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Endoglin / CD105 Antibody (FITC), Rabbit MAb

  • Endoglin / CD105 Antibody (FITC), Rabbit MAb, Flow cytometric
  • Endoglin / CD105 Antibody (FITC), Rabbit MAb, Flow cytometric
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Human CD105/ENG Antibody Product Information
Immunogen:Recombinant Human CD105 protein (Catalog#10149-H08H)
Clone ID:103
Ig Type:Rabbit IgG
Concentration:10 μl/Test, 0.1 mg/ml
Endotoxin:
Formulation:Aqueous solution containing 0.5% BSA and 0.09% sodium azide
Preparation:This antibody was obtained from a rabbit immunized with purified, recombinant Human Endoglin / CD105 (rh CD105; Catalog#10149-H08H; Met 1-Gly 586; NP_001108225.1) and conjugated with FITC under optimum conditions, the unreacted FITC was removed .
Human CD105/ENG Antibody FC Application Image
Endoglin / CD105 Antibody (FITC), Rabbit MAb, Flow cytometric
[Click to enlarge image]
Caption:
Flow cytometric analysis of CD105 expression on human HeLa cells. HeLa cells were stained with FITC Rabbit anti-Human CD105 antibody (solid line fluorescence histogram) or a negative control at a matching concentration; dashed line histogram) antibody. Flow cytometric fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable cells.
Endoglin / CD105 Antibody (FITC), Rabbit MAb, Flow cytometric
[Click to enlarge image]
Caption:
Flow cytometric analysis of CD105 expression on human HUVEC cells. HUVEC cells (Human umbilical vein endothelial cells) were stained with FITC Rabbit anti-Human CD105 antibody (solid line fluorescence histogram) or a negative control at a matching concentration; dashed line histogram) antibody. Flow cytometric fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable cells.
Other CD105/ENG Antibody Products
Reactivity: Human  
Application: FCM  
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10149-MM11-F-25
10149-MM11-F-100
25 Test 
100 Tests 
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Reactivity: Human  
Application: 
    10149-MM05-50
    10149-MM05-200
    10149-MM05-100
    10149-MM05-1
    50 µg 
    200 µg 
    100 µg 
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    Reactivity: Human  
    Application: FCM  IF  ICC/IF  
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    10149-R103-50
    10149-R103-100
    50 µg 
    100 µg 
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    Reactivity: Human  
    Application: FCM  
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    10149-R103-C-25
    10149-R103-C-100
    25 Test 
    100 Tests 
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    Reactivity: Human  
    Application: ELISA  WB  
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    10149-RP02-50
    10149-RP02-200
    10149-RP02-100
    50 µg 
    200 µg 
    100 µg 
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    Reactivity: Human  
    Application: FCM  
    • Slide 1
    10149-MM13-50
    10149-MM13-200
    10149-MM13-100
    50 µg 
    200 µg 
    100 µg 
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    Reactivity: Human  
    Application: FCM  
    • Slide 1
    10149-R103-A-25
    10149-R103-A-100
    25 Test 
    100 Tests 
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    Reactivity: Human  
    Application: ELISA  
      10149-MM12-50
      10149-MM12-200
      10149-MM12-100
      50 µg 
      200 µg 
      100 µg 
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      Reactivity: Human  
      Application: ELISA  
        10149-MM11-50
        10149-MM11-200
        10149-MM11-100
        10149-MM11-1
        50 µg 
        200 µg 
        100 µg 
        1 mg 
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        Reactivity: Human  
        Application: FCM  
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        10149-MM13-C-25
        10149-MM13-C-100
        25 Test 
        100 Tests 
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        Reactivity: Human  
        Application: FCM  
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        10149-R103-F-25
        10149-R103-F-100
        25 Test 
        100 Tests 
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        Reactivity: Human  
        Application: ELISA  
          10149-R001-50
          10149-R001-100
          50 µg 
          100 µg 
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          Reactivity: Human  
          Application: FCM  
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          10149-R103-P-25
          10149-R103-P-100
          25 Test 
          100 Tests 
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          Reactivity: Human  
          Application: ELISA  
            10149-RP01-400
            10149-RP01-200
            10149-RP01-100
            400 µg 
            200 µg 
            100 µg 
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            Reactivity: Human  
            Application: FCM  
            • Slide 1
            10149-MM13-A-25
            10149-MM13-A-100
            25 Test 
            100 Tests 
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            Reactivity: Human  
            Application: IHC-P  
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            100088-RP02-50
            100088-RP02-200
            100088-RP02-100
            50 µg 
            200 µg 
            100 µg 
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            Reactivity: Human  
            Application: FCM  
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            10149-MM13-F-25
            10149-MM13-F-100
            25 Test 
            100 Tests 
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            Reactivity: Human  
            Application: FCM  
            • Slide 1
            10149-MM13-P-25
            10149-MM13-P-100
            25 Test 
            100 Tests 
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            Reactivity: Human  
            Application: WB  IF  ICC/IF  
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            100558-T34-50
            100558-T34-200
            100558-T34-100
            50 µg 
            200 µg 
            100 µg 
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            Reactivity: Mouse  
            Application: ELISA  IHC-P  
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            50407-RP02-50
            50407-RP02-100
            50 µg 
            100 µg 
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            Reactivity: Mouse  
            Application: FCM  
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            • Slide 1
            50407-R001-P-25
            50407-R001-P-100
            25 Test 
            100 Tests 
            Add to Cart
            Reactivity: Mouse  
            Application: 
              50407-R028-50
              50407-R028-100
              50407-R028-1
              50 µg 
              100 µg 
              1 mg 
              Add to Cart
              Reactivity: Mouse  
              Application: ELISA  WB  FCM  
              • Slide 1
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              50407-R001-50
              50407-R001-100
              50 µg 
              100 µg 
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              Reactivity: Mouse  
              Application: 
                50407-R029-50
                50407-R029-100
                50407-R029-1
                50 µg 
                100 µg 
                1 mg 
                Add to Cart
                Reactivity: Mouse  
                Application: ELISA  
                  50407-RP01-400
                  50407-RP01-200
                  50407-RP01-100
                  400 µg 
                  200 µg 
                  100 µg 
                  Add to Cart
                  Reactivity: Mouse  
                  Application: FCM  
                  • Slide 1
                  • Slide 1
                  50407-R001-F-25
                  50407-R001-F-100
                  25 Test 
                  100 Tests 
                  Add to Cart
                  Reactivity: Mouse  
                  Application: FCM  
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                  50407-R001-A-25
                  50407-R001-A-100
                  25 Test 
                  100 Tests 
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                  Endoglin/CD105  Background

                  Endoglin, also known as CD105, is a type I  homodimeric transmembrane glycoprotein with a large, disulfide-linked, extracellular region and a short, constitutively phosphorylated cytoplasmic tail. Endoglin contains an RGD tripeptide which is a key recognition structure in cellular adhesion,,suggesting a critical role for endoglin in the binding of endothelial cells to integrins and/or other RGD receptors. Endoglin is highly expressed on vascular endothelial cells, chondrocytes, and syncytiotrophoblasts of term placenta. It is also found on activated monocytes, mesenchymal stem cells and leukemic cells of lymphoid and myeloid lineages. As an accessory receptor for the TGF-β superfamily ligands, endoglin binds TGF-β1 and TGF-β3 with high affinity not by itself but by associating with TGF-β type I I receptor (TβRII) and activates the downstream signal pathways. In addition, in human umbilical vein endothelial cells, ALK-1 is also a receptor kinase for endoglin threonine phosphorylation, and mutations in either of the two genes result in the autosomal-dominant vascular dysplasia, hereditary hemorrhagic telangiectasia (HHT). Endoglin has been regarded as a powerful biomarker of neovascularization, and is associated with several solid tumor types.

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                  Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"