- EGFR Signaling Pathway
- TGF-beta Signaling
- Canonical Wnt Signaling
- non-Canonical Wnt Signaling
- Notch Signaling
- p53 Pathway
- NF-kB Pathway
- Cytokine Signaling
ERP72, also known as PDIA4, is an endoplasmic reticulum luminal protein which belongs to the protein disulfide isomerase family. ERP72 is a stress protein and participates in the catalysis of protein-S-S-bond rearrangement. Both of PDIA4 and PDIA3 function as proteases, protein disulfide isomerases, phospholipases or an arrangement of these. ERP72 compose part of a large chaperone multiprotein complex comprising CABP1, DNAJB11, HSP90B1, HSPA5, HYOU, PDIA2, PDIA4, PPIB, SDF2L1, UGT1A1 and very small amounts of ERP29, but not, or at very low levels, CALR nor CANX.
- Human ERP72/PDIA4 Protein, Recombinant, Cat NO: 13333-H08H
- Human ERP72/PDIA4 Protein, Recombinant, Cat NO: 13333-H02H
ERP72 ELISA Pair sets
ERP72 cDNA Clones
ERP70, ERP72, ERp-72, ER protein 70, ER protein 72, endoplasmic reticulum resident protein 70, endoplasmic reticulum resident protein 72, protein disulfide isomerase related protein (calcium-binding protein, intestinal-related), protein disulfide isomerase-associated 4, protein disulfide-isomerase A4 [Homo sapiens]
AI987846, Cai, ERp-72, Erp72, ER protein 72, calcium binding protein, intestinal, endoplasmic reticulum protein 72, endoplasmic reticulum resident protein 72, protein disulfide-isomerase A4 [Mus musculus]
Endoplasmic reticulum resident protein 72, Short name=ERp72
ERP72 was originally thought to be a deoxycytidine kinase.
ERP72 belongs to the protein disulfide isomerase family. ERP72 contains 3 thioredoxin domains.
ERP72 catalyzes the rearrangement of -S-S- bonds in proteins.
Part a large chaperone multiprotein complex comprising DNAJB11, HSP90B1, HSPA5, HYOU, PDIA2, PDIA4, PDIA6, PPIB, SDF2L1, UGT1A1 and very small amounts of ERP29, but not, or at very low levels, CALR nor CANX.
|Subcellular location:||Endoplasmic reticulum lumen. Melanosome. Note: Identified by mass spectrometry in melanosome fractions from stage I to stage IV.|
General information above from UniProt
- isomerase activity on S-S bonds in proteins
- ortholog to murine Cai