Anti-Ephrin A2 Antibody

Cat: 50579-RP01
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Anti-Ephrin A2 Antibody (Rabbit Polyclonal antibody) General Information
Product name
Anti-Ephrin A2 Antibody
Validated applications
ELISA
Species reactivity
Reacts with: Mouse
Specificity
Mouse Ephrin A2
Immunogen
Recombinant Mouse Ephrin-A2 / EFNA2 protein (Catalog#50579-M08H)
Preparation
Produced in rabbits immunized with purified, recombinant Mouse Ephrin-A2 / EFNA2 (rM Ephrin-A2 / EFNA2; Catalog#50579-M08H; NP_031935.3; Met 1-Asn 184). Total IgG was purified by Protein A affinity chromatography.
Source
Polyclonal Rabbit IgG
Purification
Protein A
Formulation
0.2 μm filtered solution in PBS with 5% trehalose
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-Ephrin A2 Antibody (Rabbit Polyclonal antibody) Validated Applications
Application Dilution Notes
ELISA 1:1000-1:2000  

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-Ephrin A2 Antibody Alternative Names
Anti-CEK7L Antibody;Anti-Elf1 Antibody;Anti-Epl6 Antibody;Anti-Eplg6 Antibody;Anti-Lerk6 Antibody
Ephrin A2 Background Information

Ephrin-A2 also known as EFNA2 or EPH-related receptor tyrosine kinase ligand 6, is a member of the ephrin family. The Eph family receptor interacting proteins (ephrins) are a family of proteins that serve as the ligands of the Eph receptor, which compose the largest known subfamily of receptor protein-tyrosine kinases (RTKs). Ephrin-A2 and their Eph family of receptor tyrosine kinases are expressed by cells of the SVZ. Eph/ephrin interactions are implicated in axon guidance, neural crest cell migration, establishment of segmental boundaries, and formation of angiogenic capillary plexi. Ephrin subclasses are further distinguished by their mode of attachment to the plasma membrane: ephrin-A ligands bind EphA receptors and are anchored to the plasma membrane via a glycosylphosphatidylinositol (GPI) linkage, whereas ephrin-B ligands bind EphB receptors and are anchored via a transmembrane domain. Ephrin-A2 regulates the position-specific affinity of limb mesenchyme and is involved in cartilage pattern formation in the limb.

Full Name
ephrin-A2
References
  • Feldheim DA, et al. (2000) Genetic analysis of ephrin-A2 and ephrin-A5 shows their requirement in multiple aspects of retinocollicular mapping. Neuron. 25(3): 563-74.
  • Jurney WM, et al. (2002) Rac1-mediated endocytosis during ephrin-A2- and semaphorin 3A-induced growth cone collapse. J Neurosci. 22(14): 6019-28.
  • Holmberg J, et al. (2005) Ephrin-A2 reverse signaling negatively regulates neural progenitor proliferation and neurogenesis. Genes Dev. 19(4): 462-71.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-Ephrin A2 Antibody Rabbit Polyclonal ELISA 50579-RP02
    Anti-Ephrin A2 Antibody Rabbit Polyclonal ELISA 50579-T16
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