Anti-Ephrin-A1 Antibody

Cat: 10882-R114

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Anti-Ephrin-A1 Antibody (Rabbit Monoclonal antibody) General Information
Product name
Anti-Ephrin-A1 Antibody
Validated applications
Species reactivity
Reacts with: Human
Human Ephrin-A1
No cross-reactivity in ELISA with Human EphrinA5 / EFNA5 Human EphrinA3 / EFNA3
Recombinant Human EFNA1 protein (Catalog#10882-H08H)
This antibody was obtained from a rabbit immunized with purified, recombinant Human EphrinA1 (rh EphrinA1; Catalog#10882-H08H; NP_004419.2; Met 1-Ser 182).
Monoclonal Rabbit IgG Clone #114
Protein A
0.2 μm filtered solution in PBS with 5% trehalose
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-Ephrin-A1 Antibody (Rabbit Monoclonal antibody) Validated Applications
Application Dilution Notes
ELISA 1:5000-1:10000  
ELISA(Det) 1:1000-1:10000 This antibody will detect Human Ephrin-A1 / EFNA1 in ELISA pair set (Catalog: # SEK10882). In a sandwich ELISA, it can be used as detection antibody when paired with (Catalog: # 10882-MM01).

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-Ephrin-A1 Antibody Alternative Names
Anti-B61 Antibody;Anti-ECKLG Antibody;Anti-EFL1 Antibody;Anti-EFNA1 Antibody;Anti-EPLG1 Antibody;Anti-LERK-1 Antibody;Anti-LERK1 Antibody;Anti-TNFAIP4 Antibody
Ephrin-A1 Background Information

EPH-related receptor tyrosine kinase ligand 1 (abbreviated as Ephrin-A1) also known as ligand of eph-related kinase 1 or EFNA1, is a member of the ephrin (EPH) family. The Eph family receptor interacting proteins (ephrins) are a family of proteins that serve as the ligands of the Eph receptor, which compose the largest known subfamily of receptor protein-tyrosine kinases (RTKs). Ephrin-A1/EFNA1 and its Eph family of receptor tyrosine kinases are expressed by cells of the SVZ. Ephrin subclasses are further distinguished by their mode of attachment to the plasma membrane: ephrin-A ligands bind EphA receptors and are anchored to the plasma membrane via a glycosylphosphatidylinositol (GPI) linkage, whereas ephrin-B ligands bind EphB receptors and are anchored via a transmembrane domain. An exception is the EphA4 receptor, which binds both subclasses of ephrins. Ephrin-A1 and one of its receptor EphA2 were expressed in xenograft endothelial cells and also tumor cells and play a role in human cancers, at least in part by influencing tumor neovascularization.

Full Name
  • Deroanne C, et al. (2003) EphrinA1 inactivates integrin-mediated vascular smooth muscle cell spreading via the Rac/PAK pathway. J Cell Sci. 116(7): 1367-76.
  • Ojima T, et al. (2006) EphrinA1 inhibits vascular endothelial growth factor-induced intracellular signaling and suppresses retinal neovascularization and blood-retinal barrier breakdown. Am J Pathol. 168(1): 331-9.
  • Wu D, et al. (2004) Prognostic value of EphA2 and EphrinA-1 in squamous cell cervical carcinoma. Gynecol Oncol. 94(2): 312-9.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-Ephrin-A1 Antibody Rabbit Polyclonal ELISA 80115-RP01
    Anti-Ephrin-A1 Antibody Rabbit Polyclonal ELISA 50593-RP01
    Anti-Ephrin-A1 Antibody Rabbit Polyclonal ELISA 50593-RP02
    Anti-Ephrin-A1 Antibody Mouse Monoclonal ELISA,ELISA(Cap) 10882-MM01
    Anti-Ephrin-A1 Antibody Rabbit Polyclonal ELISA,IHC-P 10882-RP02
    Anti-Ephrin-A1 Antibody Rabbit Polyclonal ELISA 10882-RP01
    Anti-Ephrin-A1 Antibody Rabbit Monoclonal IHC-P 10882-R453
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