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> EphA4 Protein & Antibody EphA4 Protein & Antibody
Eph receptor A4
EphA4 Products
EphA4 Protein, Recombinant
| Molecule | Species | Description //For Detailed Info. and Price------CLICK! | Cat. No |
| EphA4 | Human | EPHA4 / HEK8 / TYRO1 Protein, Recombinant  |
11314-H03H |
| EphA4 | Human | EPHA4 / HEK8 / TYRO1 Protein, Recombinant | 11314-H08H |
| EphA4 | Human | EPHA4 / HEK8 / TYRO1(aa 570-986) Protein, Recombinant, with GST Tag | 11314-H20B1 |
| EphA4 | Mouse | EPHA4 / HEK8 / TYRO1/Fc Protein, Recombinant |
50575-M02H |
| EphA4 | Mouse | EPHA4 / HEK8 / TYRO1 Protein, Recombinant |
50575-M08H |
| EphA4 | Rat | EPHA4 / HEK8 / TYRO1 Protein, Recombinant | 80123-R02H |
| EphA4 | Rat | EPHA4 / HEK8 / TYRO1 Protein, Recombinant | 80123-R08H |
| EphA4 | Cynomolgus | EPHA4 / HEK8 / TYRO1 Protein, Recombinant | 90039-C02H |
| EphA4 | Cynomolgus | EPHA4 Protein, Recombinant | 90039-C08H |
EphA4 Antibody
| Molecule | Application | Description //For Detailed Info. and Price------CLICK! | Cat. No |
| Human EphA4 |
WB, ELISA | EPHA4 / HEK8 / TYRO1 Antibody, Rabbit PAb | 11314-RP01 |
| Human EphA4 |
WB, ELISA | EPHA4 / HEK8 / TYRO1 Antibody, Rabbit PAb (Antigen Affinity Purified) | 11314-RP02 |
EphA4 cDNA Clone
| Molecule | Species | Description //For Detailed Info. and Price------CLICK! | Cat. No |
|
EphA4 |
Human |
HG11314-M | |
| EphA4 | Mouse | Mus musculus EPHA4 / HEK8 / TYRO1 cDNA Clone | MG50575-M |
| EphA4 | Rat | Rat EPHA4 / HEK8 / TYRO1 Gene cDNA Clone / ORF Clone | RG80123-G |
| EphA4 | Cynomolgus | Cynomolgus monkey EPHA4 / HEK8 / TYRO1 Gene cDNA Clone / ORF Clone | CG90039-G |
EphA4 Related Areas
Enzyme>>Protein Kinase>>Receptor Tyrosine Kinase>>EphA4
Signal Transduction>>Protein Kinase>>Receptor Tyrosine Kinase>>EphA4
Neuroscience>>Axon Guidance>>Ephrin & Eph Receptor>>EphA4
Cancer>>Growth Factor & Receptor>>Receptor Tyrosine Kinase>>EphA4
Cancer>>Growth Factor & Receptor>>Ephrin & Eph Receptor>>EphA4
EphA4 Alternative Names
EphA4, HEK8, SEK, TYRO1 [Homo sapiens]
Epha4, Hek8, Sek, Tyro1, Sek1, 2900005C20Rik, AI385584, Cek8, rb [Mus musculus]
EphA4 Related Products
Protein Products
Antibody Products
| Molecule | Application | Description //For Detailed Info. and Price------CLICK! |
| Human EphB2 |
WB, ELISA | Rabbit Polyclonal Antibody (Antigen Affinity Purified) |
| Human EphB4 |
WB | Mouse Monoclonal Antibody |
| Human EphB4 |
ELISA | Mouse Monoclonal Antibody |
| Human EphB4 |
WB, ELISA | Rabbit Monoclonal Antibody |
| Human EphB4 |
ELISA | Rabbit Polyclonal Antibody |
| Human EphB4 |
WB, ELISA | Rabbit Polyclonal Antibody (Antigen Affinity Purified) |
| Human Ephrin-A1/EFNA1 |
WB, ELISA | Mouse Monoclonal Antibody |
| Human Ephrin-A1/EFNA1 |
WB, ELISA | Rabbit Polyclonal Antibody |
| Human Ephrin-A1/EFNA1 |
WB, ELISA | Rabbit Polyclonal Antibody (Antigen Affinity Purified) |
| Human Ephrin-A5/EFNA5 |
WB, ELISA | Rabbit Polyclonal Antibody |
| Human Ephrin-A5/EFNA5 |
WB, ELISA | Rabbit Polyclonal Antibody (Antigen Affinity Purified) |
cDNA Clone Products
EphA4 Background
EPH receptor A4 (ephrin type-A receptor 4), also known as EphA4, belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family which 16 known receptors (14 found in mammals) are involved: EPHA1, EPHA2, EPHA3, EPHA4, EPHA5, EPHA6, EPHA7, EPHA8, EPHA9, EPHA10, EPHB1, EPHB2, EPHB3, EPHB4, EPHB5, EPHB6. The Eph family of receptor tyrosine kinases (comprising EphA and EphB receptors) has been implicated in synapse formation and the regulation of synaptic function and plasticity6. EphA4 is enriched on dendritic spines of pyramidal neurons in the adult mouse hippocampus, and ephrin-A3 is localized on astrocytic processes that envelop spines. Eph receptor−mediated signaling, which is triggered by ephrins7, probably modifies the properties of synapses during synaptic activation and remodeling. Ephrin receptors are components of cell signalling pathways involved in animal growth and development, forming the largest sub-family of receptor tyrosine kinases (RTKs). The extracellular domain of an EphA4 interacts with ephrin ligands, which may be tethered to neighbouring cells. Ligand-mediated activation of Ephs induce various important downstream effects and Eph receptors have been studied for their potential roles in the development of cancer.
EphA4 Related Studies
- Murai KK, et al. (2003) Control of hippocampal dendritic spine morphology through ephrin-A3/EphA4 signaling. Nat Neurosci. 6(2): 153-60.
- Kullander K, et al. (2003) Role of EphA4 and EphrinB3 in local neuronal circuits that control walking. Science. 299(5614): 1889-92.
- Smith A, et al. (1997) The EphA4 and EphB1 receptor tyrosine kinases and ephrin-B2 ligand regulate targeted migration of branchial neural crest cells. Curr Biol. 7(8): 561-70.
