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EpCAM/TROP-1/TACSTD1 Rabbit MAb

  • Human EpCAM/TROP-1/TACSTD1 Flow Cytometry (FC) 4868
  • Human METTL1 Immunoprecipitation(IP) 8089
  • EpCAM / TROP-1 / TACSTD1 Antibody, Rabbit MAb, Flow cytometric
  • EpCAM / TROP-1 / TACSTD1 Antibody, Rabbit MAb, Immunofluorescence
  • EpCAM / TROP-1 / TACSTD1 Antibody, Rabbit MAb, Immunohistochemistry
  • EpCAM / TROP-1 / TACSTD1 Antibody, Rabbit MAb, Immunohistochemistry
  • EpCAM / TROP-1 / TACSTD1 Antibody, Rabbit MAb, Immunohistochemistry
  • EpCAM / TROP-1 / TACSTD1 Antibody, Rabbit MAb, Western blot
  • Influenza A Nucleoprotein / NP Antibody, Mouse MAb, Flow cytometric
  • EpCAM / TROP-1 / TACSTD1 Antibody, Rabbit MAb, Immunoprecipitation
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Human EpCAM Antibody Product Information
Immunogen:Recombinant Human EpCAM protein (Catalog#10694-H08H)
Clone ID:28
Ig Type:Rabbit IgG
Concentration:
Endotoxin:
Formulation:0.2 μm filtered solution in PBS with 5% trehalose
Preparation:This antibody was obtained from a rabbit immunized with purified, recombinant Human EpCAM / TROP1 (rh EpCAM; Catalog#10694-H08H; NP_002345.1; Met 1-Lys 265).
Human EpCAM Antibody WB Application Image
Human EpCAM Antibody IHC Application Image
EpCAM / TROP-1 / TACSTD1 Antibody, Rabbit MAb, Immunohistochemistry
[Click to enlarge image]
Caption:
Immunochemical staining of human EpCAM in human bladder carcinoma with rabbit monoclonal antibody (2 µg/mL, formalin-fixed paraffin embedded sections). Positive staining was localized to membrane of transitional epithelium.
EpCAM / TROP-1 / TACSTD1 Antibody, Rabbit MAb, Immunohistochemistry
[Click to enlarge image]
Caption:
Immunochemical staining of human EpCAM in human colon carcinoma with rabbit monoclonal antibody (2 µg/mL, formalin-fixed paraffin embedded sections). Positive staining was localized to membrane of colonic gland epithelium.
EpCAM / TROP-1 / TACSTD1 Antibody, Rabbit MAb, Immunohistochemistry
[Click to enlarge image]
Caption:
Immunochemical staining of human EpCAM in human mammary gland with rabbit monoclonal antibody (2 µg/mL, formalin-fixed paraffin embedded sections). Positive staining was localized to membrane of alveolus epithelium.
Human EpCAM Antibody IF Application Image
EpCAM / TROP-1 / TACSTD1 Antibody, Rabbit MAb, Immunofluorescence
[Click to enlarge image]
Caption:
Immunofluorescence staining of Human EpCAM in SKBR3 cells. Cells were fixed with 4% PFA, blocked with 10% serum, and incubated with Rabbit anti-Human EpCAM monoclonal antibody (10 µg/ml) at 4℃ overnight. Then cells were stained with the Alexa Fluor® 488-conjugated Goat Anti-rabbit IgG secondary antibody (green) and counterstained with DAPI (blue). Positive staining was localized to plasma membrane.
Human EpCAM Antibody FC Application Image
Influenza A Nucleoprotein / NP Antibody, Mouse MAb, Flow cytometric
[Click to enlarge image]
Caption:
High Five cells were infected by Bac-NP (solid line histogram) or Bac-NA (dashed line histogram), the cells were collected at 48 hours postinfection, and the levels of NP were measured by flow cytometry. Cells were fixed and permeabilized according to the manufacturer’s manual (Cat. No. 554714, BD Pharmingen) and subsequently stained with Purified Mouse Anti-H1N1-NP (11675-MM03, 1 μg/test) antibody for 20 min on ice. Cells were washed twice and incubated with 1 μg of a FITC Goat Anti-Mouse Ig secondary antibody for 20 min on ice. Cells were washed twice and analyzed by flow cytometry.
Human EpCAM Antibody IP Application Image
Other EpCAM Antibody Products
Reactivity: Human  
Application: ELISA  
    10694-RP01-100
    10694-RP01-200
    10694-RP01-400
    100 µg 
    200 µg 
     
    Add to Cart
    Reactivity: Human  
    Application: ELISA  
      10694-MM07-50
      10694-MM07-100
      10694-MM07-200
      50 µg 
      100 µg 
      200 µg 
      Add to Cart
      Reactivity: Human  
      Application: ELISA  WB  
      • Slide 1
      10694-RP02-50
      10694-RP02-100
      10694-RP02-200
      50 µg 
      100 µg 
      200 µg 
      Add to Cart
      Reactivity: Human  
      Application: FCM  
      • Slide 1
      10694-MM06-F-50
      10694-MM06-F-100
      50 Tests 
      100 Tests 
      Add to Cart
      Reactivity: Human   
      Application: FCM  
      • Slide 1
      10694-MM06-P-50
      10694-MM06-P-100
      50 Tests 
      100 Tests 
      Add to Cart
      Reactivity: Human  
      Application: FCM  
      • Slide 1
      10694-R028-A-100
      10694-R028-A-50
      100 Tests 
      50 Tests 
      Add to Cart
      Reactivity: Human  
      Application: FCM  
      • Slide 1
      10694-MM06-200
      10694-MM06-100
      10694-MM06-50
      200 µg 
      100 µg 
      50 µg 
      Add to Cart
      Reactivity: Human  
      Application: FCM  
      • Slide 1
      10694-MM06-A-100
      10694-MM06-A-50
      100 Tests 
      50 Tests 
      Add to Cart
      Reactivity: Human  
      Application: WB  IP  
      • Slide 1
      • Slide 1
      10694-MM05-100
      10694-MM05-50
      10694-MM05-200
      100 µg 
      50 µg 
      200 µg 
      Add to Cart
      Reactivity: Human  
      Application: FCM  
      • Slide 1
      10694-R028-P-100
      10694-R028-P-50
      100 Tests 
      50 Tests 
      Add to Cart
      Reactivity: Human  
      Application: FCM  
      • Slide 1
      10694-R028-F-100
      10694-R028-F-50
      100 Tests 
      50 Tests 
      Add to Cart
      Reactivity: Mouse  
      Application: ELISA  
        50591-RP01-100
        50591-RP01-200
        50591-RP01-400
        100 µg 
        200 µg 
         
        Add to Cart
        Reactivity: Mouse  
        Application: ELISA  IHC-P  
        • Slide 1
        • Slide 1
        • Slide 1
        50591-RP02-50
        50591-RP02-100
        50591-RP02-200
        50 µg 
        100 µg 
        200 µg 
        Add to Cart
        Reactivity: Mouse  
        Application: ELISA  WB  IHC-P  
        • Slide 1
        • Slide 1
        • Slide 1
        50591-R002-50
        50591-R002-100
        50 µg 
        100 µg 
        Add to Cart
        Reactivity: Mouse  
        Application: IHC-P  
        • Slide 1
        • Slide 1
        50591-R065-100
        50591-R065-50
        100 µg 
        50 µg 
        Add to Cart
        Reactivity: Rat  
        Application: ELISA  IHC-P  
        • Slide 1
        80306-T24-100
        80306-T24-200
        80306-T24-50
        100 µg 
        200 µg 
        50 µg 
        Add to Cart
        Reactivity: Cynomolgus  
        Application: ELISA  WB  IHC-P  IP  
        • Slide 1
        • Slide 1
        • Slide 1
        • Slide 1
        90299-T60-200
        90299-T60-100
        90299-T60-50
        200 µg 
        100 µg 
        50 µg 
        Add to Cart
        Reactivity: Cynomolgus  
        Application: ELISA  
          90299-RP01-400
          90299-RP01-100
          90299-RP01-200
           
          100 µg 
          200 µg 
          Add to Cart
          EpCAM/TROP-1/TACSTD1 Background

          Epithelial Cell Adhesion Molecule (EpCAM), also known as GA733-2 antigen, is a type â… transmembrane glycoprotein composed of an extracellular domain with two EGF-Like repeats and a cystenin-rich region, a transmembrane domain and a cytoplasmic domain. It modulates cell adhesion and proliferation. Its overexpression has been detected in many epithelial tumours and has been associated with high stage, high grade and a worse survival in some tumour types. EpCAM has been shown to function as a calcium-independent homophilic cell adhesion molecule that does not exhibit any obvious relationship to the four known cell adhesion molecule superfamilies. However, recent insights have revealed that EpCAM participates in not only cell adhesion, but also in proliferation, migration and differentiation of cells. In addition, recent study revealed that EpCAM is the Wnt-beta-catenin signaling target gene and may be used to facilitate prognosis. It has oncogenic potential and is activated by release of its intracellular domain, which can signal into the cell nucleus by engagement of elements of the wnt pathway.

          Immune Checkpoint   Immunotherapy   Cancer Immunotherapy   Targeted Therapy

          Human EpCAM/TROP-1/TACSTD1 References
        • Brunner A, et al. (2008) EpCAM is predominantly expressed in high grade and advanced stage urothelial carcinoma of the bladder. J Clin Pathol. 61(3):307-10.
        • Trzpis M, et al. (2008) EpCAM in morphogenesis. Front Biosci. 13: 5050-5.
        • Munz M, et al. (2009) The emerging role of EpCAM in cancer and stem cell signaling. Cancer Res. 69(14): 5627-9.
        • Carpenter G, et al. (2009) EpCAM: another surface-to-nucleus missile. Cancer Cell. 15(3): 165-6.
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          Size / Price
          Catalog: 10694-R028-1
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          Datasheet & Documentation

          All information of our products is subject to change without notice. Please refer to COA enclosed in shipped package for the newest information.
          Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"