Quick Order

EpCAM / TROP-1 / TACSTD1 Antibody, Rabbit PAb, Antigen Affinity Purified

DatasheetReviewsRelated ProductsProtocols
Human EpCAM Antibody Product Information
Immunogen:Recombinant Human EpCAM protein (Catalog#10694-H08H)
Clone ID:
Ig Type:Rabbit IgG
Concentration:
Endotoxin:
Formulation:0.2 μm filtered solution in PBS with 5% trehalose
Preparation:Produced in rabbits immunized with purified, recombinant Human EpCAM / TROP1 (rh EpCAM; Catalog#10694-H08H; NP_002345.1; Met 1-Lys 265). EpCAM specific IgG was purified by human EpCAM affinity chromatography.
Human EpCAM Antibody Usage Guide
Specificity:Human EpCAM / TROP1 / CD326
Application:WB, ELISA

WB: 10-20 μg/mL

ELISA: 0.5-1.0 μg/mL

This antibody can be used at 0.5-1.0 μg/mL with the appropriate secondary reagents to detect Human EpCAM. The detection limit for Human EpCAM is 0.00245 ng/well.

Storage:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Human EpCAM Antibody WB Application Image
Other EpCAM Antibody Products
Reactivity: Human  
Application: ELISA  
    10694-RP01-100
    10694-RP01-200
    10694-RP01-400
    100 µg 
    200 µg 
     
    Add to Cart
    Reactivity: Human  
    Application: ELISA  WB  IHC-P  FCM  IF  IP  ICC/IF  
    • Slide 1
    • Slide 1
    • Slide 1
    • Slide 1
    • Slide 1
    • Slide 1
    • Slide 1
    • Slide 1
    10694-R028-50
    10694-R028-100
    50 µg 
    100 µg 
    Add to Cart
    Reactivity: Human  
    Application: ELISA  
      10694-MM07-50
      10694-MM07-100
      10694-MM07-200
      50 µg 
      100 µg 
      200 µg 
      Add to Cart
      Reactivity: Human  
      Application: FCM  
      • Slide 1
      10694-MM06-F-50
      10694-MM06-F-100
      50 Tests 
      100 Tests 
      Add to Cart
      Reactivity: Human   
      Application: FCM  
      • Slide 1
      10694-MM06-P-50
      10694-MM06-P-100
      50 Tests 
      100 Tests 
      Add to Cart
      Reactivity: Human  
      Application: FCM  
      • Slide 1
      10694-R028-A-100
      10694-R028-A-50
      100 Tests 
      50 Tests 
      Add to Cart
      Reactivity: Human  
      Application: FCM  
      • Slide 1
      10694-MM06-200
      10694-MM06-100
      10694-MM06-50
      200 µg 
      100 µg 
      50 µg 
      Add to Cart
      Reactivity: Human  
      Application: FCM  
      • Slide 1
      10694-MM06-A-100
      10694-MM06-A-50
      100 Tests 
      50 Tests 
      Add to Cart
      Reactivity: Human  
      Application: WB  IP  
      • Slide 1
      • Slide 1
      10694-MM05-100
      10694-MM05-50
      10694-MM05-200
      100 µg 
      50 µg 
      200 µg 
      Add to Cart
      Reactivity: Human  
      Application: FCM  
      • Slide 1
      10694-R028-P-100
      10694-R028-P-50
      100 Tests 
      50 Tests 
      Add to Cart
      Reactivity: Human  
      Application: FCM  
      • Slide 1
      10694-R028-F-100
      10694-R028-F-50
      100 Tests 
      50 Tests 
      Add to Cart
      Reactivity: Mouse  
      Application: ELISA  
        50591-RP01-100
        50591-RP01-200
        50591-RP01-400
        100 µg 
        200 µg 
         
        Add to Cart
        Reactivity: Mouse  
        Application: ELISA  IHC-P  
        • Slide 1
        • Slide 1
        • Slide 1
        50591-RP02-50
        50591-RP02-100
        50591-RP02-200
        50 µg 
        100 µg 
        200 µg 
        Add to Cart
        Reactivity: Mouse  
        Application: ELISA  WB  IHC-P  
        • Slide 1
        • Slide 1
        • Slide 1
        50591-R002-50
        50591-R002-100
        50 µg 
        100 µg 
        Add to Cart
        Reactivity: Mouse  
        Application: IHC-P  
        • Slide 1
        • Slide 1
        50591-R065-100
        50591-R065-50
        100 µg 
        50 µg 
        Add to Cart
        Reactivity: Rat  
        Application: ELISA  IHC-P  
        • Slide 1
        80306-T24-100
        80306-T24-200
        80306-T24-50
        100 µg 
        200 µg 
        50 µg 
        Add to Cart
        Reactivity: Cynomolgus  
        Application: ELISA  WB  IHC-P  IP  
        • Slide 1
        • Slide 1
        • Slide 1
        • Slide 1
        90299-T60-200
        90299-T60-100
        90299-T60-50
        200 µg 
        100 µg 
        50 µg 
        Add to Cart
        Reactivity: Cynomolgus  
        Application: ELISA  
          90299-RP01-400
          90299-RP01-100
          90299-RP01-200
           
          100 µg 
          200 µg 
          Add to Cart
          EpCAM/TROP-1/TACSTD1 Background

          Epithelial Cell Adhesion Molecule (EpCAM), also known as GA733-2 antigen, is a type â… transmembrane glycoprotein composed of an extracellular domain with two EGF-Like repeats and a cystenin-rich region, a transmembrane domain and a cytoplasmic domain. It modulates cell adhesion and proliferation. Its overexpression has been detected in many epithelial tumours and has been associated with high stage, high grade and a worse survival in some tumour types. EpCAM has been shown to function as a calcium-independent homophilic cell adhesion molecule that does not exhibit any obvious relationship to the four known cell adhesion molecule superfamilies. However, recent insights have revealed that EpCAM participates in not only cell adhesion, but also in proliferation, migration and differentiation of cells. In addition, recent study revealed that EpCAM is the Wnt-beta-catenin signaling target gene and may be used to facilitate prognosis. It has oncogenic potential and is activated by release of its intracellular domain, which can signal into the cell nucleus by engagement of elements of the wnt pathway.

          Human EpCAM/TROP-1/TACSTD1 References
        • Brunner A, et al. (2008) EpCAM is predominantly expressed in high grade and advanced stage urothelial carcinoma of the bladder. J Clin Pathol. 61(3):307-10.
        • Trzpis M, et al. (2008) EpCAM in morphogenesis. Front Biosci. 13: 5050-5.
        • Munz M, et al. (2009) The emerging role of EpCAM in cancer and stem cell signaling. Cancer Res. 69(14): 5627-9.
        • Carpenter G, et al. (2009) EpCAM: another surface-to-nucleus missile. Cancer Cell. 15(3): 165-6.
        • Product nameProduct name
          All information of our products is subject to change without notice. Please refer to COA enclosed in shipped package for the newest information.
          Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"