forward and reverse signaling are required during mouse development. Genes Dev. 18(5): 572-83.
  • Compagni A, et al. (2003) Control of skeletal patterning by ephrinB1-EphB interactions. Dev Cell. 5(2): 217-30.
  • Wieland I, et al. (2004) Mutations of the ephrin-B1 gene cause craniofrontonasal syndrome. Am J Hum Genet. 74(6): 1209-15.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-Ephrin-B1 Antibody Rabbit Polyclonal ELISA 80106-RP01
    Anti-Ephrin-B1 Antibody Rabbit Polyclonal WB,ELISA,IP 80106-T52
    Anti-Ephrin-B1 Antibody Rabbit Polyclonal ELISA 50580-RP02
    Anti-Ephrin-B1 Antibody Rabbit Polyclonal ELISA 10894-RP02
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