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EphB3 / HEK2 Antibody, Rabbit MAb
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EphB3 / HEK2 Antibody, Rabbit MAb PDF Download

Catalog   Size (Price) Quantity In Stock Operation
50581-R115  

YES   
 

Primary antibody | Secondary antibody | Tag antibody | Isotype control antibody | Loading control antibody | Antibody Purification

EphB3 / HEK2 Antibody Datasheet

  Order or Inquire for EphB3 / HEK2 Antibody product Quality antibodies Antibody production services
  Detection limit is 0. 15625 ng/well in ELISA
 

EphB3 / HEK2 Antibody Product Information

Immunogen :

Recombinant Mouse EphB3 / HEK2 protein (Catalog#50581-M08H)

Antibody Type : Rabbit Monoclonal Antibody ( Rabbit mAb Service Platform )

Clone ID :

115

Ig Type :

Rabbit IgG

Formulation : 0.2 μm filtered solution in PBS, 5% trehalose may be added in some batches. Please read the hardcopy of COA or contact our customer service to confirm the formulation.
Preparation :

This antibody was obtained from a rabbit immunized with purified, recombinant Mouse EphB3 / HEK2 (rM EphB3 / HEK2; Catalog#50581-M08H; NP_034273.1; Met 1-Thr 537).

EphB3 / HEK2 Antibody Usage Guide

Specificity :

Mouse EphB3 / HEK2

 

No cross-reactivity in ELISA with

Human LRPAP1

Direct ELISA : This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Mouse EphB3. The detection limit for Mouse EphB3 is approximately 0. 15625 ng/well.
Storage : This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

EphB3 / HEK2 Antibody Related Products & Topics

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Proteins:

Antibodies:

EphB3 / HEK2 Antibody Background

Ephrin type-B receptor 3, EPH-like kinase 2, Tyrosine-protein kinase TYRO6, EPHB3, ETK2, HEK2 and TYRO6, is a single-pass type I membrane protein which belongs to theprotein kinase superfamily, tyr protein kinase family, ephrin receptor subfamily. EPHB3 contains twofibronectin type-III domains, oneprotein kinase domain and oneSAM (sterile alpha motif) domain. EphB3 is initially expressed in the sclerotome, but later is expressed predominantly in the dermatome. It is prominent expression is also detected in the developing heart, liver, posterior ventral limb bud mesenchyme, pharyngeal arches, and head mesenchyme. The EphB3 receptors are expressed during embryonic development in multiple regions of the central nervous system. The spatial profile of EphB3 receptors is co-localized to regions of the brain that had a high level of EphB3 receptor binding ligands. Its expression pattern suggests that EphB3 may play a role in the maintenance of mature neuronal connections or re-arrangement of synaptic connections during late stages of development. EphB3-ephrin-B interaction promotes MET by re-establishing epithelial cell-cell junctions and such an MET-promoting effect contributes to EphB3-mediated tumor suppression.

References

  1. Baker,R.K. et al., 2001,Mech Dev. 104 (1-2): 129-32.
  2. Willson,C.A. et al., 2003, Cell Transplant. 12 (3): 279-90.
  3. Willson,C.A. et al., 2006, J Mol Histol. 37 (8-9): 369-80.
  4. Risley,M. et al., 2009, Mech Dev. 126 (3-4): 230-9.
  5. Chiu,S.T. et al., 2009, Carcinogenesis. 30 (9): 1475-86.
 
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"